Advances In Bone Marrow Purging And Processing
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Advances In Bone Marrow Purging And Processing
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Author : Adrian P. Gee
language : en
Publisher: Wiley-Liss
Release Date : 1994-10-04
Advances In Bone Marrow Purging And Processing written by Adrian P. Gee and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-04 with Medical categories.
Examines emerging technology in this field, from both the research and clinical arenas. The book describes approaches for utilizing DNA sense and antisense probes, combinations of elutriators and immunomagnetics as well as refinements in the use of mechanical separation. Contributions from more than 400 investigators address topics such as pharmacological purging, marrow processing, clinical studies and tumor cell detection.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1990
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medicine categories.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
First multi-year cumulation covers six years: 1965-70.
Advances In Bone Marrow Purging And Processing
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Author : Diana A. Worthington-White
language : en
Publisher:
Release Date : 1992
Advances In Bone Marrow Purging And Processing written by Diana A. Worthington-White and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.
Red Cell Transfusion
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Author : Marion E. Reid
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Red Cell Transfusion written by Marion E. Reid and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Authoritative experts in transfusion medicine describe in critical detail the most important procedures for obtaining, selecting, and transfusing red blood cells to patients. The topics covered include such key issues as transfusion problems in the immunocompromised, the complications of autoantibodies, transfusion of infants with hemolytic disease, difficulties arising from solid organ transplantation, stem cell transfusions, and the challenges of massive transfusion. Also discussed are the use, limitations, and alternatives to autogeneic cells; long-term red cell transfusion; the management of adverse reactions to red cell transfusions; and the question of blood group antigens and their association with disease and differential diagnosis. The book offers transfusion specialists fresh insights and information to maximize and extend their current knowledge.
Cell Separation Methods And Applications
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Author : Diether Recktenwald
language : en
Publisher: CRC Press
Release Date : 1997-11-04
Cell Separation Methods And Applications written by Diether Recktenwald and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-11-04 with Medical categories.
"Offers complete coverage and assessment of cell separation technologies for analytical and preparative isolations of biological cell populations-demonstrating how to select and devise optimal sorting strategies for applications in biochemistry, immunology, cell and molecular biology, and clinical research. "
Blood Stem Cell Transplantation
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Author : Jane N. Winter
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Blood Stem Cell Transplantation written by Jane N. Winter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. Some of the applications that stand to impact this field most significantly are based on recent advances in the biological sciences, as demonstrated by the chapters on gene therapy, on the detection of minimal residual disease using molecular techniques, and on the use of radioimmunoconjugates targeting lymphoma and leukemia-associated antigens. Others are the results of clinical observations - e.g., the association between graft-versus-host- disease (GVHD) and durable remissions that have led to creative clinical experiments such as donor leukocyte infusions (DLI). Attempts to unravel the biological events that underlie the responses seen in patients with relapsed chronic myelogenous leukemia treated with DLI are likely to provide the basis for future refinements in this clinical approach. Hopefully, improved response rates and reduced toxicity will result. The power of the immunologic response in controlling malignant disease is underscored in the chapter on post-transplant immunotherapy. The complex immunologic process that results in clinical GVHD may be dissected and engineered to provide clinical benefits that include, in addition to its antineoplastic effects, the amelioration of its clinical manifestations. Better control of GVHD with less global immunosuppression will facilitate the use of mismatched and unrelated donors. This area of investigation perfectly illustrates the continued interplay between the laboratory and the clinic. The continued cross-fertilization of ideas between immunologists, molecular biologists and clinical investigators is likely to yield important advances in this field for years to come. Possible applications of stem cell transplantation continue to grow with the identification of alternative sources of stem cells and the potential to engineer and/orexpand the graft. Although the use of unrelated and mismatched donors continues to increase, the possibilities associated with umbilical cord blood transplantation are legion, especially if stem cells can be expanded ex vivo to provide grafts for full-sized adults. Using techniques in which contaminating malignant cells may be eliminated from autografts through positive selection, autologous transplantation may prove highly effective, especially when coupled with post-transplant immunotherapy. Some of these same methodologies have helped facilitate the use of autologous grafts for transplantation in patients with chronic myelogenous leukemia without allogeneic donors. Advances in the supportive care of transplant patients, including the pretransplant identification of those at risk from pulmonary complications and the use of cytokines to speed engraftment, have reduced morbidity and mortality to such a degree that it is appropriate to consider high-dose therapy and stem cell reconstitution in patients with nonmalignant diseases. The impressive advances that have occurred in transplantation for thalassemia are described by pioneers in their area of investigation. The burgeoning field of transplantation for autoimmune disorders, including its immunobiologic basis and soon-to- be-realized clinical potential, is also summarized. Continued progress in the use of high-dose therapy with stem cell rescue for the treatment of pediatric tumors, which derives in part from improved supportive care, is detailed. The sobering voice of the health care economists underscores the necessary limitations to our seemingly unbridled imagination. Cost- consciousness and financial know-how will need to be reflected in future study designs. Given the seemingly endless applications of our technology, strategies to insure its cost-effectiveness will be necessary. Continued financial support for laboratory investigation and for the clinical experiments they generate will be required if we are to go forward. Blood Stem Cell Transplantation lays the foundation for many of these future advances; it is incumbent upon us all to insure its realization.
Autologous Stem Cell Transplantation
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Author : Angelo Carella
language : en
Publisher: Routledge
Release Date : 2020-08-26
Autologous Stem Cell Transplantation written by Angelo Carella and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Medical categories.
This textbook integrates basic research and clinical aspects underlying the most recent results in those malignant diseases where progress is most effective. Recent evidence shows that higher doses are better in inducing higher cure rates in hematological neoplasias, although myeloblation related to dose intensity can be a limiting factor. The toxicity can now be controlled with autologous marrow and peripheral blood progenitor cell transplantation, used with or without growth factors. The combination of high dose chemoradiotherapy followed by re-infusion of autologous stem cells constitute a dramatic advance in the treatment of refactory and relapse hematological neoplasias.
Advances In Bone Marrow Purging And Processing
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Author : Diana A. Worthington-White
language : en
Publisher: Wiley
Release Date : 1992-09-11
Advances In Bone Marrow Purging And Processing written by Diana A. Worthington-White and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-09-11 with Medical categories.
Surveys the latest research discoveries and current clinical procedures for selectively separating and analyzing subpopulations of cells from bone marrow. Over 400 internationally renowned experts offer contributions on such topics as approaches for using DNA sense and antisense probes, combinations of elutriators and immunomagnetics, expanded cytokines applications, new techniques for the removal of tumor cells from autologous bone marrow and T cells from allogeneic grafts.
Annual Report
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Author : National Cancer Institute (U.S.). Division of Cancer Biology, Diagnosis, and Centers
language : en
Publisher:
Release Date : 1995
Annual Report written by National Cancer Institute (U.S.). Division of Cancer Biology, Diagnosis, and Centers and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.