Aliphatic And Polyhalogenated Carcinogens
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Aliphatic And Polyhalogenated Carcinogens
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Author : Yin-Tak Woo
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Aliphatic And Polyhalogenated Carcinogens written by Yin-Tak Woo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIB: Aliphatic and Polyhalogenated Carcinogens covers environmentally and occupationally significant carcinogens of industrial origins. The book discusses the structure-activity relationships, metabolism, and environmental significance of the halogenated linear alkanes and alkenes and the halogenated cycloalkanes; and cycloalkene pesticides, biphenyls, and related aromatics. The text also describes the structure-activity relationships, metabolism, and environmental significance of the halogenated phenoxy acids, aromatic ethers, dibenzofurans, and dibenzo-p-dioxins; and ethylene glycol, diethylene glycol, dioxane, and related compounds. The structure-activity relationships, metabolism, and environmental significance of phenols and phenolic compounds; nitroalkanes and nitroalkenes; and acetamide, dimethylcarbamyl chloride, and related compounds thiocarbonyl compounds are also encompassed. The book further tackles the structure-activity relationships, metabolism, and environmental significance if fatty acids, detergents, and other surfactants with oncogenic potential. The text then looks into the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity. Chemists, geneticists, and those involved in cancer research will find the book invaluable.
Natural Metal Fiber And Macromolecular Carcinogens
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Author : Yin-Tak Woo
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Natural Metal Fiber And Macromolecular Carcinogens written by Yin-Tak Woo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIC: Natural, Metal, Fiber, and Macromolecular Carcinogens covers structure-carcinogenicity relationships of carcinogenic mycotoxins, carcinogenic substances generated by plants, carcinogenic metals and metalloids, and foreign-body carcinogens. The book discusses the metabolism and mechanism of carcinogenic action, physicochemical properties, other biological activities (principally mutagenicity and teratogenicity), modification of carcinogenic activity, formation and environmental significance. The text also describes the carcinogenic water-soluble high polymers and explores the intriguing problems of the carcinogenic effect of osmotic imbalance in tissue microenvironment, as well as of spontaneous malignant transformation occurring in cell cultures in vitro. Studies on tumor induction and carcinogenesis modification by nonviral nucleic acids, by nucleases, proteases, histones, and by antigenic stimulation as well as by antibodies are also considered. The book further tackles tumor-released factors as possible modifiers of carcinogenesis. The text will prove invaluable to chemists and people involved in cancer research.
Quantitative Structure Activity Relationship Qsar Models Of Mutagens And Carcinogens
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Author : Romualdo Benigni
language : en
Publisher: CRC Press
Release Date : 2003-02-26
Quantitative Structure Activity Relationship Qsar Models Of Mutagens And Carcinogens written by Romualdo Benigni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-02-26 with Medical categories.
Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides. Much has been published on the principles of QSAR in this area, but not on their application s to toxic chemicals. This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 1993
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Environmental health categories.
Oecd Series On Testing And Assessment Fundamental And Guiding Principles For Q Sar Analysis Of Chemical Carcinogens With Mechanistic Considerations
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2017-04-13
Oecd Series On Testing And Assessment Fundamental And Guiding Principles For Q Sar Analysis Of Chemical Carcinogens With Mechanistic Considerations written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-13 with categories.
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches of combining chemoinformatics and ...
Chemical Induction Of Cancer
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Author : Joseph C. Arcos
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemical Induction Of Cancer written by Joseph C. Arcos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the approach to the analysis of disease, including, of course, cancer, two major thrusts may be distinguished. These may be referred to, in shorthand, as agents and processes: the causative agents (chemical, microbial, physical, environmental, and psychosocial) and the organismic processes, initiated and furthered by the agents, culminating in observable pathology (at the macromolecular, cytological, histological, organ function, locomotor, and behavioral levels). The past 25 years, since the appearance of the first volume of the predecessor series (1) authored by the Editors of this present volume, have seen an impressive number of studies on chemicals (and other agents) as etiologic factors in the induction of cancer. The major emphasis has been on the discovery of many chemical carcinogens of widely different structures, their metabolism by various tissues and cells, and, in turn, their molecular-biochemical effects on the cells. This rapidly expanded body of information, as effectively covered in the predecessor volumes, is an excellent entree to the second half of the overall problem of chemical carcinogenesis, the processes. The active agents trigger a large array of molecular-biochemical alterations to which the target cells, target tissues, and target organisms respond in many select and common ways. This second major aspect of the induction of cancer by chemicals (and by other agents)- the sequence of cellular and tissue changes clearly relevant to cancer-remains the challenge for the future.
Toxicology And Risk Assessment
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Author : Anna M. Fan
language : en
Publisher: CRC Press
Release Date : 2015-03-04
Toxicology And Risk Assessment written by Anna M. Fan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-04 with Medical categories.
The presence of chemicals in our environment is a subject of intense interest owing to the many potential adverse health effects to humans following exposure to these chemicals. The principles and practices of risk assessment are used to assess the associated health risks to provide a scientific and health basis for guidance or regulatory standards
National Meeting
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Author : American Chemical Society. Division of Environmental Chemistry
language : en
Publisher:
Release Date : 1987-04
National Meeting written by American Chemical Society. Division of Environmental Chemistry and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-04 with Environmental chemistry categories.
Preprint Extended Abstract
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Author : American Chemical Society. Division of Environmental Chemistry
language : en
Publisher:
Release Date : 1987
Preprint Extended Abstract written by American Chemical Society. Division of Environmental Chemistry and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Environmental chemistry categories.
Journal Of Environmental Science And Health
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Author :
language : en
Publisher:
Release Date : 1983
Journal Of Environmental Science And Health written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Cancer categories.