An Approach To Model Validation And Model Based Prediction
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An Approach To Model Validation And Model Based Prediction
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Author : Brian Milne Rutherford
language : en
Publisher:
Release Date : 2003
An Approach To Model Validation And Model Based Prediction written by Brian Milne Rutherford and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Mathematical models categories.
Clinical Prediction Models
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Author : Ewout W. Steyerberg
language : en
Publisher: Springer
Release Date : 2019-07-22
Clinical Prediction Models written by Ewout W. Steyerberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-22 with Medical categories.
The second edition of this volume provides insight and practical illustrations on how modern statistical concepts and regression methods can be applied in medical prediction problems, including diagnostic and prognostic outcomes. Many advances have been made in statistical approaches towards outcome prediction, but a sensible strategy is needed for model development, validation, and updating, such that prediction models can better support medical practice. There is an increasing need for personalized evidence-based medicine that uses an individualized approach to medical decision-making. In this Big Data era, there is expanded access to large volumes of routinely collected data and an increased number of applications for prediction models, such as targeted early detection of disease and individualized approaches to diagnostic testing and treatment. Clinical Prediction Models presents a practical checklist that needs to be considered for development of avalid prediction model. Steps include preliminary considerations such as dealing with missing values; coding of predictors; selection of main effects and interactions for a multivariable model; estimation of model parameters with shrinkage methods and incorporation of external data; evaluation of performance and usefulness; internal validation; and presentation formatting. The text also addresses common issues that make prediction models suboptimal, such as small sample sizes, exaggerated claims, and poor generalizability. The text is primarily intended for clinical epidemiologists and biostatisticians. Including many case studies and publicly available R code and data sets, the book is also appropriate as a textbook for a graduate course on predictive modeling in diagnosis and prognosis. While practical in nature, the book also provides a philosophical perspective on data analysis in medicine that goes beyond predictive modeling. Updates to this new and expanded edition include: • A discussion of Big Data and its implications for the design of prediction models • Machine learning issues • More simulations with missing ‘y’ values • Extended discussion on between-cohort heterogeneity • Description of ShinyApp • Updated LASSO illustration • New case studies
Approach And Verification
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Author : Subramaniam Ganesan
language : en
Publisher: SAE International
Release Date : 2010-11-29
Approach And Verification written by Subramaniam Ganesan and has been published by SAE International this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-29 with Technology & Engineering categories.
Automotive systems engineering addresses the system throughout its life cycle, including requirement, specification, design, implementation, verification and validation of systems, modeling, simulation, testing, manufacturing, operation and maintenance. This book is the fourth in a series of four volumes on this subject and features 12 papers, published between 2002-2009, that address the challenges and importance of systems approach in system verification and validation, stressing the use of advanced tools and approaches. Topics covered include: Systems integration and verification Software engineering in future automotive systems development Configuration management of the model-based design process
Multivariate Statistical Machine Learning Methods For Genomic Prediction
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Author : Osval Antonio Montesinos López
language : en
Publisher: Springer Nature
Release Date : 2022-02-14
Multivariate Statistical Machine Learning Methods For Genomic Prediction written by Osval Antonio Montesinos López and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-14 with Technology & Engineering categories.
This book is open access under a CC BY 4.0 license This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.
Python Data Science Handbook
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Author : Jake VanderPlas
language : en
Publisher: "O'Reilly Media, Inc."
Release Date : 2016-11-21
Python Data Science Handbook written by Jake VanderPlas and has been published by "O'Reilly Media, Inc." this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-21 with Computers categories.
For many researchers, Python is a first-class tool mainly because of its libraries for storing, manipulating, and gaining insight from data. Several resources exist for individual pieces of this data science stack, but only with the Python Data Science Handbook do you get them all—IPython, NumPy, Pandas, Matplotlib, Scikit-Learn, and other related tools. Working scientists and data crunchers familiar with reading and writing Python code will find this comprehensive desk reference ideal for tackling day-to-day issues: manipulating, transforming, and cleaning data; visualizing different types of data; and using data to build statistical or machine learning models. Quite simply, this is the must-have reference for scientific computing in Python. With this handbook, you’ll learn how to use: IPython and Jupyter: provide computational environments for data scientists using Python NumPy: includes the ndarray for efficient storage and manipulation of dense data arrays in Python Pandas: features the DataFrame for efficient storage and manipulation of labeled/columnar data in Python Matplotlib: includes capabilities for a flexible range of data visualizations in Python Scikit-Learn: for efficient and clean Python implementations of the most important and established machine learning algorithms
Robust Control
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Author : Shankar P. Bhattacharyya
language : en
Publisher: Prentice Hall
Release Date : 1995
Robust Control written by Shankar P. Bhattacharyya and has been published by Prentice Hall this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Technology & Engineering categories.
