Advances In Ion Mobility Mass Spectrometry Fundamentals Instrumentation And Applications
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Advances In Ion Mobility Mass Spectrometry Fundamentals Instrumentation And Applications
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Author :
language : en
Publisher: Elsevier
Release Date : 2019-01-10
Advances In Ion Mobility Mass Spectrometry Fundamentals Instrumentation And Applications written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-10 with Science categories.
Ion Mobility Spectrometry, Volume 83 will focuses on new trends, methods and instrumentation in the field, starting from the innovations of each technique, to the most progressive challenges of IM-MS. Chapters includes section on Recent advances in IM-MS, IM-MS Principles and Theory, IM-MS Applications and Instrumentation, and the Future of IM-MS. - Presents the latest advancements in IM-MS that are essential for new applications - Helps readers understand the state-of-the-art in the currently available IM-MS interfaces and their principle uses - Provides information on different IM-MS instrumentation - Delves into key applications of IM-MS
Ion Mobility Mass Spectrometry
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Author : Alison E Ashcroft
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-11-11
Ion Mobility Mass Spectrometry written by Alison E Ashcroft and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-11 with Science categories.
Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.
Ion Mobility Spectrometry Mass Spectrometry
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Author : Charles L. Wilkins
language : en
Publisher: CRC Press
Release Date : 2010-12-14
Ion Mobility Spectrometry Mass Spectrometry written by Charles L. Wilkins and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-14 with House & Home categories.
The analytical power of ion mobility spectrometry-mass spectrometry (IMS-MS) instruments is poised to advance this technology from research to analytical laboratories. Exploring these developments at this critical juncture, Ion Mobility Spectrometry-Mass Spectrometry: Theory and Applications covers the tools, techniques, and applications involved when molecular size and shape information is combined with the well-known analytical advantages of high-performance mass spectrometry. One of the Most Exciting Developments in Contemporary Mass Spectrometry After presenting an overview chapter and the fundamentals, the book focuses on instrumentation and ionization sources. It describes an ion-mobility-capable quadrupole time-of-flight mass spectrometer, the differential mobility analyzer, a cryogenic-temperature ion mobility mass spectrometer, the atmospheric solids analysis probe method, and laserspray ionization. In the final applications-oriented chapters, the contributors explore how homebuilt and commercial instruments using electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) methods are employed to solve biological and synthetic issues. Harness the Power of IMS-MS for Analyzing Complex Substances This work helps readers unfamiliar with IMS-MS to understand its fundamental theory and practical applications. It also encourages them to investigate the potential analytical uses of IMS-MS and further explore the power of this method. Numerous color figures are included on downloadable resources.
Electrospray And Maldi Mass Spectrometry
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Author : Richard B. Cole
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-26
Electrospray And Maldi Mass Spectrometry written by Richard B. Cole and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-26 with Science categories.
Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.
Portable Spectroscopy And Spectrometry Applications
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Author : Richard A. Crocombe
language : en
Publisher: John Wiley & Sons
Release Date : 2021-04-26
Portable Spectroscopy And Spectrometry Applications written by Richard A. Crocombe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-26 with Science categories.
The most comprehensive resource available on the many applications of portable spectrometers, including material not found in any other published work Portable Spectroscopy and Spectrometry: Volume Two is an authoritative and up-to-date compendium of the diverse applications for portable spectrometers across numerous disciplines. Whereas Volume One focuses on the specific technologies of the portable spectrometers themselves, Volume Two explores the use of portable instruments in wide range of fields, including pharmaceutical development, clinical research, food analysis, forensic science, geology, astrobiology, cultural heritage and archaeology. Volume Two features contributions by a multidisciplinary team of experts with hands-on experience using portable instruments in their respective areas of expertise. Organized both by instrumentation type and by scientific or technical discipline, 21 detailed chapters cover various applications of portable ion mobility spectrometry (IMS), infrared and near-infrared (NIR) spectroscopy, Raman and x-ray fluorescence (XRF) spectroscopy, smartphone spectroscopy, and many others. Filling a significant gap in literature on the subject, the second volume of Portable Spectroscopy and Spectrometry: Features a significant amount of content published for the first time, or not available in existing literature Brings together work by authors with assorted backgrounds and fields of study Discusses the central role of applications in portable instrument development Covers the algorithms, calibrations, and libraries that are of critical importance to successful applications of portable instruments Includes chapters on portable spectroscopy applications in areas such as the military, agriculture and feed, hazardous materials (HazMat), art conservation, and environmental science Portable Spectroscopy and Spectrometry: Volume Two is an indispensable resource for developers of portable instruments in universities, research institutes, instrument companies, civilian and government purchasers, trainers, operators of portable instruments, and educators and students in portable spectroscopy courses.
Alpha 1 Antitrypsin
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Author : Cynthia L. Bristow
language : en
Publisher: Springer Nature
Release Date : 2023-12-18
Alpha 1 Antitrypsin written by Cynthia L. Bristow and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-18 with Science categories.
