Aminopeptidases In Biology And Disease
DOWNLOAD
Download Aminopeptidases In Biology And Disease PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Aminopeptidases In Biology And Disease book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Aminopeptidases In Biology And Disease
DOWNLOAD
Author : Nigel M. Hooper
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Aminopeptidases In Biology And Disease written by Nigel M. Hooper and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Aminopeptidases in Biology and Disease provides a comprehensive review of the emerging role of aminopeptidases in a range of biological processes and disease situations. Processes as diverse as angiogenesis, antigen presentation, neuropeptide and hormone processing, pregnancy and reproduction, protein turnover, memory, inflammation, tumour growth, cancer and metastasis, blood pressure and hypertension all critically involve one or more aminopeptidases. The individual chapters have been written by experts in the field who have provided detailed accounts of the central roles played by various aminopeptidases in biology and disease.
Dipeptidyl Aminopeptidases
DOWNLOAD
Author : Uwe Lendeckel
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-12-11
Dipeptidyl Aminopeptidases written by Uwe Lendeckel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-11 with Medical categories.
This is the first comprehensive volume on Dipeptidyl Aminopeptidases that can be marketed to a wide variety of disciplines, as well as to a variety of clinicians. Leading experts in the field contribute to this state-of-the-art view on these enzymes. This book comes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent.
Ectopeptidases
DOWNLOAD
Author : Jürgen Langner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Ectopeptidases written by Jürgen Langner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The idea to compile recent results on the ectoenzymes aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 arose from the great interest given by readers world-wide to the two proceedings volumes edited by us in 1997 and 2000 (Ansorge and Langner, 1997; Langner and Ansorge, 2000). These volumes contained the presentations at two symposia held in Magdeburg (Germany) in 1996 and 1999 under the title "Cellular peptidases in immune functions and diseases", which was also the name of the Sonderforschungsbereich in Magdeburg, sponsored by the Deutsche Forschungsgemeinschaft between 1995 and 2001. Our groups in Magdeburg and Halle during the last two decades have provided results on these two enzymes in cells of the hematopoietic system that justify a review in an edited monograph like the present one (see the reviews by Kahne et at. , 1999; Lendeckel et at. ,1999; Riemann et at. , 1999). There are, however, many other groups in Europe, US and Japan which made important contributions to this field and particularly in topics improving the understanding of physiological and pathophysiological roles ofAPN/CD13 and DPIV/CD26. Therefore we decided to invite some of them to contribute reviews of their results to this book. Having worked for about 40 years in the field of proteolysis, for both of us to see the development of activities and knowledge from protein chemistry and enzymology to physiology and pathophysiology and even to therapy is very stimulating and fascinating. Of course, this development also reflects the dramatic improvement and refinement of methods.
Dipeptidyl Aminopeptidases In Health And Disease
DOWNLOAD
Author : Martin Hildebrandt
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Dipeptidyl Aminopeptidases In Health And Disease written by Martin Hildebrandt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: - Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.
Cell Surface Peptidases In Health And Disease
DOWNLOAD
Author : A.J. Kenny
language : en
Publisher: Taylor & Francis
Release Date : 1997-07
Cell Surface Peptidases In Health And Disease written by A.J. Kenny and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-07 with Medical categories.
Cells bristle with a battery of surface enzymes, of which the peptidases form the largest and best studied group. These ectopeptidases play crucial roles in many diverse biological functions, including the termination of peptide signals in the nervous system and at peripheral sites. Some of their key physiological roles, such as those of angiotensin- and endothelin-converting enzymes in generating vasoconstrictive agents and endopeptidase-24.11 in activating natriuretic peptides, enkephalins and tachykinins, have made them prime targets for the pharmaceutical industry. Interest among immunologists and haematologists was aroused when several were shown to be identical to cell-surface markers (CD antigens) on human leukocytes. Virologists have been excited to find that some double as receptors for certain viruses.
Aminopeptidases
DOWNLOAD
Author : Allen Taylor
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Aminopeptidases written by Allen Taylor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
This book summarizes recently gathered information regarding the aminopeptidases. Nomenclature, distributions in the plant and animal kingdoms, structural and compositional information, mechanistic studies, homologies, physiological, medical and industrial uses, and molecular genetics of aminopeptidases are described.
Cellular Peptidases In Immune Functions And Diseases 2
DOWNLOAD
Author : Jürgen Langner
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Cellular Peptidases In Immune Functions And Diseases 2 written by Jürgen Langner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.
Handbook Of Proteolytic Enzymes
DOWNLOAD
Author : Alan J. Barrett
language : en
Publisher: Academic Press
Release Date : 2012-10-30
Handbook Of Proteolytic Enzymes written by Alan J. Barrett and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-30 with Science categories.
Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. The only comprehensive book on proteolytic enzymes Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features Over 1000 peptidases included
Long Lived Proteins In Human Aging And Disease
DOWNLOAD
Author : Roger J. W. Truscott
language : en
Publisher: John Wiley & Sons
Release Date : 2021-04-19
Long Lived Proteins In Human Aging And Disease written by Roger J. W. Truscott and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-19 with Science categories.
This authoritative overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins. It describes the molecular mechanisms of aging on the protein level, in particular the most common side chain modifications and includes analytical methods to study protein half-life and the accumulation of modifications. Finally, the impact of protein aging on several age-related disases in humans is dissected, and their role in limiting human lifespan is discussed.
Mast Cell Biology
DOWNLOAD
Author : Alasdair M. Gilfillan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Mast Cell Biology written by Alasdair M. Gilfillan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.