Alcohol Metabolism Alcohol Intolerance And Alcoholism
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Alcohol Metabolism Alcohol Intolerance And Alcoholism
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Author : Dharam P. Agarwal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Alcohol Metabolism Alcohol Intolerance And Alcoholism written by Dharam P. Agarwal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society. The purpose of this comprehensive monograph is to review the available knowledge concerning the pharmacogenetic basis of alcohol sensitivity and its physiolgical implications and to synthesize the bulk of existing knowledge regarding metabolic features and biomedical disturbances related to alcoholism. The chapters cover a broad array of disciplines including an overview of historical and epidemiological aspects, biochemistry and molecular genetics of enzymes involved in alcohol metabolism, biochemical and neuropsychopharmacological effects of alcohol. Major emphasis is placed on the role of genetic factors in alcoholism. The experimental details are summarized and a comprehensive bibliography is included.
Alcohol In Health And Disease
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Author : Dharam Agarwal
language : en
Publisher: CRC Press
Release Date : 2001-06-01
Alcohol In Health And Disease written by Dharam Agarwal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-01 with Medical categories.
This volume, based on presentations from the symposium on the health effects of alcohol held in Titisee, Germany, examines the physical and psychological consequences of alcohol use and abuse, and considers environmental and ethnic factors that lead to addiction and dependence. Discusses epidemiological studies that show the influence of light to moderate intake of alcoholic beverages on coronary heart disease. Featuring contributions from nearly 60 internationally recognized and respected authors, and over 2900 references for further investigation of the subject, Alcohol in Health and Disease analyzes biochemical, pharmacogenetic, and pathologic disturbances that follow acute and chronic ingestion of alcohol; describes complications that arise from social, biological, and environmental factors; examines alcohol metabolic genes and their role in alcohol sensitivity, drinking habits, and dependence; spotlights hepatic and nutritional disorders associated with alcoholism; considers the relationship of alcohol to cancer; debates the French paradox and more. Covering a multitude of disciplines, including molecular biochemistry, genetics, epidemiology, pathophysiology, neurobiology, and cardiology, Alcohol in Health and Disease is a critical reference for addiction psychiatrists, neuropsychopharmacologists, psychologists, geneticists, toxicologists, biochemists, environmental and public health scientists, health policy makers, social workers, counselors, and graduate and medical school students in these disciplines.
The Molecular Pathology Of Alcoholism
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Author : T. Norman Palmer
language : en
Publisher:
Release Date : 1991
The Molecular Pathology Of Alcoholism written by T. Norman Palmer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
The last few years have seen major advances in our understanding of the molecular and genetic events associated with alcohol abuse. The advent of recombinant DNA technology has allowed the structure of the genes and proteins of alcohol metabolism to be identified, and this work has formed the basis for genetic studies of factors that influence drinking behavior and alcoholism. This book provides an introduction for the non-specialist reader to recent developments concerning the molecular pathology of alcohol-related disease. It gives substance to the view that alcoholism is an organic disorder that stems from the specific interaction of alcohol and its metabolites with cellular components. Particular attention is paid to the molecular biology of the enzymes of alcohol metabolism.
Metabolic Aspects Of Alcoholism
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Author : Charles S. Lieber
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Metabolic Aspects Of Alcoholism written by Charles S. Lieber and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the first annual report on Alcohol and. Health to Congress (December, 1971), the then HEW Secretary Elliot L. Richardson called alcohol 'the most abused drug in the United States'. The report revealed that nine million Americans are alcohol abusers and that alcoholic individuals represent almost 10 % of the nation's work force. With spreading alcoholism, the incidence of physical damage due to alcohol has greatly increased. A question which is often raised is 'in which way does an alcoholic differ from a non-alcoholic?' Inquiries have focused on psychological make-up, behavioural differences and socioeconomic factors. More recently, however, physical differences have been delineated. Prior to the development of various disease entities, chronic ethanol exposure results in profound biochemical and morphological changes. Consequently an alcoholic does not respond normally to alcohol, or other drugs or even other toxic agents. Some of these persistent biochemical and morphological changes are the consequences of the injurious effects of ethanol, whereas others may represent the possible adaptive responses to the profound changes in intermediary metabolism which are a direct and im mediate consequence of the oxidation of ethanol itself. Differentiation between the effects of ethanol directly linked to its oxidation, and the adaptive and injurious effects of ethanol are not simple, and overlap is common. In general, however, metabolic effects are associated with the presence of relatively low ethanol concentrations, whereas injurious effects occur with high ethanol concentrations and/or after prolonged intake. High ethanol con centrations also produce so-called pharmacological effects.
