Activity Dependent Long Term Potentiation Of Intrinsic Excitability In Hippocampal Ca1 Pyramidal Neurons
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Activity Dependent Long Term Potentiation Of Intrinsic Excitability In Hippocampal Ca1 Pyramidal Neurons
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Author : Jun Xu
language : en
Publisher:
Release Date : 2005
Activity Dependent Long Term Potentiation Of Intrinsic Excitability In Hippocampal Ca1 Pyramidal Neurons written by Jun Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Mechanisms Of Synaptic And Non Synaptic Plasticity In The Ca 1 Region Of The Hippocampus
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Author : Ann Emily Fink
language : en
Publisher:
Release Date : 2008
Mechanisms Of Synaptic And Non Synaptic Plasticity In The Ca 1 Region Of The Hippocampus written by Ann Emily Fink and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
The Hippocampus Book
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Author : Per Andersen
language : en
Publisher: Oxford University Press
Release Date : 2007
The Hippocampus Book written by Per Andersen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Magnesium In The Central Nervous System
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Author : Robert Vink
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Magnesium In The Central Nervous System written by Robert Vink and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Spike Timing Dependent Plasticity
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Author : Henry Markram
language : en
Publisher: Frontiers E-books
Release Date :
Spike Timing Dependent Plasticity written by Henry Markram and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Hebb's postulate provided a crucial framework to understand synaptic alterations underlying learning and memory. Hebb's theory proposed that neurons that fire together, also wire together, which provided the logical framework for the strengthening of synapses. Weakening of synapses was however addressed by "not being strengthened", and it was only later that the active decrease of synaptic strength was introduced through the discovery of long-term depression caused by low frequency stimulation of the presynaptic neuron. In 1994, it was found that the precise relative timing of pre and postynaptic spikes determined not only the magnitude, but also the direction of synaptic alterations when two neurons are active together. Neurons that fire together may therefore not necessarily wire together if the precise timing of the spikes involved are not tighly correlated. In the subsequent 15 years, Spike Timing Dependent Plasticity (STDP) has been found in multiple brain brain regions and in many different species. The size and shape of the time windows in which positive and negative changes can be made vary for different brain regions, but the core principle of spike timing dependent changes remain. A large number of theoretical studies have also been conducted during this period that explore the computational function of this driving principle and STDP algorithms have become the main learning algorithm when modeling neural networks. This Research Topic will bring together all the key experimental and theoretical research on STDP.
The Neuron Book
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Author : Nicholas T. Carnevale
language : en
Publisher: Cambridge University Press
Release Date : 2006-01-12
The Neuron Book written by Nicholas T. Carnevale and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-12 with Medical categories.
The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
Learning And Memory A Comprehensive Reference
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-07-07
Learning And Memory A Comprehensive Reference written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-07 with Medical categories.
Learning and Memory: A Comprehensive Reference, Second Edition is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition includes chapters that reflect the state-of-the-art of research in this area. Coverage of sleep and memory has been significantly expanded, while neuromodulators in memory processing, neurogenesis and epigenetics are also covered in greater detail. New chapters have been included to reflect the massive increase in research into working memory and the educational relevance of memory research. No other reference work covers so wide a territory and in so much depth. Provides the most comprehensive and authoritative resource available on the study of learning and memory and its mechanisms Incorporates the expertise of over 150 outstanding investigators in the field, providing a ‘one-stop’ resource of reputable information from world-leading scholars with easy cross-referencing of related articles to promote understanding and further research Includes further reading for each chapter that helps readers continue their research Includes a glossary of key terms that is helpful for users who are unfamiliar with neuroscience terminology
Concise Learning And Memory
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-05-25
Concise Learning And Memory written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-25 with Psychology categories.
The study of learning and memory is a central topic in neuroscience and psychology. Many of the basic research findings are directly applicable in the treatment of diseases and aging phenomena, and have found their way into educational theory and praxis. Concise Learning and Memory represents the best 30 chapters from Learning and Memory: A comprehensive reference (Academic Press March 2008), the most comprehensive source of information about learning and memory ever assembled, selected by one of the most respective scientists in the field, John H. Byrne. This concise version provides a truly authoritative collection of overview articles representing fundamental reviews of our knowledge of this central cognitive function of animal brains. It will be an affordable and accessible reference for scientists and students in all areas of neuroscience and psychology. There is no other single-volume reference with such authority and comprehensive coverage and depth currently available. * Represents an authoritative selection of the fundamental chapters from the most comprehensive source of information about learning and memory ever assembled, Learning and Memory - A comprehensive reference (Academic Press Mar 2008) * Representing outstanding scholarship, each chapter is written by a leader in the field and an expert in the topic area * All topics represent the most up to date research * Full color throughout, heavily illustrated * Priced to provide an affordable reference to individuals and workgroups
Structure To Function Of G Protein Gated Inwardly Rectifying Girk Channels
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-09-23
Structure To Function Of G Protein Gated Inwardly Rectifying Girk Channels written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-23 with Science categories.
This volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into GIRK Potassium Channels. It reviews current knowledge and understanding and provides a starting point for researchers and practitioners entering the field. Presents a comprehensive overview of the latest research into GIRK potassium channels Serves as a perfect starting point for researchers and practitioners entering the field Expands the literature and field of neurobiology
Memory Mechanisms In Health And Disease Mechanistic Basis Of Memory
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Author : Karl Peter Giese
language : en
Publisher: World Scientific
Release Date : 2012-06-07
Memory Mechanisms In Health And Disease Mechanistic Basis Of Memory written by Karl Peter Giese and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Medical categories.
Memory Mechanisms is an edited review volume that summarizes state-of-the-art knowledge on memory mechanisms at the molecular, cellular and circuit level. Each review is written by leading experts in the field, presenting not only current knowledge, but also discussing the concepts, providing critical reflections and suggesting an outlook for future studies. The memory mechanisms are also discussed in the context of diseases. Studies of memory deficits in disease models are introduced as well as approaches to restore memory deficits. Finally, the impact of contemporary memory research for psychiatry is illustrated.