An Investigation Of Microrna Target Regulation Mechanisms Using An Integrative Approach
DOWNLOAD
Download An Investigation Of Microrna Target Regulation Mechanisms Using An Integrative Approach PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get An Investigation Of Microrna Target Regulation Mechanisms Using An Integrative Approach book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
An Investigation Of Microrna Target Regulation Mechanisms Using An Integrative Approach
DOWNLOAD
Author : Ulf Schmitz
language : en
Publisher: Logos Verlag Berlin GmbH
Release Date : 2015-06-29
An Investigation Of Microrna Target Regulation Mechanisms Using An Integrative Approach written by Ulf Schmitz and has been published by Logos Verlag Berlin GmbH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-29 with Computers categories.
This work is a showcase for the integration of systems biology and bioinformatics tools, algorithms and models for deciphering biological phenomena. More specifically, it integrates (i) prediction algorithms for identifying and characterizing molecular interactions, (ii) structural modelling of molecule complexes, (iii) network analysis approaches, and (iv) mathematical modelling and simulation. Two comprehensive workflows are implemented for the analysis of collective target gene regulation by microRNAs and for the prediction of cooperating microRNA pairs and their mutual target genes. In two case studies mechanisms of fine-tuned target gene regulation are revealed for different cellular processes and the phenomenon of cooperative target regulation is identified as frequent mechanism of gene regulation in humans.
Integrated Uncertainty In Knowledge Modelling And Decision Making
DOWNLOAD
Author : Zengchang Qin
language : en
Publisher: Springer
Release Date : 2013-06-20
Integrated Uncertainty In Knowledge Modelling And Decision Making written by Zengchang Qin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-20 with Computers categories.
This book constitutes the refereed proceedings of the International Symposium on Integrated Uncertainty in Knowledge Modeling and Decision Making, IUKM 2013, held in Beijing China, in July 2013. The 19 revised full papers were carefully reviewed and selected from 49 submissions and are presented together with keynote and invited talks. The papers provide a wealth of new ideas and report both theoretical and applied research on integrated uncertainty modeling and management.
Perspectives In Genetic And Epigenetic Regulatory Mechanisms In Dental And Craniofacial Biology
DOWNLOAD
Author : Weimin Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-29
Perspectives In Genetic And Epigenetic Regulatory Mechanisms In Dental And Craniofacial Biology written by Weimin Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-29 with Science categories.
Genetic factors have been proved to be involved in almost all dental and craniomaxillofacial diseases. Typical dental and craniomaxillofacial hereditary diseases refer to hereditary diseases which occurs in the oral and maxillofacial area, as well as systemic or other system hereditary diseases accompanied by oral abnormality. The former includes enamel hypoplasia, dentin hypoplasia and cleft lip and palate, which mainly occur in the oral cavity. While the latter commonly includes cranial clavicle hypoplasia, congenital ectodermal hypoplasia, osteogenesis imperfecta, and osteosclerosis. In addition, common diseases that appear locally in the oral cavity, including caries, periodontitis, oral mucosal diseases and head and neck tumors, are also considered to be related to genetic variations. With the increase of large-scale genome-wide association analysis study (GWAS) during the last decade, common loci for many genetic diseases have been identified. To date, most evidence comes from GWAS of dental caries and periodontal disease, which have tested associations between millions of single nucleotide polymorphisms (SNPs) and typical binary phenotypes. However, genetic loci for other rare oral diseases remain to be studied due to their large variety and low incidence. Multi-omics sequencing technology provides a more powerful tool for identifying the pathogenic genes of dental and craniomaxillofacial hereditary diseases at genomic, transcriptomic and proteomic level. In addition, with the development of single-cell multi-omics technology, specific cell populations involved in the pathogenesis of dental and craniomaxillofacial hereditary disease can be more accurately identified at single-cell resolution.
Machine Learning Methodologies To Study Molecular Interactions
DOWNLOAD
Author : Elif Ozkirimli
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-21
Machine Learning Methodologies To Study Molecular Interactions written by Elif Ozkirimli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-21 with Science categories.
Dr. Elif Ozkirimli is a full time employee of F. Hoffmann-La Roche AG, Switzerland and Dr. Artur Yakimovich is a full time employee of Roche Products Limited, UK. All other Topic Editors declare no competing interests with regards to the Research Topic.