This volume provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Alpha-1 Antitrypsin: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Screening Of Pollutants In The Environment
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Author : Miren López de Alda
language : en
Publisher: Springer Nature
Release Date : 2025-08-11
Screening Of Pollutants In The Environment written by Miren López de Alda and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-11 with Science categories.
This book reviews the latest advances in mass spectrometry for detecting environmental pollutants. With high-resolution mass spectrometry instruments becoming more accessible in research labs, scientists can now expand their analytical capabilities, establishing non-target strategies to identify priority pollutants and uncover new potentially hazardous compounds in various environmental compartments. In this book, readers will find a range of critical topics, including the use of ion mobility as a third dimension for compound confirmation in environmental samples, and the integration of high-resolution mass spectrometry analysis with market data to prioritize environmental contaminants. The book also explores effect-directed methods combined with non-target screening for identifying toxic transformation products, and the combination of passive sampling with non-target analysis for comprehensive environmental assessments. Additionally, it covers screening strategies for disinfection byproducts in drinking water and the human chemical exposome, providing insights into the quantitation of non-target data and the discovery of transformation byproducts of emerging contaminants. Given its breadth, this book is an essential resource for scientists addressing environmental pollution, students and academics in environmental analytical chemistry, and researchers focused on water, soil, and air studies. Environmental managers and engineers designing novel pollution remediation systems will find innovative strategies to advance their work. By focusing on priority pollutants and novel screening strategies, this book equips readers with the knowledge to tackle pressing environmental challenges.
Electrospray Ionization Mass Spectrometry
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Author : Richard B. Cole
language : en
Publisher: Wiley-Interscience
Release Date : 1997-05-06
Electrospray Ionization Mass Spectrometry written by Richard B. Cole and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-06 with Science categories.
Comprehensive, up-to-date coverage of a revolutionary technique Electrospray ionization mass spectrometry (ESI-MS) has completely changed the way physicists, chemists, and biologists view the study of large molecules. The technique derives detailed information about molecular weights and structures from extremely small sample quantities. ESI-MS can create highly charged forms of very high molecular weight compounds, it is naturally compatible with many types of separation techniques, and it allows noncovalent interactions between molecules in solution to be preserved in the gas phase. But many researchers may not use the technique to its full potential because they are unfamiliar with the different perspectives of its underlying processes, the varied approaches to implementation, and the wide-ranging utility of the technique. In this book, Richard B. Cole and an assemblage of leading researchers present a single-volume compilation of different approaches to the understanding and exploitation of ESI-MS. This comprehensive guide: * Examines the physical and chemical aspects of the electrospray process and describes the events involved in ion formation as well as the electro-chemical phenomena that are central to charged droplet formation during the process * Explores the coupling of electrospray ionization to various mass spectrometers, including quadrupole, magnetic, time-of-flight, quadrupole ion trap, and Fourier transform ion cyclotron resonance instruments * Describes recent progress in interfacing ESI with solution-based separation techniques, including liquid chromatography and capillary electrophoresis * Charts the rapid development of ESI applications and categorizes them by compound type: peptides and proteins, nucleic acids and their constituents, carbohydrates and lipids, small molecules related to pharmacology and drug metabolism, and organometallics and inorganic compounds Electrospray Ionization Mass Spectrometry is the indispensable handbook and reference for anyone who wishes to understand, implement, or apply this technique, including researchers in chemistry, metallochemistry, biochemistry, biology, pharmacology, and physics.
Advances In Food Analysis
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Author : Alessandra Gentili
language : en
Publisher: MDPI
Release Date : 2019-11-11
Advances In Food Analysis written by Alessandra Gentili and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Science categories.
This Topical Collection of Molecules provides the most recent advancements and trends within the framework of food analysis, confirming the growing public, academic, and industrial interest in this field. The articles broach topics related to sample preparation, separation science, spectroscopic techniques, sensors and biosensors, as well as investigations dealing with the characterization of macronutrients, micronutrients, and other biomolecules. It offers the latest updates regarding alternative food sources (e.g., algae), functional foods, effects of processing, chiral or achiral bioactive compounds, contaminants, and every topic related to food science that is appealing to readers. Nowadays, the increasing awareness of the close relation among diet, health, and social development is stimulating demands for high levels of quality and safety in agro-food production, as well as new studies to fill gaps in the actual body of knowledge about food composition. For these reasons, modern research in food science and human nutrition is moving from classical methodologies to advanced instrumental platforms for comprehensive characterization. Nondestructive spectroscopic and imaging technologies are also proposed for food process monitoring and quality control in real time.
Practical Aspects Of Trapped Ion Mass Spectrometry Volume Iv
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Author : Raymond E. March
language : en
Publisher: CRC Press
Release Date : 2010-05-25
Practical Aspects Of Trapped Ion Mass Spectrometry Volume Iv written by Raymond E. March and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-25 with Science categories.
Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapp