Algorithms For Sample Preparation With Microfluidic Lab On Chip
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Algorithms For Sample Preparation With Microfluidic Lab On Chip
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Author : Sukanta Bhattacharjee
language : en
Publisher: CRC Press
Release Date : 2022-09-01
Algorithms For Sample Preparation With Microfluidic Lab On Chip written by Sukanta Bhattacharjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-01 with Technology & Engineering categories.
Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip
Error Tolerant Biochemical Sample Preparation With Microfluidic Lab On Chip
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Author : Sudip Poddar
language : en
Publisher: CRC Press
Release Date : 2022-07-27
Error Tolerant Biochemical Sample Preparation With Microfluidic Lab On Chip written by Sudip Poddar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-27 with Technology & Engineering categories.
Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.
Microfluidic Lab On A Chip For Chemical And Biological Analysis And Discovery
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Author : Paul C.H. Li
language : en
Publisher: CRC Press
Release Date : 2005-11-01
Microfluidic Lab On A Chip For Chemical And Biological Analysis And Discovery written by Paul C.H. Li and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-01 with Science categories.
The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations, and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays and enzymatic assays. Originally conceived as a single chapter published in Ewing's Analytical Instrumentation, this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.
Walcom Algorithms And Computation
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Author : M. Sohel Rahman
language : en
Publisher: Springer Nature
Release Date : 2020-01-27
Walcom Algorithms And Computation written by M. Sohel Rahman and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-27 with Computers categories.
This book constitutes the refereed proceedings of the 14th International Conference on Algorithms and Computation, WALCOM 2020, held in Singapore in March/April 2020. The 23 full and 4 short papers presented were carefully reviewed and selected from 66 submissions. The papers focus on algorithmic graph theory and combinatorics, computational biology, computational geometry, data structures, experimental algorithm methodologies, graph algorithms, graph drawing, parallel and distributed algorithms, network optimization.
Microfluidics And Lab On A Chip
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Author : Andreas Manz
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-09-24
Microfluidics And Lab On A Chip written by Andreas Manz and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-24 with Science categories.
Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.
Fundamentals Of Microfluidics And Lab On A Chip For Biological Analysis And Discovery
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Author : Paul C.H. Li
language : en
Publisher: CRC Press
Release Date : 2010-02-24
Fundamentals Of Microfluidics And Lab On A Chip For Biological Analysis And Discovery written by Paul C.H. Li and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-24 with Medical categories.
Lab-on-a-chip technology permits us to make many important discoveries that can only be observed at the microscale or the nanoscale. Using this technology, biological and biochemical analyses translate into greater sensitivity, more accurate results, and more valuable findings. Authored by one of the field’s pioneering researchers, Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery focuses on all key aspects of microfluidic lab-on-a-chip technologies to offer an exceptionally cohesive overview of the science, its limitations, breakthroughs made over the years, and currently emerging advances. The book emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays, and enzymatic assays. The book includes more than 300 figures that depict novel chip functions and breakthroughs and 16 tables summarize materials and refer readers to additional resources. An appendix compiles extensive analytical applications from emerging and established research groups. Beginners in the field will find the book useful for navigating the vast literature related to the technology, while experienced researchers will rely on the compiled information for easy comparison and references for further study. Derived from the highly popular Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery (2006), this volume is also readily adaptable for classroom use. Problem sets in each chapter help students test their assimilation of the material and clarify challenging concepts. The book contains a comprehensive glossary, a complete index, and extensive references. A solutions manual is available with qualifying course adoption.
Micro Electrode Dot Array Digital Microfluidic Biochips
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Author : Zipeng Li
language : en
Publisher: Springer
Release Date : 2018-12-14
Micro Electrode Dot Array Digital Microfluidic Biochips written by Zipeng Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-14 with Technology & Engineering categories.
This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.
Lab On A Chip Fabrication And Application
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Author : Margarita Stoytcheva
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-29
Lab On A Chip Fabrication And Application written by Margarita Stoytcheva and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-29 with Science categories.
The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.
Algorithms And Complexity
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Author : Pinar Heggernes
language : en
Publisher: Springer
Release Date : 2019-05-20
Algorithms And Complexity written by Pinar Heggernes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-20 with Computers categories.
This book constitutes the refereed conference proceedings of the 11th International Conference on Algorithms and Complexity, CIAC 2019, held in Rome, Italy, in May 2019. The 30 full papers were carefully reviewed and selected from 95 submissions. The International Conference on Algorithms and Complexity is intended to provide a forum for researchers working in all aspects of computational complexity and the use, design, analysis and experimentation of efficient algorithms and data structures. The papers present original research in the theory and applications of algorithms and computational complexity.
Algorithms For Sample Preparation With Microfluidic Lab On Chip
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Author : Bhattacharjee, Sukanta
language : en
Publisher: River Publishers
Release Date : 2019-02-05
Algorithms For Sample Preparation With Microfluidic Lab On Chip written by Bhattacharjee, Sukanta and has been published by River Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-05 with Technology & Engineering categories.
Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip