A Structural Perspective On Respiratory Complex I

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A Structural Perspective On Respiratory Complex I

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Author : Leonid Sazanov
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-05-11

A Structural Perspective On Respiratory Complex I written by Leonid Sazanov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-11 with Medical categories.

The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.

Cytochrome Oxidase

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Author : Mårten Wikström
language : en
Publisher:
Release Date : 1981

Cytochrome Oxidase written by Mårten Wikström and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Science categories.

Mitochondrial Oxidative Phosphorylation

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Author : Bernhard Kadenbach
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-23

Mitochondrial Oxidative Phosphorylation written by Bernhard Kadenbach and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-23 with Medical categories.

This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.

Neurodegenerative Diseases

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Author : Philip Beart
language : en
Publisher: Springer
Release Date : 2017-07-03

Neurodegenerative Diseases written by Philip Beart and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-03 with Medical categories.

Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years.

Molecular Biology Of The Cell

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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.

Anatomy And Physiology

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Author : J. Gordon Betts
language : en
Publisher:
Release Date : 2013-04-25

Anatomy And Physiology written by J. Gordon Betts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with categories.

Complexity

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Author : John Henry Holland
language : en
Publisher: Oxford University Press, USA
Release Date : 2014

Complexity written by John Henry Holland and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with History categories.

In this very short introduction, John Holland presents an introduction to the science of complexity. Using examples from biology and economics, he shows how complexity science models the behaviour of complex systems.

How Tobacco Smoke Causes Disease

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Author : United States. Public Health Service. Office of the Surgeon General
language : en
Publisher:
Release Date : 2010

How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Government publications categories.

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Interventional Pulmonology

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Author : Felix J.F. Herth
language : en
Publisher: European Respiratory Society
Release Date : 2017-12-01

Interventional Pulmonology written by Felix J.F. Herth and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Medical categories.

Lung Stem Cells In Development Health And Disease

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Author : Nikolic, Marko Z.
language : en
Publisher: European Respiratory Society
Release Date : 2021-04-01

Lung Stem Cells In Development Health And Disease written by Nikolic, Marko Z. and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Medical categories.

Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed for therapeutic purposes. The book focuses on stem cells in the mouse and human lung but also includes the ferret as an increasingly important new model organism. Chapters also discuss how lung tissue, including endogenous stem cells, can be generated in vitro from pluripotent stem cell lines. This state-of-the-art collection comprehensively covers one of the most exciting areas of respiratory science