Advances In Skeletal Reconstruction Using Bone Morphogenetic Proteins
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Advances In Skeletal Reconstruction Using Bone Morphogenetic Proteins
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Author : T. Sam Lindholm
language : en
Publisher: World Scientific
Release Date : 2002
Advances In Skeletal Reconstruction Using Bone Morphogenetic Proteins written by T. Sam Lindholm and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The bone morphogenetic protein (BMP) is a special growth factor for the induction of new bone formation. Today, the extract of the BMP originating from bone tissue as well as genetically modified BMPs, particularly BMP-2 and -7, can be used.Though the BMP as an implant is as yet an unregistered drug or medical tool in Europe and the US, specialists are confident that it will obtain final government approval based on the results of clinical tests conducted on more than 3000 patients.This important book focuses mainly on the clinical BMP treatment of patients OCo namely in orthopaedic cases (fractures, bone transplants, non-unions and pseudoarthroses), maxillofacial surgery (sinus lift before dental implantation), dental surgery (filling out of cavities) and spinal surgery (using a BMP implant instead of the patient's own bone)."
Bone Morphogenetic Proteins
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Author : Slobodan Vukicevic
language : en
Publisher: Springer
Release Date : 2012-11-28
Bone Morphogenetic Proteins written by Slobodan Vukicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Science categories.
From the basic science to potential and approved clinical applications the most recent data in the rapidly growing field of bone morphogenetic proteins (BMPs) are summarized in this topical volume. Distinguished scientists present reviews on a range of scientific topics, including biochemistry, biology, molecular biology and preclinical animal studies on spinal fusion, cartilage repair, craniofacial and dental reconstruction using BMPs, as well as approved clinical applications in human bone non-unions. This book provides a resource not only for experts in the field, but also for undergraduate students, newcomers and clinicians worldwide, given that the use of BMPs in orthopedic reconstruction has been already approved in Europe, Australia, Canada and the USA.
Bone Morphogenetic Proteins Regeneration Of Bone And Beyond
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Author : Slobodan Vukicevic
language : en
Publisher: Springer
Release Date : 2012-11-28
Bone Morphogenetic Proteins Regeneration Of Bone And Beyond written by Slobodan Vukicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Science categories.
Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific discoveries and clinical reports on their use from institutions all over the world. The potent effica cy of BMPs in almost all crucial developmental events as well as during regenera tion of various organs such as bone, kidney, brain, liver, heart etc. , has positioned BMPs at the center of scientific interest. Many of these aspects are covered in this new PIR volume. Their role in development, biology, signal transduction, kidney regeneration, eNS functions, craniofacial skeleton reconstruction, joint and carti lage repair, long bone non-unions and acute fractures, and spinal fusion is reviewed by experts in the field. For the first time, the role of BMPs in carcinogenesis has been reviewed to provide a rationale for applying their biology in patients with bone tumors. The optimism resulting from safe and successful treatment with BMPs for various skeletal malformations of more than 10,000 patients worldwide has opened new avenues for exploring other indications for their use. The next big challenge for bringing BMPs to the benefit ofmankind is in regenerating articular cartilage defects and rescuing patients with acute and chronic renal failure. The volume editors thank all authors for the rapid preparation of their chapters in order that the book remains up-to-date for readers with specific interest in the field of regenerative medicine. The important contribution of Mrs. Morana and Mr.
Advances In Skeletal Reconstruction Using Bone Morphogenetic Proteins
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Author : T Sam Lindholm
language : en
Publisher: World Scientific
Release Date : 2002-06-04
Advances In Skeletal Reconstruction Using Bone Morphogenetic Proteins written by T Sam Lindholm and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-04 with Medical categories.
The bone morphogenetic protein (BMP) is a special growth factor for the induction of new bone formation. Today, the extract of the BMP originating from bone tissue as well as genetically modified BMPs, particularly BMP-2 and -7, can be used. Though the BMP as an implant is as yet an unregistered drug or medical tool in Europe and the US, specialists are confident that it will obtain final government approval based on the results of clinical tests conducted on more than 3000 patients. This important book focuses mainly on the clinical BMP treatment of patients — namely in orthopaedic cases (fractures, bone transplants, non-unions and pseudoarthroses), maxillofacial surgery (sinus lift before dental implantation), dental surgery (filling out of cavities) and spinal surgery (using a BMP implant instead of the patient's own bone). Contents:Induction of Osteogenic Potential of Fibroblasts by Transfection of rhBMP-2 (X Si et al.)Determination of the Biological Activity of BMP in Cell Cultures is Unreliable (M Ulmanen et al.)Different Configurations of Bioactive Silica Glass as Carrier for BMP (T C Lindholm)Developing a Bioimplant of Coral and Extracted BMP for Clinical Use (T S Lindholm et al.)Exogenous and Endogenous OP-1 in Articular Cartilage (S Chubinskaya & K E Kuettner)Effect of BMP Around Dental Implant (K Bessho & J L Ong)Mandibular Reconstruction Using Naturally Derived BMPs: A Clinical Trial Report (U Ripamonti & C Ferretti)BMPs in Oral Clinical Application (E Lourenco)The Use of OP-1 in Resistant Pseudoarthrosis: Eight Case Reports (G H G Dekkers et al.)Fractures of the Thoracolumbar Spine and Prospects of Consecutive Spinal Fusion Enhancement by Means of BMP (T R Blattert)and other papers Readership: Researchers in the fields of growth factors, biomaterials and genetics, as well as dentists, orthopaedic, maxillofacial and spinal surgeons. Keywords:Skeletal Reconstruction;Bone Morphogenetic Proteins-Extraxts and Recombinants;Fracture Repair;Delayed Bone Union;Bone Lenghtening;Dental Implants;Bone Defects;Spinal Fusion;Cartilage Repair;Mandibular-Maxillar and Skull Defects
Biomechanics And Biomaterials In Orthopedics
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Author : Dominique G. Poitout
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-07-02
Biomechanics And Biomaterials In Orthopedics written by Dominique G. Poitout and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-02 with Medical categories.
