Advanced Techniques In Diagnostic Cellular Pathology

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Advanced Techniques In Diagnostic Cellular Pathology

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Author : Mary Hannon-Fletcher
language : en
Publisher: John Wiley & Sons
Release Date : 2009-03-12

Advanced Techniques In Diagnostic Cellular Pathology written by Mary Hannon-Fletcher and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-12 with Science categories.

In recent years cellular pathology has become more closely involved in the direct management of patients with the introduction of molecular technologies and targeted therapies. Advanced Techniques in Diagnostic Cellular Pathology introduces students and professionals to these concepts and the key technologies that are influencing clinical practice today. Each chapter is carefully structured to introduce the very latest techniques and describe their clinical purpose, principle, method and application in cellular pathology. The advantages of various methods for preparing, observing and demonstrating cells and tissues employed to assist in diagnosis are explored, in addition to the use of quantitative methods in the detection and diagnosis of disease. Supplementary web-based material including annotated virtual microscope slides is available with the book. This is provided courtesy of i-Path Diagnostics Ltd and can be accessed online from their website www.pathxl.com Describes the very latest, emerging and established molecular aspects of diagnostic pathology. A clear, focused approach with each chapter containing a summary, a review of basic principles and clinical applications. Includes web-based annotated virtual microscope slides. Contributions from experienced practitioners contain numerous real-world examples illustrating the use of different diagnostic techniques, and their clinical relevance Written by a team of experienced practitioners this book will prove invaluable both to postgraduate biomedical science students who are training to be cellular pathologists and to professionals working in diagnostic and research laboratories as part of their continuing professional development.

Toxicologic Pathology

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Author : Pritam S. Sahota
language : en
Publisher: CRC Press
Release Date : 2018-08-14

Toxicologic Pathology written by Pritam S. Sahota and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-14 with Medical categories.

Following the success of the first edition, this book is designed to provide practical and timely information for toxicologic pathologists working in pharmaceutical drug discovery and development. The majority of the book (Organ Systems) will provide detailed descriptions of histopathological lesions observed in drug development. In addition, it will provide information to assist the pathologist in making determinations of the origin of lesions as well as its relevance to human risk. Toxicologic Pathology: Nonclinical Safety Assessment, Second Edition includes 2 new concept chapters. The first of the new chapters address approaches for the evaluation of unique therapeutic modalities such as cell therapies, gene therapies, and gene expression knockdown therapies. While these still represent new developing therapeutic approaches, there has been significant experience with the therapeutic modalities in the last 5 years. The second new chapter addresses the nonclinical safety assessment of medical devices, a topic of increasing importance that was not addressed in a unique chapter in the first edition. The other concept chapters have been updated and cover important topics including the overview of drug development; principles of nonclinical safety assessment; an introduction to toxicologic pathology; techniques used in toxicologic pathology, clinical pathology, toxicokinetics, and drug development toxicogenomics; and spontaneous lesions. The 13 organ system chapters provide the specifics related to pathologic characteristics, differential diagnosis, and interpretation of toxic responses in each organ system. These chapters are specifically important for the bench pathologist but also for the toxicologist who interacts with pathologists and function as study toxicologists and project team representatives in the drug development arena.

Handbook Of Research On Advanced Techniques In Diagnostic Imaging And Biomedical Applications

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Author : Exarchos, Themis P.
language : en
Publisher: IGI Global
Release Date : 2009-04-30

Handbook Of Research On Advanced Techniques In Diagnostic Imaging And Biomedical Applications written by Exarchos, Themis P. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-30 with Computers categories.

"This book includes state-of-the-art methodologies that introduce biomedical imaging in decision support systems and their applications in clinical practice"--Provided by publisher.

Diagnostic Molecular Pathology

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Author : William B. Coleman
language : en
Publisher: Academic Press
Release Date : 2023-10-18

Diagnostic Molecular Pathology written by William B. Coleman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-18 with Science categories.

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease

Advanced Techniques In Diagnostic Microbiology

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Author : Yi-Wei Tang
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-14

Advanced Techniques In Diagnostic Microbiology written by Yi-Wei Tang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-14 with Medical categories.

