Antidepressant Treatment
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The Evidence Based Guide To Antidepressant Medications
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Author : Anthony J. Rothschild
language : en
Publisher: American Psychiatric Pub
Release Date : 2012
The Evidence Based Guide To Antidepressant Medications written by Anthony J. Rothschild and has been published by American Psychiatric Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
"The Evidence-Based Guide to Antipsychotic Medications" is a table-rich, comprehensive overview of current knowledge regarding the use of antipsychotic medications to treat a broad range of psychiatric conditions, from anxiety disorders to schizophrenia.
Antidepressant Treatment
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Author : John H. Greist
language : en
Publisher: Williams & Wilkins
Release Date : 1979
Antidepressant Treatment written by John H. Greist and has been published by Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.
Antidepressants
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Author : Olivier Berend
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-11-20
Antidepressants written by Olivier Berend and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-20 with Medical categories.
Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones, there is still much room for improvement. "Real" antidepressants, defined as those that "repair" or "improve" the depression-causing mechanism in the brains of depressed patients, have yet to be identified. This book presents current research on depression and antidepressants, including use of antidepressants in alcohol use disorders and pregnancy, treatment-resistant depression, and development of potential new medications.
Managing Treatment Resistant Depression
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Author : Joao Quevedo
language : en
Publisher: Academic Press
Release Date : 2022-03-31
Managing Treatment Resistant Depression written by Joao Quevedo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Science categories.
Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. Defines Treatment-Resistant Depression and Staging Treatment Intensity Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions Discusses the use of Ketamine and Esketamine for treatment-resistant depression
The Antidepressant Sourcebook
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Author : Andrew L. Morrison, M.D.
language : en
Publisher: Main Street Books
Release Date : 2010-02-24
The Antidepressant Sourcebook written by Andrew L. Morrison, M.D. and has been published by Main Street Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-24 with Self-Help categories.
In 1998, over 120 million prescriptions were written for antidepressants. That number is projected to rise by almost thirty million by the end of 2000. Despite this growing trend, many patients find that their doctors do not tell them all they need to know about the medications to make their treatments as successful as possible. The Antidepressant Sourcebook is the first place to turn for people taking antidepressants for the first time and for the millions who have already taken them. Here, in one concise reference, is all the reader needs to know, including what to talk about with the doctor, how to start and stop medications, and what to expect in the course of treatment. It is a written complement to what the doctor tells you. It answers every question a patient might have: How do I know if I'm on the right medication? Will my antidepressant interact with other medications I'm taking? Can I take it while pregnant? Will it change my personality? Do I need psychotherapy? If you or someone you love is taking antidepressants for depression, an anxiety disorder, or any other reason, your concerns will be addressed here. The Antidepressant Sourcebook is the most comprehensive primer you can own, offering hands-on advice and clear information. It's required reading for anyone who is taking or thinking about taking antidepressants.
Depression From Psychopathology To Pharmacotherapy
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Author : J.F. Cryan
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010-11-17
Depression From Psychopathology To Pharmacotherapy written by J.F. Cryan and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-17 with Medical categories.
Despite the availability of antidepressants for over 40 years, a substantial proportion of depressed patients do not respond adequately to treatment. Failure to respond effectively to treatment contributes to physical ill-health and psychiatric morbidity, often resulting in premature death of the depressed patient. The purpose of this volume is to consider the possible reasons for the limitations of the currently available antidepressants, to examine the advances in our understanding of the psychopathology of depression and how such knowledge may assist in the discovery of new methods of treatment. Leading international experts in this field discuss the possible underlying reasons for depression and limitations of current antidepressants. Opportunities for novel therapeutic approaches to dysfunctional circadian rhythms and mood disorders as well as current status and future perspectives for optimizing antidepressant management of depression are reviewed. This publication illustrates the breadth of the latest research and is valuable reading for psychiatrists, neuroscientists and pharmacologists.
Next Generation Antidepressants
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Author : Chad E. Beyer
language : en
Publisher: Cambridge University Press
Release Date : 2010-05-20
Next Generation Antidepressants written by Chad E. Beyer and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-20 with Medical categories.