Medical And Nutritional Complications Of Alcoholism
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Author : Charles S. Lieber
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Medical And Nutritional Complications Of Alcoholism written by Charles S. Lieber and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Psychology categories.
In the Western world, alcohol is the most abused drug. recognized that a majority of patients with cirrhosis do For all the attention being directed toward heroin, co admit to excessive alcohol consumption. Other tissues caine, and marijuana, the favorite mood-altering drug in can also be severely affected, including brain, gut, the United States, as in almost every human society, is heart, endocrine systems, bone, blood, and muscle. A question often raised is, "In what way does an alcoholic alcohol. In nature, the fermentation of sugars is the differ from a nonalcoholic?" Inquiries have focused on major source of ethanol, but how humans first encoun tered it is unclear. It most likely occurred in either psychological make-up, behavioral differences, and socio fermented fruit juices (wine), fermented grain (beer), or economic factors. More recently, however, physical dif fermented honey (mead). Whether the Paleolithic Stone ferences have been delineated. Prior to the development Age man knew of ethanol is undetermined, but it is of various disease entities, chronic ethanol exposure abundantly clear that his Neolithic descendants were results in profound biochemical and morphological familiar with the product of fermentation. With the changes. Consequently, an alcoholic does not respond exception of the original inhabitants of Tierra del Fuego, normally to alcohol, other drugs, or even other toxic the Australian aborigines, and some polar tribes, all agents.
Biological Aspects Of Alcoholism
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Author : Boris Tabakoff
language : en
Publisher:
Release Date : 1995
Biological Aspects Of Alcoholism written by Boris Tabakoff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Psychology categories.
Therefore this volume is invaluable for a wide range of treatment professionals, health care and law enforcement managers and policy makers, as well as for researchers involved with the biomedical and psychosocial consequences of alcoholism. Medically-oriented lay readers will also find this book to be a refreshingly direct and authoritative review of the field.
Alcohol Consumption And Alcoholism In Hungary
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Author : Dharam P. Agarwal
language : en
Publisher:
Release Date : 1997
Alcohol Consumption And Alcoholism In Hungary written by Dharam P. Agarwal and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
This volume grew out of a German-Hungarian collaborative research programme on alcohol and alcoholism carried out during the years 1990-93. One of the major objectives of this joint study was to explore the epidemiological and biomedical aspects of alcohol drinking and abuse in Hungary. There are indeed very few systematic surveys available in Hungary concerning these issues. The book covers a number of multidisciplinary topics such as epidemiology, biochemistry, pathophysiology, psychiatry, genetics, teratology, as well as environmental, socio-cultural and ethnic aspects of alcohol use and abuse in Hungary. The authors themselves have, in the past, contributed significantly to alcohol and alcoholism research as well as to population genetic aspects of the Hungarian population. This volume will prove particularly useful to basic scientists and physicians in the area of alcoholism research such as clinicians, geneticists, pharmacologists, toxicologists, psychiatrists, biochemists, environmental and public health scientists, and health policy makers.
Human Metabolism Of Alcohol Volume I
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Author : Kathryn E. Crow
language : en
Publisher: CRC Press
Release Date : 1989-04-30
Human Metabolism Of Alcohol Volume I written by Kathryn E. Crow and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-04-30 with Medical categories.
This three-volume text provides a comprehensive review and reference source for those with a teaching, research, or practical involvement in alcohol metabolism in humans. Written by 70 contributing authors from 12 countries, this publication covers a wide range of material, from medicolegal aspects of alcohol metabolism to the structure of enzymes involved in metabolizing alcohol. Although primarily concerned with human alcohol metabolism, information from animal experiments is included where it clarifies results of human studies, or where information for human subjects is not available.
The Genetics Of Alcoholism
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Author : Henri Begleiter
language : en
Publisher: Alcohol and Alcoholism
Release Date : 1995
The Genetics Of Alcoholism written by Henri Begleiter and has been published by Alcohol and Alcoholism this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Alcoholism categories.
This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.
Recent Advances In The Biology Of Alcoholism
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Author : Charles S. Lieber
language : en
Publisher: Psychology Press
Release Date : 1982
Recent Advances In The Biology Of Alcoholism written by Charles S. Lieber and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
This valuable book, written by eminent researchers, focuses on the exciting developments in the field of alcohol metabolism and alcohol-endocrine interactions. They contribute significantly to our understanding of the metabolism of ethanol and its effects on the body with comprehensive chapters on the heterogeneity of aldehyde dehydrogenase, alcohol-drug interactions, the pathogenesis of alcoholic liver disease, and more.