Advances In Genomic And Genetic Tools And Their Applications For Understanding Embryonic Development And Human Diseases
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Advances In Genomic And Genetic Tools And Their Applications For Understanding Embryonic Development And Human Diseases
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Author : Muhammad Abu-Elmagd
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-02
Advances In Genomic And Genetic Tools And Their Applications For Understanding Embryonic Development And Human Diseases written by Muhammad Abu-Elmagd and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-02 with Science categories.
Unraveling Genetic Mysteries Longevity Genetic Engineering And Philosophy Of Mind
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
Unraveling Genetic Mysteries Longevity Genetic Engineering And Philosophy Of Mind written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Health & Fitness categories.
Genetics is a fascinating and complex field, which reveals the secrets of the genetic code present in every living being. Through the investigation of genes and their interaction with the environment, we are able to better understand the biological processes that shape our existence. In this book, we'll explore the wonders and challenges of genetics, as well as its applications in areas such as medicine, criminal investigation, and genetic engineering. The first part of this book will take us through the intricate world of the genetics of aging and longevity. We will investigate the genetic mechanisms that determine the rate of aging of organisms and explore the possibilities of prolonging a healthy life. We'll discover how the latest research is unlocking the mysteries of aging and offering new insights into human longevity. Then we will enter the field of genetic engineering and genetically modified organisms (GMOs). We will explore the innovative techniques that allow the manipulation of DNA and the creation of organisms with specific characteristics. We'll see how this technology is revolutionizing agriculture, medicine, and industry, while raising important ethical and environmental questions. Forensic genetics will also gain prominence on our journey. We will investigate how DNA analysis has become a powerful tool in solving crimes, unraveling mysteries and assisting in the pursuit of justice. We'll discover how technological advances are revolutionizing criminal investigation and providing a deeper understanding of the genetic bonds between individuals. Entering the field of health, we will explore the genetics of neurodegenerative, cardiovascular, autoimmune and psychiatric disorders. We will understand how genes play a key role in the development of these diseases and how this understanding can open the way to more effective treatments and prevention strategies. In addition, we will investigate pharmacogenomics and precision medicine, examining how genetic individuality influences individuals' response to medications, enabling personalized and more effective treatments. We'll also cover the genetics of metabolism and obesity, sleep disorders, and the genetic implications for these conditions. The second part of this book will take us on a philosophical journey into the world of the mind. We'll explore debates about the nature of consciousness, the mind-body problem, reductionism, and dualism. We will investigate the relationship between the mind and the brain, the question of personal identity over time, and the philosophical implications of the mind in relation to artificial intelligence, free will, neuroscience, qualia, and even animal consciousness.
Synthetic Biology Genetics And Advanced Topics
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
Synthetic Biology Genetics And Advanced Topics written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Health & Fitness categories.
Synthetic Biology is a scientific discipline that has the potential to revolutionize the way we understand and manipulate life. Combining knowledge from biology, genetics, engineering and computing, Synthetic Biology opens up new possibilities for creating personalized biological systems, with applications ranging from regenerative medicine to the production of biofuels. In this book, we will explore the principles, techniques, and applications of synthetic biology, with the aim of providing a comprehensive and up-to-date overview of this ever-evolving field. Throughout the chapters, we will delve into the molecular foundations of Synthetic Biology, exploring the biological components and processes involved in building synthetic biological systems. We will present several applications of Synthetic Biology in different sectors, highlighting its role in the pharmaceutical industry, in the production of biofuels, in the development of personalized vaccines and in regenerative medicine. We will see how the manipulation of synthetic stem cells can revolutionize the area of tissue regeneration and how metabolic engineering allows us to design microorganisms capable of producing valuable compounds. Bioinformatics plays a crucial role in Synthetic Biology, and we will dedicate a chapter to exploring how the analysis of genomic data and the use of bioinformatics algorithms contribute to the advancement of this discipline. In addition, we will cover topics such as genome editing using CRISPR technology, synthetic protein engineering, and directed evolution in the laboratory. With the advancement of technology, it has become possible to manufacture living tissue in the laboratory, and we will discuss biofabrication and 3D printing of living tissue, as well as the use of microfluidics in the manipulation and analysis of synthetic biological systems on a microscopic scale. We will also address ethical and biosafety issues related to Synthetic Biology, recognizing the importance of a responsible approach in all its applications. This book is intended for students, researchers, and practitioners interested in exploring the frontiers of synthetic biology. We hope it will be an inspiring source of knowledge, awakening the curiosity and innovative spirit of all readers. We invite you to embark on this exciting journey through Synthetic Biology, in search of a deeper understanding of life and its transformative possibilities.
Heritable Human Genome Editing
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Author : The Royal Society
language : en
Publisher: National Academies Press
Release Date : 2021-01-16
Heritable Human Genome Editing written by The Royal Society and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-16 with Medical categories.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Advances In Biotechnology
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Author : Indu Ravi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-21
Advances In Biotechnology written by Indu Ravi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-21 with Science categories.
The book “Advances in Biotechnology” is about recent advances in some of the important fields that are ongoing in certain biotechnological applications. Biotechnology has been quite helpful in keeping pace with the demands of every increasing human population and in improving the quality of human life. Major biotechnological achievements associated with human welfare have been from the fields like genetic engineering; transgenic plants and animals; genomics, proteomics, monoclonal antibodies for the diagnosis of disease, gene therapy etc. Fourteen authoritative chapters written by experts having experience in academics and research on current developments and future trends in biotechnology have been empathized. The book provides a detailed account of various methodologies used in biotechnology i.e. High capacity vectors, DNA sequencing dealing with next generation sequencing, Molecular markers, DNA microarray technology, as well as Proteomics that have revolutionized biotechnology with a wide array of applications. The book not only presents a well-founded explanation of the topics but also aims to present up-to-date reviews of current research efforts, some thoughtful discussions on the potential benefits and risks involved in producing biotechnological products and the challenges of bringing such products to market. It will prove to be an excellent reference work for both academicians and researchers, indicating new starting points to young researchers for new projects in the field. The book is intended for biotechnologist, biologist, researchers, teachers and students of Biosciences and Biotechnology.