Crucial in the analysis and design of control systems, this book presents a unified approach to robust stability theory, including both linear and nonlinear systems, and provides a self-contained and complete account of the available results in the field of robust control under parametric uncertainty.
Configurable Software Performance Completions Through Higher Order Model Transformations
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Author : Happe, Lucia
language : en
Publisher: KIT Scientific Publishing
Release Date : 2014-11-26
Configurable Software Performance Completions Through Higher Order Model Transformations written by Happe, Lucia and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-26 with Electronic computers. Computer science categories.
Chillies is a novel approach for variable model transformations closing the gap between abstract architecture models, used for performance prediction, and required low-level details. We enable variability of transformations using chain of generators based on the Higher-Order Transformation (HOT). HOTs target different goals, such as template instantiation or transformation composition. In addition, we discuss state-dependent behavior in prediction models and quality of model transformations.
An Approach To Model Validation And Model Based Prediction Polyurethane Foam Case Study
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Author : Kevin J. Dowding
language : en
Publisher:
Release Date : 2003
An Approach To Model Validation And Model Based Prediction Polyurethane Foam Case Study written by Kevin J. Dowding and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Enhanced software methodology and improved computing hardware have advanced the state of simulation technology to a point where large physics-based codes can be a major contributor in many systems analyses. This shift toward the use of computational methods has brought with it new research challenges in a number of areas including characterization of uncertainty, model validation, and the analysis of computer output. It is these challenges that have motivated the work described in this report. Approaches to and methods for model validation and (model-based) prediction have been developed recently in the engineering, mathematics and statistical literatures. In this report we have provided a fairly detailed account of one approach to model validation and prediction applied to an analysis investigating thermal decomposition of polyurethane foam. A model simulates the evolution of the foam in a high temperature environment as it transforms from a solid to a gas phase. The available modeling and experimental results serve as data for a case study focusing our model validation and prediction developmental efforts on this specific thermal application. We discuss several elements of the ''philosophy'' behind the validation and prediction approach: (1) We view the validation process as an activity applying to the use of a specific computational model for a specific application. We do acknowledge, however, that an important part of the overall development of a computational simulation initiative is the feedback provided to model developers and analysts associated with the application. (2) We utilize information obtained for the calibration of model parameters to estimate the parameters and quantify uncertainty in the estimates. We rely, however, on validation data (or data from similar analyses) to measure the variability that contributes to the uncertainty in predictions for specific systems or units (unit-to-unit variability). (3) We perform statistical analyses and hypothesis tests as a part of the validation step to provide feedback to analysts and modelers. Decisions on how to proceed in making model-based predictions are made based on these analyses together with the application requirements. Updating modifying and understanding the boundaries associated with the model are also assisted through this feedback. (4) We include a ''model supplement term'' when model problems are indicated. This term provides a (bias) correction to the model so that it will better match the experimental results and more accurately account for uncertainty. Presumably, as the models continue to develop and are used for future applications, the causes for these apparent biases will be identified and the need for this supplementary modeling will diminish. (5) We use a response-modeling approach for our predictions that allows for general types of prediction and for assessment of prediction uncertainty. This approach is demonstrated through a case study supporting the assessment of a weapons response when subjected to a hydrocarbon fuel fire. The foam decomposition model provides an important element of the response of a weapon system in this abnormal thermal environment. Rigid foam is used to encapsulate critical components in the weapon system providing the needed mechanical support as well as thermal isolation. Because the foam begins to decompose at temperatures above 250 C, modeling the decomposition is critical to assessing a weapons response. In the validation analysis it is indicated that the model tends to ''exaggerate'' the effect of temperature changes when compared to the experimental results. The data, however, are too few and to restricted in terms of experimental design to make confident statements regarding modeling problems. For illustration, we assume these indications are correct and compensate for this apparent bias by constructing a model supplement term for use in the model-based predictions. Several hypothetical prediction problems are created and addressed. Hypothetical problems are used because no guidance was provided concerning what was needed for this aspect of the analysis. The resulting predictions and corresponding uncertainty assessment demonstrate the flexibility of this approach.
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 2003-07
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07 with Environmental health categories.
Automated Improvement Of Software Architecture Models For Performance And Other Quality Attributes
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Author : Koziolek, Anne
language : en
Publisher: KIT Scientific Publishing
Release Date : 2014-01-07
Automated Improvement Of Software Architecture Models For Performance And Other Quality Attributes written by Koziolek, Anne and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-07 with Computers categories.
Quality attributes, such as performance or reliability, are crucial for the success of a software system and largely influenced by the software architecture. Their quantitative prediction supports systematic, goal-oriented software design and forms a base of an engineering approach to software design. This thesis proposes a method and tool to automatically improve component-based software architecture (CBA) models based on such quantitative quality prediction techniques.