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Anti Aging Drug Discovery On The Basis Of Hallmarks Of Aging


Anti Aging Drug Discovery On The Basis Of Hallmarks Of Aging
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Anti Aging Drug Discovery On The Basis Of Hallmarks Of Aging


Anti Aging Drug Discovery On The Basis Of Hallmarks Of Aging
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Author : Sandeep Kumar Singh
language : en
Publisher: Academic Press
Release Date : 2022-07-19

Anti Aging Drug Discovery On The Basis Of Hallmarks Of Aging written by Sandeep Kumar Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-19 with Medical categories.


Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals. - Covers different aspects of anti-aging research, from foundational knowledge to future perspectives - Provides understanding on the different hallmarks of aging and how they can be applied in the development of anti-aging drugs - Discusses various anti-aging strategies, including telomerase reactivation, clearance of senescent cells, stem cell-based therapy, and others



A New Era In Alzheimer S Research


A New Era In Alzheimer S Research
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Author : Sandeep Kumar Singh
language : en
Publisher: Elsevier
Release Date : 2024-10-17

A New Era In Alzheimer S Research written by Sandeep Kumar Singh and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-17 with Medical categories.


A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals. - Contains basic knowledge about Alzheimer's disease and its causes and related pathology for a better understating of AD - Provides the multidisciplinary research on Alzheimer's disease in one source - Uniquely describes the details of the pathological, diagnostic, and preventive information for the potential development of novel anti-AD drugs - Includes hot topics, such as cerebrovascular pathology and lifestyle medicine, for the prevention of AD



Decoding Aging And Neurodegeneration


Decoding Aging And Neurodegeneration
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Author : Jan Barciszewski
language : en
Publisher: Springer Nature
Release Date : 2025-07-14

Decoding Aging And Neurodegeneration written by Jan Barciszewski and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-14 with Science categories.


This book focuses on the close relationship between aging and neurodegeneration. By highlighting the reversible nature of epigenetic changes, it provides a comprehensive overview of how these modifications can regulate gene expression without altering the DNA sequence, offering promising solutions for clinical intervention. Aging induces a gradual decline in cerebral function, leading to cognitive impairment, memory loss, motor dysfunction, and eventually functional decline and death. It is accompanied by the decline of organismal functions induced by whole genome alterations leading to neurodegeneration. Epigenetic modifications, including chromatin modifications, DNA methylation, and changes in regulatory RNAs, have a major impact on neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. The chapters in this book address critical issues such as the contribution of epigenetic mechanisms to aging, the interaction between genetic and environmental factors in neurodegeneration, and the potential for epigenetic therapies to delay aging and mitigate disease progression. This volume, part of the RNA Technologies book series, is an invaluable resource for researchers and advanced students in genetics and neuroscience. It provides a deep understanding of the molecular basis of neurodegenerative diseases and offers innovative strategies to address the challenges of aging and neurodegeneration.



The Vagus Immune Connection


The Vagus Immune Connection
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Author : J.P. Errico
language : en
Publisher: Simon and Schuster
Release Date : 2024-03-12

The Vagus Immune Connection written by J.P. Errico and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-12 with Health & Fitness categories.


A Simon & Schuster eBook. Simon & Schuster has a great book for every reader.



Anti Aging Pharmacology


Anti Aging Pharmacology
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Author : Vitaly Koltover
language : en
Publisher: Academic Press
Release Date : 2022-12-07

Anti Aging Pharmacology written by Vitaly Koltover and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-07 with Medical categories.


Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world's leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. - Includes updated information about current developments in anti-aging pharmacology - Offers practical advice on the applicability of certain healthspan-promoting medications - Discusses potential challenges related to the translation of anti-aging drugs in clinical practice



A First Course In Systems Biology


A First Course In Systems Biology
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Author : Eberhard Voit
language : en
Publisher: Taylor & Francis
Release Date : 2025-01-20

A First Course In Systems Biology written by Eberhard Voit and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-20 with Science categories.


A First Course in Systems Biology, Third Edition is an introduction to the growing field of systems biology for advanced undergraduates and graduate students. Its focus is the design and analysis of computational models and their applications to diverse biomedical phenomena, from simple networks and kinetics to complex pathway systems, signal transduction, personalized medicine, and interacting populations. The book begins with the fundamentals of computational modeling, then reviews features of the molecular inventories that bring biological systems to life and ends with case studies that reflect some of the frontiers in systems biology. In this way, the First Course provides the reader with a comprehensive background and with access to methods for executing standard tasks of biomedical systems analysis, exposure to the modern literature, and a foundation for launching into specialized projects that address biomedical questions with theoretical and computational means. This third edition has been thoroughly updated. It provides an introduction to agent-based and multiscale modeling, a deeper account of biological design principles, and the optimization of metabolic flux distributions. This edition also discusses novel topics of synthetic biology, personalized medicine, and virtual clinical trials that are just emerging on the horizon of this field.



Novel Chemical Microbiological And Physical Approaches In Food Safety Control Volume Ii


Novel Chemical Microbiological And Physical Approaches In Food Safety Control Volume Ii
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Author : Marco Iammarino
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-21

Novel Chemical Microbiological And Physical Approaches In Food Safety Control Volume Ii written by Marco Iammarino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-21 with Medical categories.


One of the most important emerging aspects that requires further research in food safety is the simultaneous presence of different contaminants (both microbiological and chemical) in the same food, the so-called “cocktail effect”. Large amounts of data are needed for these evaluations, since the huge number of interactions among different contaminants, which maybe hypothesized, have to be statistically evaluated before confirming an effective risk. Moreover, the range of food to take into account within these studies is very wide. In order to obtain comprehensive datasets, new approaches are needed. These approaches, composed of new analytical procedures, microbiological protocols and chemical/physical determinations, should allow the quick and economic obtainment of many parameters, possibly respecting the environment, in the “green chemistry” perspective.



Molecular Basis And Emerging Strategies For Anti Aging Interventions


Molecular Basis And Emerging Strategies For Anti Aging Interventions
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Author : Syed Ibrahim Rizvi
language : en
Publisher: Springer
Release Date : 2018-11-02

Molecular Basis And Emerging Strategies For Anti Aging Interventions written by Syed Ibrahim Rizvi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Medical categories.


This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.



Molecular Basis Of Nutrition And Aging


Molecular Basis Of Nutrition And Aging
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Author : Marco Malavolta
language : en
Publisher: Academic Press
Release Date : 2016-04-15

Molecular Basis Of Nutrition And Aging written by Marco Malavolta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-15 with Science categories.


Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. - Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging - Explores how nutritional factors are involved in the pathogenesis of aging across body systems - Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition



Ageing The Biology Of Senescence


Ageing The Biology Of Senescence
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Author : Alex Comfort
language : en
Publisher:
Release Date : 1964

Ageing The Biology Of Senescence written by Alex Comfort and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Aging categories.