Current clinical orthopedic practice requires practitioners to have extensive knowledge of a wide range of disciplines from molecular biology to bioengineering and from the application of new methods to the evaluation of outcome. The biomechanics of and biomaterials used in orthopedics have become increasingly important as the possibilities have increased to treat patients with foreign material introduced both as optimized osteosynthesis after trauma and as arthroplasties for joint diseases, sequelae of trauma or for tumor treatment. Furthermore, biomaterial substitutes are constantly being developed to replace missing tissue. Biomechanics and Biomaterials in Orthopedics provides an important update within this highly important field. Professor Dominique Poitout has collected a series of high-quality chapters by globally renowned researchers and clinicians. Under the auspices of the International Society of Orthopaedic Surgery and Traumatology (SICOT) and International Society of Orthopaedic and Traumatology Research (SIROT), this book now provides permanent and specific access to the considerable international knowledge in the field of locomotor system trauma and disease treatment using the novel bioengineering solutions. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also provide an important basis for graduate and postgraduate learning.
Induction Of Bone Formation In Primates
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Author : Ugo Ripamonti
language : en
Publisher: CRC Press
Release Date : 2015-10-02
Induction Of Bone Formation In Primates written by Ugo Ripamonti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-02 with Medical categories.
The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta (β) isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor-β3 sums up editor Ugo Ripamonti’s research into the osteogenic activity of the three mammalian TGF-β isoforms, particularly in primates. It explores how the mammalian TGF-β isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book unearths the profound and important bone inductive activity of the TGF-β3 isoform. It includes accounts of extensive research in non-human primates from craniofacial tissue regeneration, heterotopic tissue induction, and chapters on periodontal tissue regeneration and synergistic induction of bone formation. It also discusses the future clinical role of the TGF-β isoform, including in human studies. This book contributes to the fascinating history of BMP and TGF-β research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.
Pharmaceutical Biotechnology
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Author : Oliver Kayser
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Pharmaceutical Biotechnology written by Oliver Kayser and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
With its focus on industrial pharmaceutical research, written by international experts from the industry, this book fills in a gap in the existing literature. It reflects the combination of such pharmaceutical interests as drug delivery, drug targeting, quality and safety management, drug approval and regulation, patenting issues and biotechnology fundamentals. Thus it provides practitioners in pharmaceutical biotechnology with all the relevant information from the shelf. The first part offers a comprehensive survey and review of the rapidly increasing array of biopharmaceuticals derived from the molecular biological approaches now widely available. This is followed by an extra section devoted to the very critical patenting and drug regulation issues. The whole is rounded off by detailed monographs of biotechnologically developed drugs that are already on the market. With a foreword of by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at the Massachusetts Institute of Technology. In 2002, he received the Charles Stark Draper Prize, the highest recognition for an engineer. Professor Langer is member of all three national academies - the Institute of Medicine, the National Academy of Engineering, and the National Academy of Sciences: "The book attempts to provide a balanced view of the biotechnological industry and the number of experts from industry sharing their knowledge and experience with the audience gives the book an outstanding value. All contributors provide with each chapter an up-to-date review on key topics in pharmaceutical biotechnology. This work is not only a valuable tool for the industrial expert but also for all pharmacists and scientists from related areas who wish to work with biotech drugs."
Development Of New In Situ Hardening And Bioactivated Composite Materials For Orthopedic Indications
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Author : Cornelius Pompe
language : en
Publisher: Cuvillier Verlag
Release Date : 2008
Development Of New In Situ Hardening And Bioactivated Composite Materials For Orthopedic Indications written by Cornelius Pompe and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Bone Morphogenetic Proteins From Local To Systemic Therapeutics
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Author : Slobodan Vukicevic
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-15
Bone Morphogenetic Proteins From Local To Systemic Therapeutics written by Slobodan Vukicevic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-15 with Science categories.
Completing the PIR series, this volume summarizes the major advances made in the local and systemic use of bone morphogenetic proteins (BMPs). Chapters are dedicated to the regulation of BMP-signaling pathways; biological actions of BMPs in bone, cartilage, and teeth; clinical applications; and the potential systemic use of BMPs for tissues beyond bone. The authors are all recognized experts in the field of tissue engineering and regeneration.
Advanced Techniques In Bone Regeneration
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Author : Alessandro Rozim Zorzi
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-08-31
Advanced Techniques In Bone Regeneration written by Alessandro Rozim Zorzi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-31 with Medical categories.
Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.