Aging And Age Related Disorders
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Aging And Age Related Disorders
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Author : Stephen Bondy
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-02
Aging And Age Related Disorders written by Stephen Bondy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-02 with Medical categories.
Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.
Aging And Age Related Diseases
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Author : Michał Karasek
language : en
Publisher: Nova Publishers
Release Date : 2006
Aging And Age Related Diseases written by Michał Karasek and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Age factors in disease categories.
Ageing has become a great problem for many countries. Due to world-wide life prolongation the number of people over 6o years old has grown rapidly into a ten percent piece of the world population. The growing age of the world population raises many social, economical, and medical problems. The proportion of people in the economically active age groups to those who are over 65 is constantly decreasing. A major consequence of the increasing numbers of individuals in advanced age groups is increasing numbers of patients suffering from age-related diseases. The aim of this book is to present the basic data on human ageing as well as on age-related diseases.
Diseases In The Elderly
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Author : Nages Nagaratnam
language : en
Publisher: Springer
Release Date : 2016-02-25
Diseases In The Elderly written by Nages Nagaratnam and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-25 with Medical categories.
This book provides a comprehensive overview of the two important issues relating to disease in elderly: the age-related changes and the pathophysiology of the diseases. The book contains 19 chapters that are arranged by organ system and structured to cover the specific areas for a quick but in-depth understanding of diseases in aging patients. Unlike any other book on the market, this text is concise and yet thorough in approach to the stipulated areas. This book includes multiple-choice questions that reinforce the concepts that are most vital to understanding and treating geriatric patients, making it an outstanding resource on its own or as a companion to larger geriatric texts. Diseases in the Elderly is the ultimate resource for geriatricians, medical students, primary care physicians, hospital doctors, geriatric nurses, and all other medical professionals treating and diagnosing diseases in elderly patients.
Prevention And Treatment Of Age Related Diseases
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Author : Suresh I.S. Rattan
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-09
Prevention And Treatment Of Age Related Diseases written by Suresh I.S. Rattan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-09 with Medical categories.
This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. Employing a semi-academic style, the book presents data from experimental systems, while focusing primarily on their applications to humans in the prevention and treatment of age-related impairments.
Aging And Age Related Disorders From Molecular Mechanisms To Therapies
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Author : Vladimir Titorenko
language : en
Publisher: MDPI
Release Date : 2019-08-19
Aging And Age Related Disorders From Molecular Mechanisms To Therapies written by Vladimir Titorenko and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-19 with Science categories.
Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson’s, Alzheimer’s, and Huntington’s diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies.
Pharmacological Intervention In Aging And Age Associated Disorders
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Author : International Association of Biomedical Gerontology. International Congress
language : en
Publisher:
Release Date : 1996
Pharmacological Intervention In Aging And Age Associated Disorders written by International Association of Biomedical Gerontology. International Congress and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Family & Relationships categories.
This volume focuses primarily on potential interventions by pharmaceuticals, nutrients or chemicals in age-related disorders. Various experiments using deprenyl, melatonin, phenyl t-butyl nitrone, acidic fibroblast growth factor; and other compounds are reviewed, bringing these still controversial treatments to the attention of a wide variety of researchers. To develop new strategies for dealing with ageing there is extensive discussion of the mechanisms underlying the ageing process. This volume is of interest not only to basic scientists working in different fields of experimental gerontology, but also to clinicians who want to know what can be done to extend the functional life span of humans and animals by preventing the incidence and severity of age-related disorders.
Aging And Age Related Disorders From Molecular Mechanisms To Therapies
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Author : Vladimir Titorenko
language : en
Publisher:
Release Date : 2019
Aging And Age Related Disorders From Molecular Mechanisms To Therapies written by Vladimir Titorenko and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.
Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson's, Alzheimer's, and Huntington's diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies.
Molecular Mechanisms Of Skin Aging And Age Related Diseases
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Author : Taihao Quan
language : en
Publisher: CRC Press
Release Date : 2016-04-21
Molecular Mechanisms Of Skin Aging And Age Related Diseases written by Taihao Quan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.
Our skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation. The book also focuses on research to develop mechanisms-based anti-skin-aging products.
The Role Of Antioxidants In Longevity And Age Related Diseases
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Author : Bee Ling Tan
language : en
Publisher: Springer Nature
Release Date : 2021-11-19
The Role Of Antioxidants In Longevity And Age Related Diseases written by Bee Ling Tan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-19 with Family & Relationships categories.
The average life expectancy has increased worldwide in the recent decades. This has presented new challenges as old age brings the onset of diseases such as cancer, neurodegenerative disorders, cardiovascular disease, type 2 diabetes, arthritis, osteoporosis, stroke, and Alzheimer’s disease. Studies and research have shown the potential preventive and therapeutic roles of antioxidants in aging and age-related diseases by inhibiting the formation or disrupting the propagation of free radicals and thus increasing healthy longevity, enhancing immune function, and decreasing oxidative stress. This has made an antioxidant rich diet of increasing importance in battling the detrimental effects of the aging process. “The Role of Antioxidants in Longevity and Age-Related Diseases” is the book that compiles research on antioxidants and their biological mechanisms that mediate age-related diseases. This book covers the major issues linked to antioxidants, aging, and age-related diseases, including changes in organ systems over the lifespan, age-related oxidative stress-induced redox imbalance, inflammaging, implications of inflammation in aging and age-related diseases, and the important role of antioxidant-rich foods in their prevention and treatment of various age-related diseases. For researchers seeking a comprehensive single source on antioxidants and their roles in aging and age-related diseases, this novel text provides an up-to-date overview.
Handbook Of Mental Health And Aging
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Author : Nathan Hantke
language : en
Publisher: Academic Press
Release Date : 2020-04-11
Handbook Of Mental Health And Aging written by Nathan Hantke and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-11 with Psychology categories.
The Handbook of Mental Health and Aging, Third Edition provides a foundational background for practitioners and researchers to understand mental health care in older adults as presented by leading experts in the field. Wherever possible, chapters integrate research into clinical practice. The book opens with conceptual factors, such as the epidemiology of mental health disorders in aging and cultural factors that impact mental health. The book transitions into neurobiological-based topics such as biomarkers, age-related structural changes in the brain, and current models of accelerated aging in mental health. Clinical topics include dementia, neuropsychology, psychotherapy, psychopharmacology, mood disorders, anxiety, schizophrenia, sleep disorders, and substance abuse. The book closes with current and future trends in geriatric mental health, including the brain functional connectome, repetitive transcranial magnetic stimulation (rTMS), technology-based interventions, and treatment innovations. Identifies factors influencing mental health in older adults Includes biological, sociological, and psychological factors Reviews epidemiology of different mental health disorders Supplies separate chapters on grief, schizophrenia, mood, anxiety, and sleep disorders Discusses biomarkers and genetics of mental health and aging Provides assessment and treatment approaches