Advancement And New Understanding In Brain Injury


Advancement And New Understanding In Brain Injury
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Advancement And New Understanding In Brain Injury


Advancement And New Understanding In Brain Injury
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Author : Zamzuri Idris
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-07-07

Advancement And New Understanding In Brain Injury written by Zamzuri Idris and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-07 with Medical categories.


This book covers the latest developments in the understanding and treatment of traumatic brain injury. Various world experts authored the chapters that comprise a wealth of updated information on intracranial pressure; monitoring and diagnostic methods; neuroinflammatory responses in traumatic brain injury; cerebral palsy and Covid-19–related brain disorder; pathogenesis and prevention of fetal, neonatal, infant, and child brain injury; hyperbaric oxygenation treatment; the engineering and modeling of head injury; systematic review on early-tracheostomy; intracranial aneurysm in tuberous sclerosis complex; and the neurobehavioral and cognitive aspects of brain injury. With these complex topics, every clinician, scientist, and researcher will find this book invaluable in understanding the latest improvements and advances in the diagnosis and treatment of traumatic brain injury.



Current Progress In The Understanding Of Secondary Brain Damage From Trauma And Ischemia


Current Progress In The Understanding Of Secondary Brain Damage From Trauma And Ischemia
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Author : A. Baethmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Current Progress In The Understanding Of Secondary Brain Damage From Trauma And Ischemia written by A. Baethmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation – mother nature’s experiment – or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components – LDL/fibrinogen – by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis.



Understanding Traumatic Brain Injury


Understanding Traumatic Brain Injury
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Author : Harvey Levin
language : en
Publisher: Oxford University Press
Release Date : 2014-01-28

Understanding Traumatic Brain Injury written by Harvey Levin and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-28 with Psychology categories.


This timely book reports recent progress in research on traumatic brain injury (TBI) by leading investigators encompassing translational and clinical studies. The text covers epidemiology, pathophysiology, brain imaging, cognition, behavioral sequelae, and clinical trials of innovative treatments, including new approaches to rehabilitation. The range of TBI mechanisms represented in this cutting-edge book includes closed head trauma and blast-related injury, and the spectrum of TBI severity. Chapters offer a developmental perspective, including the effects of TBI on cognitive development in children and outcome studies in adults. Contributors from various countries provide a global perspective on this worldwide health problem. The editors have synthesized the contents in a concluding chapter. Researchers and clinicians will find this volume to be an informative, authoritative reference for current TBI research.



Fetal And Neonatal Brain Injury


Fetal And Neonatal Brain Injury
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Author : David K. Stevenson
language : en
Publisher: Cambridge University Press
Release Date : 2017-12-21

Fetal And Neonatal Brain Injury written by David K. Stevenson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-21 with Medical categories.


Authoritative, practical clinical text giving clear management advice on diagnosis, treatment and outcomes of all fetal and neonatal brain injuries.



Cerebral Blood Flow Metabolism And Head Trauma


Cerebral Blood Flow Metabolism And Head Trauma
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Author : Christian W. Kreipke
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-07

Cerebral Blood Flow Metabolism And Head Trauma written by Christian W. Kreipke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-07 with Medical categories.


Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.



Translational Research In Traumatic Brain Injury


Translational Research In Traumatic Brain Injury
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Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2015-12-01

Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-01 with Medical categories.


Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.



Fetal And Neonatal Brain Injury


Fetal And Neonatal Brain Injury
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Author : David Kendal Stevenson
language : en
Publisher: Oxford University Press, USA
Release Date : 1997

Fetal And Neonatal Brain Injury written by David Kendal Stevenson and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Family & Relationships categories.


