Advances In Single Molecule Real Time Smrt Sequencing

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Advances In Single Molecule Real Time Smrt Sequencing

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Author : Adam Ameur
language : en
Publisher: MDPI
Release Date : 2019-11-18

Advances In Single Molecule Real Time Smrt Sequencing written by Adam Ameur and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-18 with Science categories.

PacBio’s single-molecule real-time (SMRT) sequencing technology offers important advantages over the short-read DNA sequencing technologies that currently dominate the market. This includes exceptionally long read lengths (20 kb or more), unparalleled consensus accuracy, and the ability to sequence native, non-amplified DNA molecules. From fungi to insects to humans, long reads are now used to create highly accurate reference genomes by de novo assembly of genomic DNA and to obtain a comprehensive view of transcriptomes through the sequencing of full-length cDNAs. Besides reducing biases, sequencing native DNA also permits the direct measurement of DNA base modifications. Therefore, SMRT sequencing has become an attractive technology in many fields, such as agriculture, basic science, and medical research. The boundaries of SMRT sequencing are continuously being pushed by developments in bioinformatics and sample preparation. This book contains a collection of articles showcasing the latest developments and the breadth of applications enabled by SMRT sequencing technology.

Advances In Single Molecule Real Time Smrt Sequencing

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Author : Adam Ameur
language : en
Publisher:
Release Date : 2019

Advances In Single Molecule Real Time Smrt Sequencing written by Adam Ameur and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Biology (General) categories.

PacBio's single-molecule real-time (SMRT) sequencing technology offers important advantages over the short-read DNA sequencing technologies that currently dominate the market. This includes exceptionally long read lengths (20 kb or more), unparalleled consensus accuracy, and the ability to sequence native, non-amplified DNA molecules. From fungi to insects to humans, long reads are now used to create highly accurate reference genomes by de novo assembly of genomic DNA and to obtain a comprehensive view of transcriptomes through the sequencing of full-length cDNAs. Besides reducing biases, sequencing native DNA also permits the direct measurement of DNA base modifications. Therefore, SMRT sequencing has become an attractive technology in many fields, such as agriculture, basic science, and medical research. The boundaries of SMRT sequencing are continuously being pushed by developments in bioinformatics and sample preparation. This book contains a collection of articles showcasing the latest developments and the breadth of applications enabled by SMRT sequencing technology.

Next Generation Sequencing

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Author : Jerzy Kulski
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-01-14

Next Generation Sequencing written by Jerzy Kulski and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Medical categories.

Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

Advances In Bioinformatics

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Author : Vijai Singh
language : en
Publisher: Springer Nature
Release Date : 2024-02-05

Advances In Bioinformatics written by Vijai Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-05 with Computers categories.

The second edition of Advances in Bioinformatics presents the latest developments in bioinformatics in gene discovery, genome analysis, genomics, transcriptomics, proteomics, metabolomics, metabolic flux analysis, drug discovery, and drug repurposing. It includes advancements in the applications of bioinformatics in the analysis of non-coding RNA, next-generation sequencing, genome-scale modelling, high throughput drug screening, precision medicine, automation and artificial intelligence, and machine learning. The chapter also summarizes the technologies and concepts that form the basis of this functional genomics approach. Additionally, the book highlights some of the areas in which bioinformatics resources and methods are being developed to support the drug discovery pipeline. The chapter also discusses the role of bioinformatics in modelling and simulations of molecular biology systems in pathways identification and design. It is a valuable source of information for beginners in bioinformatics and students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in biomedical and allied sciences.

Precision Medicine

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Author : Hans-Peter Deigner
language : en
Publisher: Academic Press
Release Date : 2018-02-15

Precision Medicine written by Hans-Peter Deigner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-15 with Medical categories.

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. - Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods - Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation - Encompasses easy access to relevant approaches, interactions and original literature

Next Generation Sequencing

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Author : Lee-Jun C. Wong
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-31

Next Generation Sequencing written by Lee-Jun C. Wong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-31 with Medical categories.

In recent years, owing to the fast development of a variety of sequencing technologies in the post human genome project era, sequencing analysis of a group of target genes, entire protein coding regions of the human genome, and the whole human genome has become a reality. Next Generation Sequencing (NGS) or Massively Parallel Sequencing (MPS) technologies offers a way to screen for mutations in many different genes in a cost and time efficient manner by deep coverage of the target sequences. This novel technology has now been applied to clinical diagnosis of Mendelian disorders of well characterized or undefined diseases, discovery of new disease genes, noninvasive prenatal diagnosis using maternal blood, and population based carrier testing of severe autosomal recessive disorders. This book covers topics of these applications, including potential limitations and expanded application in the future. ​

Advances In Molecular Pathology

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Author : Gregory J. Tsongalis
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-11-01

Advances In Molecular Pathology written by Gregory J. Tsongalis and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-01 with Medical categories.

Advances in Molecular Pathology reviews the year's most important findings and updates within the field in order to provide molecular pathologists with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Gregory Tsongalis, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in molecular pathology inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care. - Provides in-depth, clinical reviews in molecular pathology, providing actionable insights for clinical practice. - Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

One Carbon Group Transferases Advances In Research And Application 2012 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

One Carbon Group Transferases Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.

One-Carbon Group Transferases—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about One-Carbon Group Transferases. The editors have built One-Carbon Group Transferases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about One-Carbon Group Transferases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of One-Carbon Group Transferases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Metagenomics For Microbiology

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Author : Jacques Izard
language : en
Publisher: Academic Press
Release Date : 2025-09-01

Metagenomics For Microbiology written by Jacques Izard and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-09-01 with Science categories.

Metagenomics for Microbiology, Second Edition unveils the intricate and diverse world of microbial communities, emphasizing their critical roles in health, disease, and ecosystem functionality. This updated edition addresses the significant challenges in the field and introduces promising approaches to make metagenomics research more feasible. Through comprehensive revisions and over five new chapters, readers are equipped with the latest research data and analyses, advancing their understanding of microbial principles. Notably, this edition provides a robust foundation for the design and analysis of omics studies, focusing on technological underpinnings and practical applications. It remains an essential resource for characterizing microbial consortia. - Describes updated methodologies with best-practice prescription, from sample to data analysis, for current metagenomic studies - Updates on sample preparation, data production, data clean up, data analysis, statistics, and experimental biology, with accompanying descriptions - Includes a new chapter on long read applications using Nanopore technology - Provides a new chapter on probability distributions that underpin the structure of microbiome ecosystems - Covers bio surveillance of diseases and biodefense

Advances In Forensic Biology And Genetics

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Author : Hirak Ranjan Dash
language : en
Publisher: Springer Nature
Release Date : 2025-05-15

Advances In Forensic Biology And Genetics written by Hirak Ranjan Dash and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-15 with Medical categories.

The book explores the interdisciplinary field that merges biochemistry, cell biology, molecular biology, and genetics to unravel the mysteries of biological evidence in forensic investigations. Delving into the core of this dynamic discipline, the book unveils how forensic biological scientists leverage a diverse range of techniques to address complex questions posed by investigative agencies. The book meticulously covers different facets of forensic biology, from uncovering the origins of crucial body fluids to predicting the post-mortem time interval, while deciphering the cause and manner of death to individualizing biological samples. This book consolidates the latest breakthroughs in forensic biology and genetics, embracing both human and non-human DNA analyses, helpful for the forensic biological scientists. Chapters are written by researchers and practitioners from around the world. This book serves as an indispensable resource for investigating officers, forensic scientists, medical practitioners, researchers, and students.