Analysis Of Biological Systems
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Analysis Of Biological Systems
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Author : Corrado Priami
language : en
Publisher: World Scientific
Release Date : 2015-01-29
Analysis Of Biological Systems written by Corrado Priami and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-29 with Science categories.
Modeling is fast becoming fundamental to understanding the processes that define biological systems. High-throughput technologies are producing increasing quantities of data that require an ever-expanding toolset for their effective analysis and interpretation. Analysis of high-throughput data in the context of a molecular interaction network is particularly informative as it has the potential to reveal the most relevant network modules with respect to a phenotype or biological process of interest. Analysis of Biological Systems collects classical material on analysis, modeling and simulation, thereby acting as a unique point of reference. The joint application of statistical techniques to extract knowledge from big data and map it into mechanistic models is a current challenge of the field, and the reader will learn how to build and use models even if they have no computing or math background. An in-depth analysis of the currently available technologies, and a comparison between them, is also included. Unlike other reference books, this in-depth analysis is extended even to the field of language-based modeling. The overall result is an indispensable, self-contained and systematic approach to a rapidly expanding field of science. Contents:Algorithmic Systems BiologySetting the ContextSystems and ModelsStatic Modeling TechnologiesDynamic Modeling TechnologiesLanguage-based ModelingDynamic Modeling ProcessSimulationPerspectives and ConclusionsAppendix A: Basic MathAppendix B: Probability and StatisticsAppendix C: Semantics of Modeling Languages Readership: Graduate students in computer science, physics, mathematics or engineering or biology-related fields who want to better understand how to develop and use models of biological systems. Practitioners in systems biology who want to understand algorithmic modeling and algorithmic systems biology. Key Features:The book jointly deals with static (statistical) and dynamic (simulation) technologies making it a strong reference for who wants to approach real systems biology problemsThe content of the book is the result of more than ten years application of the material in university courses and to industrial-level problems in systems pharmacology and systems nutritionThere is no reference work available for the field of language-based modeling that is studied in depth in this bookKeywords:Modeling;Simulation;Network Analysis;Systems Biology;Systems Nutrition;Systems Pharmacology;Stochastic Models;Programming Biology;Multivariate Analysis
Symbolic Approaches To Modeling And Analysis Of Biological Systems
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Author : Cedric Lhoussaine
language : en
Publisher: John Wiley & Sons
Release Date : 2023-08-29
Symbolic Approaches To Modeling And Analysis Of Biological Systems written by Cedric Lhoussaine and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-29 with Computers categories.
Continuum Analysis Of Biological Systems
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Author : G.K. Suraishkumar
language : en
Publisher: Springer
Release Date : 2014-07-08
Continuum Analysis Of Biological Systems written by G.K. Suraishkumar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Technology & Engineering categories.
This book addresses the analysis, in the continuum regime, of biological systems at various scales, from the cellular level to the industrial one. It presents both fundamental conservation principles (mass, charge, momentum and energy) and relevant fluxes resulting from appropriate driving forces, which are important for the analysis, design and operation of biological systems. It includes the concept of charge conservation, an important principle for biological systems that is not explicitly covered in any other book of this kind. The book is organized in five parts: mass conservation; charge conservation; momentum conservation; energy conservation and multiple conservations simultaneously applied. All mathematical aspects are presented step by step, allowing any reader with a basic mathematical background (calculus, differential equations, linear algebra, etc.) to follow the text with ease. The book promotes an intuitive understanding of all the relevant principles and in so doing facilitates their application to practical issues related to design and operation of biological systems. Intended as a self-contained textbook for students in biotechnology and in industrial, chemical and biomedical engineering, this book will also represent a useful reference guide for professionals working in the above-mentioned fields.
Methods In Bioengineering
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Author : Arul Jayaraman
language : en
Publisher: Artech House
Release Date : 2009
Methods In Bioengineering written by Arul Jayaraman and has been published by Artech House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.
"This cutting-edge volume provides a detailed look at the two main aspects of systems biology: the design of sophisticated experimental methods and the development of complex models to analyze the data. Focusing on methods that are being used to solve current problems in biomedical science and engineering, this comprehensive, richly illustrated resource shows you how to: design of state-of-the art methods for analyzing biological systems Implement experimental approaches for investigating cellular behavior in health and disease; use algorithms and modeling techniques for quantitatively describing biomedical problems; and integrate experimental and computational approaches for a more complete view of biological systems." --Book Jacket.
The Dynamics Of Biological Systems
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Author : Arianna Bianchi
language : en
Publisher: Springer Nature
Release Date : 2019-10-02
The Dynamics Of Biological Systems written by Arianna Bianchi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-02 with Mathematics categories.
The book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Séminaire de Mathématiques Supérieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight - discuss innovative methods for the analysis of biological processes, - contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.
Complexity Analysis And Control Of Singular Biological Systems
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Author : Qingling Zhang
language : en
Publisher: Springer
Release Date : 2012-02-16
Complexity Analysis And Control Of Singular Biological Systems written by Qingling Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-16 with Technology & Engineering categories.
Complexity, Analysis and Control of Singular Biological Systems follows the control of real-world biological systems at both ecological and phyisological levels concentrating on the application of now-extensively-investigated singular system theory. Much effort has recently been dedicated to the modelling and analysis of developing bioeconomic systems and the text establishes singular examples of these, showing how proper control can help to maintain sustainable economic development of biological resources. The book begins from the essentials of singular systems theory and bifurcations before tackling the use of various forms of control in singular biological systems using examples including predator-prey relationships and viral vaccination and quarantine control. Researchers and graduate students studying the control of complex biological systems are shown how a variety of methods can be brought to bear and practitioners working with the economics of biological systems and their control will also find the monograph illuminating.
