Aluminium And Alzheimer S Disease
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Aluminium And Alzheimer S Disease
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Author : C. Exley
language : en
Publisher: Elsevier
Release Date : 2001-07-03
Aluminium And Alzheimer S Disease written by C. Exley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-03 with Science categories.
The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to impact upon mammalian physiology and function and range from clinical studies, through animal models of disease to the detailed biochemistry of aluminium toxicity. Chapters are also included on epidemiology and other factors involved in the aetiology of Alzheimer's. This is the first time that this subject has been treated in such a comprehensive manner. The research detailed in each chapter, includes the latest research in the field, it has been critically appraised and this appraisal has been used by each author to present an informed opinion of its relevance to aluminium and Alzheimer's disease. The chapters are much more than reviews; they are a statement of the state of the art and of what the future may hold for research in this field. As a whole they show the high quality of research that has been carried out in our efforts to understand the toxicity of aluminium in man and that we are far away from discounting the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease.
Aluminium In Biology And Medicine
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Aluminium In Biology And Medicine written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Medical categories.
Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examines the chemistry and biology of aluminum compounds focusing on the evidence for and against aluminum's role in Alzheimer's disease.
Aluminum Drinking Water And Alzheimer S Disease
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Author : Steve Harold Reiber
language : en
Publisher:
Release Date : 1996
Aluminum Drinking Water And Alzheimer S Disease written by Steve Harold Reiber and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Aluminum categories.
Aluminium And Alzheimer S Disease
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Author : W. F. Forbes
language : en
Publisher:
Release Date : 1995
Aluminium And Alzheimer S Disease written by W. F. Forbes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
Neurotoxicity Of Aluminum
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Author : Qiao Niu
language : en
Publisher: Springer Nature
Release Date : 2023-07-08
Neurotoxicity Of Aluminum written by Qiao Niu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-08 with Medical categories.
This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
Biochemical Mechanisms Of Aluminium Induced Neurological Disorders
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Author : Touqeer Ahmed
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-12-13
Biochemical Mechanisms Of Aluminium Induced Neurological Disorders written by Touqeer Ahmed and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with Science categories.
Aluminium is a chemical element present in earth’s crust and it is a known environmental toxin which has been found to be associated with various neurological disorders. Aluminium has been found to be a very strong risk factor for the development of Alzheimer’s disease. Biochemical Mechanisms of Aluminium Induced Neurological Disorders explains the association of aluminium with neurological disorders. The book introduces the reader to sources of aluminium exposure, followed by an explanation of pharmacokinetics of aluminium and the different biochemical pathways that cause neurological effects. Chapters cover the typical mechanisms associated with aluminium neurotoxicity such as synaptic impairment as well as recent topics of interest such as the role of aluminum in impairing blood-brain barrier functions. Separate chapters which cover clinical evidence of aluminium toxicity and its management are also included in the book. Biochemical Mechanisms of Aluminium Induced Neurological Disorders is a concise, yet informative reference on the subject of aluminium neurotoxicity for all readers, whether they are students of biochemistry, pharmacology and toxicology, clinical neurologists, environmentalists interested in metal pollution or general readers who want to learn about the toxic effects of aluminium in humans.
Aluminum Neurotoxicity
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Author : Leopold Liss
language : en
Publisher:
Release Date : 1980
Aluminum Neurotoxicity written by Leopold Liss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Aluminum categories.
Alzheimer S Disease Cellular And Molecular Aspects Of Amyloid Beta
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Author : J. Robin Harris
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-11-22
Alzheimer S Disease Cellular And Molecular Aspects Of Amyloid Beta written by J. Robin Harris and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Science categories.
To understand Alzheimer's disease (AD) is one of the major thrusts of present-day clinical research, strongly supported by more fimdamental cellular, biochemical, immunological and structural studies. It is these latter that receive attention within this book. This compilation of 20 chapters indicates the diversity of work currently in progress and summarizes the current state of knowledge. Experienced authors who are scientifically active in their fields of study have been selected as contributors to this book, in an attempt to present a reasonably complete survey of the field. Inevitably, some exciting topics for one reason or another have not been included, for which we can only apologize. Standardization of terminology is often a problem in science, not least in the Alzheimer field; editorial effort has been made to achieve standardization between the Chapters, but some minor yet acceptable personal / author variation is still present, i. e. P-amyloid/amyloid-P; Ap42/Apl-42/APi. 42! The book commences with a broad survey of the contribution that the range of available microscopical techniques has made to the study of Alzheimer's amyloid plaques and amyloid fibrillogenesis. This chapter also serves as an Introduction to the book, since several of the topics introduced here are expanded upon in later chapters. Also, it is significant to the presence of this chapter that the initial discovery of brain plaques, by Alois Alzheimer, utilized light microscopy, a technique that continues to be extremely valuable in present-day AD research.
Aluminum And Health
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Author : H. J. Gitelman
language : en
Publisher: CRC Press
Release Date : 1988-11-04
Aluminum And Health written by H. J. Gitelman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-11-04 with Technology & Engineering categories.
A hot topic. Contributors address: guidelines for sampling and analyzing aluminum levels in the body, how acid rain alters aluminum in the typical North American diet, the alleged link between aluminum and Alzheimer's disease, the role of aluminum in the dynamics of bone physiology, occupational exp
Toxic Metal Syndrome
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Author : Herman Richard Casdorph
language : en
Publisher: Penguin
Release Date : 1995
Toxic Metal Syndrome written by Herman Richard Casdorph and has been published by Penguin this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Fiction categories.
"Toxic Metal Syndrome" exposes the root causes of the wastes that cause debilitating conditions and pollute the environment and explodes the myth that nothing can be done to avoid or treat them.