This book evaluates the numerous events in pregnancy, labor, and post-partum care that can lead to brain damage in newborn infants. The mechanisms by which the brain is damaged, as well as the approaches to treatment and most importantly, prevention of injury are detailed. Sixteen new chapters have been added to the Second Edition, and all the others have been fully updated. New chapters cover subjects such as ischemic cell injury, reperfusion injury, experimental models of perinatal brain injury, hypoxemic-ischemic encephalopathy, congenital malformations of the brain, perinatal infections, and metabolic disorders in the developing CNS. A chapter devoted exclusively to hemorrhagic lesions of the brain has been added as well. The new edition incorporates the most recent advances in neurology, neurosurgery, and neuroimaging, including the rapidly improving imaging techniques for identifying the extent of brain injury, the better ante- and post-partum management of infants, and the development of better understanding of the cellular mechanism of injuries to the brain.



Neural Plasticity And Cognitive Development


Neural Plasticity And Cognitive Development
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Author : Joan Stiles
language : en
Publisher: Oxford University Press
Release Date : 2012-05-24

Neural Plasticity And Cognitive Development written by Joan Stiles and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-24 with Medical categories.


The advent of modern neurobiological methods over the last three decades has provided overwhelming evidence that it is the interaction of genetic factors and the experience of the individual that guides and supports brain development. Brains do not develop normally in the absence of critical genetic signaling, and they do not develop normally in the absence of essential environmental input. The key to understanding the origins and emergence of both the brain and behavior lies in understanding how inherited and environmental factors are engaged in the dynamic and interactive processes that define and direct development of the neurobehavioral system. Neural Plasticity and Cognitive Development focuses on children who suffered focal brain insult (typically stroke) in the pre- or perinatal period which provides a model for exploring the dynamic nature of early brain and cognitive development. In most, though not all, of the cases considered, the injuries affect substantial portions of one cerebral hemisphere, resulting in patterns of neural damage that would compromise cognitive ability in adults. However, longitudinal behavioral studies of this population of children have revealed only mild cognitive deficits, and preliminary data from functional brain imaging studies suggest that alternative patterns of functional organization emerge in the wake of early injury. Neural Plasticity and Cognitive Development posits that the capacity for adaptation is not the result of early insult. Rather, it reflects normal developmental processes which are both dynamic and adaptive operating against a backdrop of serious perturbation of the neural substrate.



Brain Neurotrauma


Brain Neurotrauma
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Author : Firas H. Kobeissy
language : en
Publisher: CRC Press
Release Date : 2015-02-25

Brain Neurotrauma written by Firas H. Kobeissy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Science categories.


Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.



Recovery After Traumatic Brain Injury


Recovery After Traumatic Brain Injury
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Author : Barbara P. Uzzell
language : en
Publisher: Psychology Press
Release Date : 2014-02-04

Recovery After Traumatic Brain Injury written by Barbara P. Uzzell and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-04 with Psychology categories.


Emotions, behaviors, thoughts, creations, planning, daily physical activities, and routines are programmed within our brains. To acquire these capacities, the brain takes time to fully develop--a process that may take the first 20 years of life. Disruptions of the brain involving neurons, axons, dendrites, synapses, neurotransmitters or brain infrastructure produce profound changes in development and functions of the one organ that makes us unique. To understand the functions and development of the brain is difficult enough, but to reverse the consequences of trauma and repair the damage is even more challenging. To meet this challenge and increase understanding, a host of disciplines working and communicating together are required. The International Association for the Study of Traumatic Brain Injury tried to correct this limitation during its meetings of international clinicians, researchers, and scientists from many fields. It was felt that many of the outstanding thoughts and ideas from the participants' most recent meeting and from others working in the field of traumatic brain injury (TBI) should be shared. This book was conceived not as proceedings of the conference, but as a collection of knowledge for those working in the acute and chronic recovery aspects of head injury. This book reflects the importance of the team approach to patients with TBI. The chapter authors come from a diverse array of disciplines--basic science, neurosurgery, neurology, radiology, psychology, neuropsychology, and legal, consumer, and speech/language science. Their contributions provide the most current research and the latest ways of managing a variety of aspects of TBI.