Impact Of Climate Change On Medicinal And Herbal Plant Microrna
DOWNLOAD
Author : Kanchanlata Tungare
language : en
Publisher: CRC Press
Release Date : 2025-09-30
Impact Of Climate Change On Medicinal And Herbal Plant Microrna written by Kanchanlata Tungare and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-09-30 with Science categories.
Climate change poses unprecedented challenges to plant growth, biodiversity, and productivity, necessitating innovative strategies for sustainability. Impact of Climate Change on Medicinal and Herbal Plant microRNA delves into the intricate relationship between climate‐induced stress and the molecular mechanisms underpinning plant adaptation, with a special focus on microRNAs (miRNAs). This book provides an in‐depth exploration of miRNAs as pivotal regulators in plant biology, offering insights into their biogenesis, functional roles, and applications in stress management and crop improvement. Highlighting the interdisciplinary approach to understanding plant resilience, this book examines critical topics, including the impact of abiotic stressors like heavy metals and elevated CO2 levels, regulatory roles of miRNAs in photosynthesis and productivity, and the integration of bioinformatics and epigenetics in miRNA research. Through comprehensive chapters, readers gain knowledge about miRNA‐mediated bioengineering, genome stability, and the emerging potential of omics technologies to combat the effects of climate change on agriculture. Key Features: A thorough analysis of miRNA biogenesis, regulation, and degradation, along with their myriad functional roles in plant biology Exploration of abiotic stress tolerance mechanisms in medicinal, cereal, legume, tuber, fruit, biofuel, and beverage crops Insights into bioinformatics tools and databases for miRNA analysis and their implications for stress tolerance studies Discussions on miRNA‐mediated bioengineering for climate‐resilient crops and recent advances in omics approaches Designed for researchers, students, and professionals in plant sciences, bioinformatics, and climate studies, this book bridges fundamental and applied research, making it an essential resource for addressing climate variability through molecular innovations.
Genomics Proteomics And Metabolomics In Nutraceuticals And Functional Foods
DOWNLOAD
Author : Debasis Bagchi
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-18
Genomics Proteomics And Metabolomics In Nutraceuticals And Functional Foods written by Debasis Bagchi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-18 with Technology & Engineering categories.
Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutriethics and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals.
Prediction And Explanation In Biomedicine Using Network Based Approaches
DOWNLOAD
Author : Alessio Martino
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-12
Prediction And Explanation In Biomedicine Using Network Based Approaches written by Alessio Martino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-12 with Medical categories.
Microrna Cancer Regulation
DOWNLOAD
Author : Ulf Schmitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-03
Microrna Cancer Regulation written by Ulf Schmitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-03 with Medical categories.
This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.
The Development And Application Of Multi Omics Integration Approaches To Dissecting Complex Traits In Plants
DOWNLOAD
Author : Shang-Qian Xie
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-06
The Development And Application Of Multi Omics Integration Approaches To Dissecting Complex Traits In Plants written by Shang-Qian Xie and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-06 with Science categories.
Novel Roles Of Non Coding Brain Rnas In Health And Disease
DOWNLOAD
Author : Hermona Soreq
language : en
Publisher: Frontiers E-books
Release Date : 2014-10-23
Novel Roles Of Non Coding Brain Rnas In Health And Disease written by Hermona Soreq and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-23 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Non-coding RNAs (ncRNAs), and in particular microRNAs are rapidly becoming the focus of research interest in numerous basic and translational fields, including brain research; and their importance for many aspects in brain functioning merits special discussion. The wide-scope, multi-targeted and highly efficient manner of ncRNA regulatory activities draws attention to this topic by many, but the available research and analysis tools and experimental protocols are still at their infancy, and calls for special discussion given their importance for many aspects in brain functioning. This eBook is correspondingly focused on the search for, identification and exploration of those non-coding RNAs whose activities modulate the multi-leveled functions of the eukaryotic brain. The different articles strive to cover novel approaches for identifying and establishing ncRNA-target relationships, provide state of the art reports of the affected neurotransmission pathways, describe inherited and acquired changes in ncRNA functioning and cover the use of ncRNA mimics and blockade tools for interference with their functions in health and disease of the brain. Non-coding RNAs are here to stay, and this exciting eBook provides a glimpse into their impact on our brain’s functioning at the physiology, cell biology, behavior and immune levels.