Elemental Analysis Of Biological Systems
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Author : G. Venkatesh Iyengar
language : en
Publisher: CRC Press
Release Date : 1989-05-31
Elemental Analysis Of Biological Systems written by G. Venkatesh Iyengar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-05-31 with Medical categories.
The purpose of this volume is to emphasize the fact that biological trace element research is a multidisciplinary science which requires a prudent combination of biological insight and analytical awareness. The text frequently stresses that accurate measurements on biologically and analytically "valid" samples hold the key for success in future investigations. It reminds the analytical scientists and the life sciences researchers that their perceptions should extend beyond conventional limits - namely, the former as generators of data and the latter as interpreters of those findings. This book enables the reader to understand the intricacies of elemental composition studies in biological systems, and also provides a valuable source of information to biologists, biochemists, physicians, nutritionists and related scientific workers who intend to draw meaningful conclusions from the analytical findings.
Thermodynamic Network Analysis Of Biological Systems
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Author : J. Schnakenberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Thermodynamic Network Analysis Of Biological Systems written by J. Schnakenberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book is devoted to the question: What fundamental ideas and concepts can phys ics contribute to the analysis of complex systems like those in biology and ecolo gy? The book originated from two lectures which I gave during the winter term 1974/75 and the summer term 1976 at the Rheinisch-Westfalische Technische Hoch schule in Aachen. The wish for a lecture with this kind of subject was brought forward by students of physics as well as by those from other disciplines like biology, physiology, and engineering sciences. The students of physics were look ing for ways which might lead them from their monodisciplinary studies into the interdisciplinary field between physics and life sciences. The students from the other disciplines suspected that there might be helpful physical concepts and ideas for the analysis of complex systems they ought to become acquainted with. It is clear that a lecture or a book which tries to realize the expectations of both these groups will meet with difficulties arising from the different train ings and background knowledge of physicists and nonphysicists. For the physicists, I have tried to give a brief description of the biological aspect and significance of a problem wherever it seems necessary and appropriate and as far as a physicist like me feels authorized to do so.
Identifiability And Regression Analysis Of Biological Systems Models
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Author : Paola Lecca
language : en
Publisher:
Release Date : 2020
Identifiability And Regression Analysis Of Biological Systems Models written by Paola Lecca and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Biochemistry categories.
This richly illustrated book presents the objectives of, and the latest techniques for, the identifiability analysis and standard and robust regression analysis of complex dynamical models. The book first provides a definition of complexity in dynamic systems by introducing readers to the concepts of system size, density of interactions, stiff dynamics, and hybrid nature of determination. In turn, it presents the mathematical foundations of and algorithmic procedures for model structural and practical identifiability analysis, multilinear and non-linear regression analysis, and best predictor selection. Although the main fields of application discussed in the book are biochemistry and systems biology, the methodologies described can also be employed in other disciplines such as physics and the environmental sciences. Readers will learn how to deal with problems such as determining the identifiability conditions, searching for an identifiable model, and conducting their own regression analysis and diagnostics without supervision. Featuring a wealth of real-world examples, exercises, and codes in R, the book addresses the needs of doctoral students and researchers in bioinformatics, bioengineering, systems biology, biophysics, biochemistry, the environmental sciences and experimental physics. Readers should be familiar with the fundamentals of probability and statistics (as provided in first-year university courses) and a basic grasp of R.
Microprobe Analysis Of Biological Systems
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Author : Thomas Hutchinson
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Microprobe Analysis Of Biological Systems written by Thomas Hutchinson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.
Microprobe Analysis of Biological Systems covers the proceedings of the 1980 Microprobe Analysis of Biological Systems conference held at Battelle Conference Center in Seattle, Washington. Most of the major laboratories in the field of biological microanalysis in the United States, England, Scotland, France, and Germany are represented. The conference presents the findings, theories, techniques, and procedures of the laboratory represented, no matter how tentative and exploratory. This book is divided into four parts encompassing 22 chapters that focus on biological applications of microprobe analysis. The introductory part describes the application of electron microprobe and X-ray microanalyses in studies of epithelial transport, avian salt gland, electrolyte transport, and acrosome reaction. The subsequent part covers the application of microprobe techniques in the analysis of cardiac, skeletal, vascular smooth, and freeze-dried muscles. It also describes a method for obtaining erythrocyte preparations for validating biological microprobe methods and the continuum-fluorescence effect on thick biological tissue. The method using freeze-substitution to localize calcium in quick-frozen tissue for X-ray microanalysis is also explained. The third part of the book tackles the principles, basic features, and applications of electron energy-loss spectroscopy. Discussions on the use of inner-shell signals for a quantitative local microanalysis technique; theoretical study of the energy resolution; and collection efficiency of a magnetic spectrometer are also included. The final part covers the elemental distribution in single erythrocytes using X-ray microanalysis. It also discusses the fundamentals of cryosectioning process for X-ray microanalysis of diffusible elements and the freezing behavior of a number of chemically different gels chosen for their partial resemblance to biological structures. Considerable chapters contain materials and methods, results, discussions, conclusions, and references. This book will be of value to scientists interested in elemental and ion transport within cells and between cells and extracellular compartments.