In the United States, hospitals annually report over 5 million cases of infectious-disease-related illnesses: clinical microbiology laboratories in these hospitals are engaged in detecting and identifying the pathogenic microorganisms in clinical specimens collected from these patients with suspected infections. Clearly, the timely and accurate detection/identification of these microbial pathogens is critical for patient treatment decisions and outcomes for millions of patients each year. Despite an appreciation that the outcome of an infectious-disease-related illness is directly related to the time required to detect and identify a microbial pathogen, clinical microbiology laboratories in the United States as well as worldwide have long been hampered by traditional culture-based assays, which may require prolonged incubation time for slowly growing microorganisms such as Mycobacterium tuberculosis. Moreover, traditional culture-based assays often require multiple steps with additional time needed for discernment of species and/or detection of antimicrobial resistance. Finally, these traditional, slow multistep culture-based assays are labor-intensive and required skilled clinical microbiologists at the bench. Over the past several decades, advanced molecular techniques in diagnostic microbiology quietly have been revolutionizing the practice of clinical microbiology in the hospital setting. Indeed, molecular diagnostic testing in general and nucleic-acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. There is no question that the development of rapid molecular techniques for nucleic acid amplification/characterization combined with automation and user-friendly software has greatly broadened the diagnostic capabilities of the clinical microbiology laboratory. These technical advances in molecular microbiology over the first decade of the 21st Century have profoundly influenced the physical structure of clinical microbiology laboratories as well as their staffing patterns, workflow, and turnaround time. These molecular microbiology advances have also resulted in the need for a revised and updated second edition of Advanced Techniques in Diagnostic Microbiology. This second edition again provides an updated and comprehensive description of the ongoing evolution of molecular methods for the diagnosis of infectious diseases. In addition, many new chapters have been added, including a chapter on the clinical interpretation and relevance of advanced technique results. The second edition, like the first edition, includes both a “techniques” section describing the latest molecular techniques and an “applications” section describing how these advanced molecular techniques are being used in the clinical setting. Finally, the second edition, like the first edition, utilizes a diverse team of authors who have compiled chapters that provide the reader with comprehensive and useable information on advanced molecular microbiology techniques.

Cellular Pathology

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Author : D. J. Cook
language : en
Publisher: Scion Pub Limited
Release Date : 2006-01

Cellular Pathology written by D. J. Cook and has been published by Scion Pub Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01 with Medical categories.

"a concise textbook of histological techniques for students studying courses in biomedical sciences or other subjects or other subjects allied to medicine. The book describes the complete range of techniques utilised in the diagnos od disease and in pathology research." -- Back cover.

Basic And Advanced Laboratory Techniques In Histopathology And Cytology

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Author : Pranab Dey
language : en
Publisher: Springer
Release Date : 2018-06-08

Basic And Advanced Laboratory Techniques In Histopathology And Cytology written by Pranab Dey and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-08 with Medical categories.

This book provides detailed information on basic and advanced laboratory techniques in histopathology and cytology. It discusses the principles of and offers clear guidance on all routine and special laboratory techniques. In addition, it covers various advanced laboratory techniques, such as immunocytochemistry, flow cytometry, liquid based cytology, polymerase chain reaction, tissue microarray, and molecular technology. Further, the book includes numerous color illustrations, tables and boxes to familiarize the reader with the work of a pathology laboratory. The book is mainly intended for postgraduate students and fellows in pathology as well as practicing pathologists. The book is also relevant for all the laboratory technicians and students of laboratory technology.

Histopathology Techniques And Its Management

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Author : Ramadas Nayak
language : en
Publisher: JP Medical Ltd
Release Date : 2017-12-31

Histopathology Techniques And Its Management written by Ramadas Nayak and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-31 with Medical categories.

This book is a complete guide to histopathology techniques for trainees. Beginning with an introduction to tissue examination, the next chapters discuss fixation and fixatives, tissue processing and embedding, decalcification, microtomy and section cutting, and frozen section and cryostat. The following sections cover different staining procedures, immunohistochemistry, and automation in histopathology, concluding with chapters on biological waste management and quality management. Each chapter includes a self-assessment exercise with short notes and answers, and the comprehensive text is further enhanced by nearly 350 clinical photographs, diagrams and tables. Key points Complete guide to histopathology techniques for trainees Provides detail on different staining procedures, immunohistochemistry, and automation Features self-assessment exercises with notes and answers Highly illustrated with clinical photographs, diagrams and tables

Advanced Diagnostic Methods In Pathology

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Author : Timothy J. O'Leary
language : en
Publisher: Saunders
Release Date : 2003

Advanced Diagnostic Methods In Pathology written by Timothy J. O'Leary and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.

Providing a comprehensive overview of all the diagnostic techniques used in modern pathology laboratories, this textbook considers both diagnostic and prognostic applications of immunopathologic, molecular biologic, flow cytometric, and image analysis methods. The basic science behind each diagnostic method is outlined, and entire chapters focus on specific diagnostic issues for each organ system. O'Leary is affiliated with the Armed Forces Institute of Pathology. Annotation copyrighted by Book News, Inc., Portland, OR

Toxicologic Pathology

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Author : Page R. Bouchard
language : en
Publisher: CRC Press
Release Date : 2025-06-23

Toxicologic Pathology written by Page R. Bouchard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-23 with Medical categories.

The new edition provides practical and timely information for toxicologic pathologists working in drug discovery and development. The introductory concept chapters are consolidated into two more concise and better-organized introductory chapters. The two concept chapters introduce the reader to pharmaceutical R&D, the role of the pathologist in the process, and critical partner scientific disciplines with whom the pathologist will collaborate. In this revision, the organ system chapters incorporate more consistent commentary and guidance on the molecular mechanism of action, human translational relevance, and regulatory impact of pathological findings as they are described in these chapters. Key Features: Aids scientists in understanding spontaneously occurring and compound-related pathological findings Features three new well-respected scientists on the editorial team Includes more consistent commentary and guidance in the organ system chapters