Alzheimer S Disease Lessons From Cell Biology
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Alzheimer S Disease Lessons From Cell Biology
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Author : Ken S. Kosik
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Alzheimer S Disease Lessons From Cell Biology written by Ken S. Kosik and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Like the unflinching gaze of Captain Ahab walking the deck of the Pequod, Alzheimer researchers have had their sights fixed firmly on the disease for many years. Now, as this volume amply demonstrates, accomplished researchers from other fields, who have thought deeply about cell biological problems are applying their insights to Alzheimer's disease. The contri butions here represent the text versions of the proceedings from the tenth "Colloque medecine et recherche" of the Fondation IPSEN devoted to research on Alzheimer's disease. The symposium, entitled "Alzheimer's Disease: Lessons from Cell Biology" was held in Paris on April 25, 1994. As is apparent from the varied backgrounds of the contributors, the scientific pursuit of Alzheimer's disease has begun to meld with more basic disciplines, particularly cell biology. While on the one hand, new areas of specialization are continuously emerging, the boundaries of older disciplines are increas ingly blurred. Perhaps for most of the years since the first descriptions of the disease in 1907, the science of Alzheimer's disease was descriptive, and lay in the province of pathologists. This time period, during which a great deal was learned about the topography of senile plaques and neurofibrillary tangles, culminated with an ultrastructural description of these hallmark structures. The modern era of Alzheimer's disease research opened with the iden tification of the component proteins in plaques and tangles.
Alzheimer S Disease
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Author : K. S. Kosik
language : en
Publisher:
Release Date : 1995
Alzheimer S Disease written by K. S. Kosik and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
Alzheimer S Disease Lessons From Cell Biology
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Author :
language : en
Publisher:
Release Date : 1995
Alzheimer S Disease Lessons From Cell Biology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
Insights Into Human Neurodegeneration Lessons Learnt From Drosophila
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Author : Mousumi Mutsuddi
language : en
Publisher: Springer Nature
Release Date : 2019-12-05
Insights Into Human Neurodegeneration Lessons Learnt From Drosophila written by Mousumi Mutsuddi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-05 with Medical categories.
This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.
Cell Biology Of Alzheimer S Disease
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Author : Syed Ather Enam
language : en
Publisher:
Release Date : 1991
Cell Biology Of Alzheimer S Disease written by Syed Ather Enam and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with categories.
Genes Environment And Alzheimer S Disease
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Author : Orly Lazarov
language : en
Publisher: Academic Press
Release Date : 2016-02-25
Genes Environment And Alzheimer S Disease written by Orly Lazarov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-25 with Psychology categories.
Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. Provides the first volume to link genetic and environmental risk factors for Alzheimer’s disease and dementia Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer’s disease and cognitive decline Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists
The Changing Brain
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Author : Ira B. Black
language : en
Publisher: Oxford University Press, USA
Release Date : 2002
The Changing Brain written by Ira B. Black and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
It features extensive listings of Web sites for community organization practice and is dedicated to the idea that the community organizer, to be truly effective, must be prepared to be an active learner."--BOOK JACKET.
Biochemistry And Cell Biology Of Ageing Part Iv Clinical Science
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Author : J. Robin Harris
language : en
Publisher: Springer Nature
Release Date : 2023-04-29
Biochemistry And Cell Biology Of Ageing Part Iv Clinical Science written by J. Robin Harris and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-29 with Family & Relationships categories.
This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice. To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute to ageing events and how various organs and tissues (e.g. tendons, ears, heart muscle, and the endocrine system) age. This book follows on from Parts I, II and III of Biochemistry and Cell Biology of Ageing within the Subcellular Biochemistry book series and aims to bring the subcellular and clinical areas into closer contact by including interesting and significant biomedical ageing topics that were not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Modification Of Cell To Cell Signals During Normal And Pathological Aging
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Author : Stefano Govoni
language : en
Publisher: Springer
Release Date : 1987
Modification Of Cell To Cell Signals During Normal And Pathological Aging written by Stefano Govoni and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Aging categories.
Alzheimer S Disease
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Author : Sangram S. Sisodia
language : en
Publisher: Springer
Release Date : 2010-10-29
Alzheimer S Disease written by Sangram S. Sisodia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-29 with Medical categories.
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.