Adrenomedullin In Cardiovascular Disease
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Adrenomedullin In Cardiovascular Disease
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Author : Toshio Nishikimi
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-04-28
Adrenomedullin In Cardiovascular Disease written by Toshio Nishikimi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-28 with Medical categories.
Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has a role in the pathogenesis of arteriosclerosis. Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease. Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.
The Role Of Nitric Oxide And Adrenomedullin In Cardiovascular Failure In Septic Shock
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Author : Qixian Shan
language : en
Publisher:
Release Date : 2017-01-27
The Role Of Nitric Oxide And Adrenomedullin In Cardiovascular Failure In Septic Shock written by Qixian Shan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with categories.
This dissertation, "The Role of Nitric Oxide and Adrenomedullin in Cardiovascular Failure in Septic Shock" by Qixian, Shan, 單綺嫻, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b3124226 Subjects: Nitric oxide - Physiological aspects Adrenomedullin - Physiological aspects Septic shock Heart failure
Endocrinology Of Cardiovascular Function
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Author : Ellis R. Levin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Endocrinology Of Cardiovascular Function written by Ellis R. Levin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Endocrinology of Cardiovascular Function is a fitting inauguration to the Endocrine Update Series. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Historically, our understanding of hormonal disturbances was restricted to the classical secretory glands and their targets. As Endocrinology of Cardiovascular Function so aptly indicates, endocrinology is no longer constrained by our early physiologic understanding of glandular disorder. Endocrinology of Cardiovascular Function has set the standard of excellence for the future volumes in this series. Shlomo Melmed, M.D. Series Editor, Endocrine Update Growth factors such as IGF-1 play important roles in cardiovascular cell hypertrophy and the response to acute vascular injury. From another perspective, traditional endocrine hormones, such as estrogen, have been found to participate in preventing the development of atherosclerosis in women, acting through novel mechanisms on target vascular cells. Other `endocrine' hormones, such as PTHRP and adrenomedullin, also modulate cardiovascular and renovascular dynamic states, suggesting new roles for these peptides as vasodilators. This multi-authored text is dedicated to highlighting emerging and important new information regarding the endocrinology of the cardiovascular system. Ellis R. Levin, M.D.
Adrenomedullin In Cardiovascular Disease
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Author : Toshio Nishikimi
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-07-25
Adrenomedullin In Cardiovascular Disease written by Toshio Nishikimi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-25 with Medical categories.
Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.
The Role Of Nitric Oxide And Adrenomedullin In Cardiovascular Failure In Septic Shock
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Author : Qixian Shan
language : en
Publisher:
Release Date : 2001
The Role Of Nitric Oxide And Adrenomedullin In Cardiovascular Failure In Septic Shock written by Qixian Shan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Adrenomedullin categories.
Physiological And Molecular Mechanisms For Cardiovascular Effects Of Central Adrenomedullin
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Author : Yong Xu
language : en
Publisher:
Release Date : 2007
Physiological And Molecular Mechanisms For Cardiovascular Effects Of Central Adrenomedullin written by Yong Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Adrenomedullin categories.
Cardiac Biomarkers
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Author : Alan S. Maisel
language : en
Publisher: Springer
Release Date : 2016-10-24
Cardiac Biomarkers written by Alan S. Maisel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-24 with Medical categories.
This book covers ACS and Heart Failure, the chapters represent the most current, up to date and knowledgeable content on the topic available. It is written by the worlds most respected leaders in biomarkers, with a majority emphasis on what clinicians need to know. The Editors and their contributors have provided algorithms, annotated case discussions and caveats. They cover biomarkers to predict risk of heart disease, biomarkers of cardiorenal disease , and conclude with a section on new and emerging biomarkers. It be genuinely helpful and practical to those in the field, including not just people working in the field, but nurses, doctors, etc who practice medicine in the clinic, the emergency department and the hospital.
Cardiac Biomarkers Expert Advice For Clinicians
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Author : Alan S Maisel
language : en
Publisher: JAYPEE BROTHERS PUBLISHERS
Release Date : 2012-03-13
Cardiac Biomarkers Expert Advice For Clinicians written by Alan S Maisel and has been published by JAYPEE BROTHERS PUBLISHERS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-13 with Medical categories.
The purpose of the book is nicely worded in the introduction: 'make good doctors better'. Motivate the clinicians to use biomarkers to obtain up-to-date background knowledge regarding tools they use every day clinically, such as cardiac troponin and natriuretic peptides. Biomarkers have become essential clinical tools in the early diagnosis of acute myocardial infarction and the early diagnosis of heart failure, as well as potentially helpful tools in many other indications. Beyond doubt, Cardiac Biomarkers-Expert Advice for Clinicians will achieve its purpose. Cardiac Biomarkers-Expert Advice.
Precursor Peptides Of Adrenomedullin Endothelin And Vasopressin In The Diagnosis Of Heart Failure
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Author : Lorenz Matthias Buser
language : en
Publisher:
Release Date : 2010
Precursor Peptides Of Adrenomedullin Endothelin And Vasopressin In The Diagnosis Of Heart Failure written by Lorenz Matthias Buser and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
New Factors That Affect Adrenomedullin Expression
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Author : Hoi-Kin Wong
language : en
Publisher:
Release Date : 2017-01-26
New Factors That Affect Adrenomedullin Expression written by Hoi-Kin Wong and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-26 with categories.
This dissertation, "New Factors That Affect Adrenomedullin Expression" by Hoi-kin, Wong, 黃凱健, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: ADM is a 52-amino acid peptide which carries out multiple biological functions in cardiovascular system such as vasodilation and hypotension, and is a prognostic marker for cardiovascular diseases. Recent studies show that its plasma level is elevated in diabetes, however the reason and significance for such an increase has not been understood. Recent research has proposed that inflammation and oxidative stress both contribute to the pathogenesis of diabetes. If ADM is a marker in diabetes, it is possible that ADM is regulated by these two mechanisms, and so this project aims to investigate how these mechanisms could affect ADM expression. Recent studies have demonstrated that advanced glycation endproducts (AGEs) could lead to development of various diabetic complications. AGEs are formed as intermediate product in the non-enzymatic glycation of reducing sugars. Formation of these products is stimulated by hyperglycemia and oxidative stress, which could also induce ADM expression. Hence one of the studies investigated the direct effect of AGEs on ADM expression in an in vitro model. A rat macrophage cell line NR8383 was used to investigate the dose-response and time-point responses of macrophage cells in expressing ADM stimulated by AGEs. 6 hours of AGEs treatment resulted in no significant effect on ADM gene expression. The gene expression increased in all time points in which the change was at maximum after 1 hour of AGE treatment compared with other time points (PADM plays a role in inflammation that it could influence IL-6 and adiponectin expressions. This project also investigated whether IL-6 and adiponectin could affect ADM levels on the opposite. The associations between IL6 and adiponectin single nucleotide polymorphisms (SNPs) with plasma ADM levels were studied using a cohort of 476 subjects from the Cardiovascular Risk Factor Prevalence Study (CRISPS). Specific tagging SNPs were genotyped for the 476 subjects. Significant associations were identified for the IL6 SNP rs17147230 and adiponectin SNP rs182052 with plasma ADM levels in additive model (β=-0.096, P=0.034, and β=0.104, P=0.023 respectively adjusting for age and sex). The associations remained significant after adjusting for various covariates (PDOI: 10.5353/th_b5153742 Subjects: Oxidative stress Adrenomedullin Inflammation