Introduction To Synthetic Embryology
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
Introduction To Synthetic Embryology written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Health & Fitness categories.
In the current era, in which science and technology are advancing by leaps and bounds, we are witness to discoveries and achievements that challenge us to rethink our understanding of life, health and human potential. Remarkable advances in the area of synthetic embryology and gene therapy have been the protagonists of a scientific revolution that takes us beyond the limits of what we previously imagined to be possible. In this book, we explore a vast territory of knowledge, delving into the fascinating domains of creation and modification of living beings, genetic manipulation and embryonic development. The aim is to offer the reader a panoramic and reflective view of the most recent advances in these areas, while raising crucial questions about ethical limits and the ethical and social challenges that accompany these discoveries. Throughout these pages, we delve into the development of gene therapies aimed at combating immune and muscle disorders, delving into the heart of personalized medicine and pointing to a future in which we can correct genetic defects even before birth. We also explore the frontiers between natural embryology and synthetic embryology, confronting traditional conceptions about the beginning of life and the revolutionary possibilities that arise from the manipulation of the fundamental mechanisms of embryonic development. With equal enthusiasm, we examine the applications of synthetic embryology in fields as diverse as creating transgenic foods, adapting organisms to hostile environments, understanding extraterrestrial life, and even colonizing other planets. In doing so, we are confronted with ethical and social dilemmas, the answers to which have the potential to shape not only science, but humanity itself. In each chapter, we seek to present a comprehensive and up-to-date view of scientific and technological advances, always accompanied by a critical and reflective analysis of the ethical implications and challenges we face. Our aim is to provide readers with a starting point for understanding these findings and for informed and constructive debate about the future of synthetic embryology and its implications for society. Therefore, I invite you, dear reader, to embark on this journey of discovery and reflection. As we enter this exciting, uncharted territory of synthetic embryology, we are confronted with profound and provocative questions about the nature of life, our own limits, and the responsibility we carry as custodians of science and innovation. This book is an invitation to explore the frontiers of science and ethics, to challenge our ingrained perceptions and conceptions and, above all, to ponder the future we wish to build. Embark on this journey with us and discover the intriguing and disturbing possibilities that synthetic embryology holds for us.
Advances In Animal Genomics
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Author : Sukanta Mondal
language : en
Publisher: Academic Press
Release Date : 2020-11-25
Advances In Animal Genomics written by Sukanta Mondal and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Science categories.
Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. - Integrates basic and advanced concepts of animal biotechnology and presents future developments - Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production - Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock - Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion
Genomic And Epigenomic Biomarkers Of Toxicology And Disease
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Author : Saura C. Sahu
language : en
Publisher: John Wiley & Sons
Release Date : 2022-04-21
Genomic And Epigenomic Biomarkers Of Toxicology And Disease written by Saura C. Sahu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-21 with Science categories.
Genomic and Epigenomic Biomarkers of Toxicology and Disease The latest developments in biomarker research applicable to toxicology and medicine Research on genomic and epigenomic biomarkers is developing rapidly with cutting-edge studies scattered throughout the academic literature, making the status of ongoing scientific activity in this area difficult to ascertain. Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions delivers a comprehensive and authoritative compilation of up-to-date developments in the application of genomic and epigenomic biomarkers to toxicology, disease prevention, cancer detection, therapeutics, gene therapy, and other areas. With contributions from a collection of internationally recognized investigators, this edited volume offers unique insights into current trends and future directions of research in the discussed areas. Combining state-of-the-art information on genomic and epigenomic biomarkers from a range of specialists from around the world, this monograph includes: A thorough introduction to microRNAs as non-invasive biomarkers of toxicity and chemical hazard Comprehensive explorations of extracellular vesicle-associated miRNAs as toxic biomarkers, as well as transcriptomic applications in toxicology and medicine Practical discussions of circulating miRNAs as biomarkers of metal exposure, as well as microRNAs biomarkers of malignant mesothelioma In-depth examinations of the role of noncoding RNAs in innate immune responses perturbed by environmental arsenic with a focus on microRNAs Perfect for researchers, toxicologists, risk assessors, and regulators, Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions will also earn a place in the libraries of graduate students with an interest in biomarkers, toxicology, agriculture, or the environment.
Drosophila Models For Human Diseases
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Author : Masamitsu Yamaguchi
language : en
Publisher: Springer
Release Date : 2018-06-27
Drosophila Models For Human Diseases written by Masamitsu Yamaguchi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with Medical categories.
Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.
Advances In Poultry Genetics And Genomics
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Author : Professor Sammy Aggrey
language : en
Publisher: Burleigh Dodds Science Publishing
Release Date : 2020-07-21
Advances In Poultry Genetics And Genomics written by Professor Sammy Aggrey and has been published by Burleigh Dodds Science Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-21 with Technology & Engineering categories.
Particular focus on improving functional traits needed for more resilient poultry breeds Comprehensive coverage of key advances in genomic selection and their practical application in breeding improved breeds of layers and broilers Looks forward to emerging trends such as the use of epigenetics and genome editing