Antibiofilm Strategies
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Antibiofilm Strategies
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Author : Katharina Richter
language : en
Publisher: Springer Nature
Release Date : 2022-09-28
Antibiofilm Strategies written by Katharina Richter and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-28 with Science categories.
Bacteria and fungi are able to aggregate together or on surfaces in densely packed microcolonies, facilitated by extracellular polymeric substances for cell protection and stability. These biofilms have proven to be extremely hard to eradicate and remove once established. In chronic infections, this condition can result in a high degree of morbidity and mortality as regular antibiotic treatments are ineffective against biofilms. In industrial facilities, the formation of biofilms can ruin production and result in enormous financial losses. In this book, the current state of antibiofilm research is presented by experts from around the world. Novel, cutting-edge techniques and new optimized strategies based on established methods are discussed in chapters focused on biofilm prevention, treatment and control for the application in clinical, industrial and veterinary settings. Antibiofilm strategies, such as chemical and enzymatic treatments, surface modification and coatings, quorum sensing inhibition and dispersal induction, phage therapy, cold plasma treatment, hyperbaric oxygen treatment, and metal-based nanomedicine are covered, among many others. This book contributes to the UN’s Sustainable Development Goal 3: Good Health and Well-Being and is a valuable resource for healthcare professionals, microbiologists, academics and for educators to inform curricula of universities and colleges.
Antimicrobials Antibiotic Resistance Antibiofilm Strategies And Activity Methods
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Author : Sahra Kırmusaoğlu
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-04-03
Antimicrobials Antibiotic Resistance Antibiofilm Strategies And Activity Methods written by Sahra Kırmusaoğlu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-03 with Medical categories.
To prevent bacterial adherence, invasion and infection, antimicrobials such as antibiotics are being used and vastly researched nowdays. Several factors such as natural selection, mutations in genes, the presence of efflux pumps, impermeability of the cell wall, structural changes in enzymes and receptors, biofilm formation, and quorum sensing cause microorganisms to develop resistance against antimicrobials. Isolates that synthesize extended spectrum-β-lactamases (ESBL), induced β-lactamases (IBL), carbapenamases, metallo-β-lactamases (MBLs), and New Delhi metallo-β-lactamases (NDM) have emerged. Determining virulence factors such as biofilms and the level of antimicrobial activities of antimicrobial agents alone and in combination with appropriate doses against microorganisms is very important for the diagnosis, inhibition, and prevention of microbial infection. The goal of this book is to provide information on all these topics.
Mechanisms Of Biofilm Development And Antibiofilm Strategies
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Author : Huancai Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-02
Mechanisms Of Biofilm Development And Antibiofilm Strategies written by Huancai Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-02 with Science categories.
Antimicrobials Antibiotic Resistance Antibiofilm Strategies And Activity Methods
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Author : Sahra Kırmusaoğlu
language : en
Publisher:
Release Date : 2019
Antimicrobials Antibiotic Resistance Antibiofilm Strategies And Activity Methods written by Sahra Kırmusaoğlu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Microbiology categories.
Understanding Antibiofilm Activity
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Author : Iram Liaqat
language : en
Publisher:
Release Date : 2022-06-30
Understanding Antibiofilm Activity written by Iram Liaqat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-30 with categories.
Biofilms have grown into a major issue that poses hazards to all life forms. This book reviews strategies which can be employed to combat biofilms. Chapter 1 demonstrates that microbial biofilms are generated when a polymeric matrix surrounds a collection of single or heterogeneous microbial organisms. Chapter 2 discusses how biofilm resistance to antimicrobial drugs has become a global problem for medical researchers. Chapter 3 discusses how even though antibiofilm tactics are helpful, they are still worth investigating because each strategy is limited by physiological parameters such as composition, osmolarity, and bacterial species. Chapter 4 reveals that biofilms are diverse microbial societies dwelling in diverse environments. Chapter 5 confers emerging biofilm eradication tendencies and tactics, as well as the treatment of biofilm-related medical problems. Chapter 6 examines how biofilm's pervasiveness makes its removal extremely challenging. Chapter 7 looks at a variety of recently discovered nano-established biomaterials as well as the approaches that are being used to create antibiofilm surfaces. Finally, Chapter 8 discusses how microbial biofilms, which are generated by the aggregation of single or varied microbial species encased in a polymeric matrix, are a frequent way for bacteria to shield themselves against environmental challenges and antibacterial treatments.
Antibiofilm Agents
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Author : Kendra P. Rumbaugh
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-05-08
Antibiofilm Agents written by Kendra P. Rumbaugh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-08 with Science categories.
This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.
Insights Into New Strategies To Combat Biofilms
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Author : Sujogya Kumar Panda
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-09
Insights Into New Strategies To Combat Biofilms written by Sujogya Kumar Panda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-09 with Science categories.
Emerging Concepts In Bacterial Biofilms
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Author : Sabu Thomas
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2020-01-10
Emerging Concepts In Bacterial Biofilms written by Sabu Thomas and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-10 with Science categories.
The ability to form biofilms is a universal attribute of bacteria. Bacteria are able to grow on almost every surface, forming these architecturally complex communities. In biofilms, the cells grow in multicellular aggregates, encased in an extracellular matrix produced by the bacteria themselves. They impact humans in many ways, and can form in natural, medical and industrial settings. For example, the formation of biofilms on medical devices such as catheters or implants often results in difficult-to-treat chronic infections. This book focuses on emerging concepts in bacterial biofilm research, such as the different mechanisms of biofilm formation in Gram negative and Gram positive bacteria, and the burden of biofilm associated infections. It also highlights the various anti-biofilm strategies that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.
New Insights On Biofilm Antimicrobial Strategies
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Author : Luís Melo
language : en
Publisher: MDPI
Release Date : 2021-08-17
New Insights On Biofilm Antimicrobial Strategies written by Luís Melo and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Medical categories.
Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.
Nanostructures For Antimicrobial And Antibiofilm Applications
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Author : Ram Prasad
language : en
Publisher: Springer Nature
Release Date : 2020-05-12
Nanostructures For Antimicrobial And Antibiofilm Applications written by Ram Prasad and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-12 with Science categories.
In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.