The World Health Organization defines depression as a primary contributor to the global burden of disease and predicts it will become the second leading cause of death by 2020. The need to develop effective therapies has never been so pressing. Current antidepressant drugs have several limitations. This 2010 book looks at the future of mood-disorder research, covering the identification of new therapeutic targets, establishing new preclinical models, new medicinal chemistry opportunities, and fostering greater understanding of genetic influences. These strategies are likely to help build a better picture of the disease process, and lead to new opportunities for patient stratification and treatment. The ultimate goal for this strand of research is to develop more personalized and effective treatments for this chronic and debilitating condition. This is essential reading for all those involved in psychopharmacologic drug development, and mental health clinicians seeking a preview of discoveries soon to influence their practice.
Antidepressants
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Author : B. E. Leonard
language : en
Publisher: Springer Science & Business Media
Release Date : 2001
Antidepressants written by B. E. Leonard and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
Important clinical issues as the outcome of long term treatment with antidepressants, the time of onset of the antidepressant response and the limitations of the antidepressants currently available are covered in this monograph. Leading researchers in the area of clinical and experimental psychopharmacology critically assess the progress in their specialist fields. The mechanisms of action of antidepressants are considered, followed by clinical research into the role of the hypothalamic-pituitary-adrenal axis and the immune system in the biology of depression and in response to treatment. The final chapter deals with the important chemical entities now undergoing development as antidepressants. The purpose of this monograph is not only to inform but also to stimulate research into the biology of depression and the mechanisms behind the action of effective antidepressants. This monograph is of interest to psychiatrists, psychologists, pharmacologists, neuroscientists and endocrinologists.
Pharmacotherapy For Depression And Treatment Resistant Depression
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Author : George I. Papakostas
language : en
Publisher: World Scientific
Release Date : 2010
Pharmacotherapy For Depression And Treatment Resistant Depression written by George I. Papakostas and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
1. Major depressive disorder and treatment-resistant depression. 1.1. Major depressive disorder. 1.2. Treatment-resistant depression (TRD). 1.3. Demographic and clinical risk factors for resistant depression -- 2. Monoaminergic-based strategies : "Single-acting" agents. 2.1. Monoamine precursors for depression. 2.2. Selective serotonin reuptake inhibitors (SSRIs). 2.3. Serotonin receptor antagonists and agonists. 2.4. Serotonin reuptake enhancers. 2.5. [symbol]-2 adrenergic receptor agonists and antagonists. 2.6. Norepinephrine reuptake inhibitors (NRIs). 2.7. Selective [symbol] adrenergic receptor agonists. 2.8. Dopamine-selective agents -- 3. Monoaminergic-based strategies : "Dual-acting" agents. 3.1. Tricyclic antidepressants (TCAs). 3.2. Serotonin-norepinephrine reuptake inhibitors (SNRIs). 3.3. 5HT-2 and [symbol]-2 adrenergic receptor antagonists. 3.4. Norepinephrine-dopamine reuptake inhibitors -- 4. Monoaminergic-based strategies : "Triple-acting " agents. 4.1. Monoamine oxidase inhibitors (MAOIs). 4.2. Serotonin-norepinephrine-dopamine reuptake inhibitors. 4.3. Catechol-O-methyltransferase (COMT) inhibitors -- 5. Polypharmacy from the onset of treatment. 5.1. Adjunctive treatment with monoaminergic agents. 5.2. Adjunctive treatment with neuroendocrine agents. 5.3. Other agents -- 6. Polypharmacy strategies for treatment-resistant depression. 6.1. Adjunctive treatment with monoaminergic agents. 6.2. Adjunctive treatment with neuroendocrine agents. 6.3. Other agents -- 7. Monotherapy strategies for resistant depression. 7.1. Increasing the dose of antidepressants. 7.2. Switching antidepressants due to lack of efficacy -- 8. Non-pharmacologic approaches for resistant depression. 8.1. Device-based therapies. 8.2. Psychotherapy. 8.3. Exercise. 8.4. Yoga and meditation -- 9. Pharmacotherapy of relapse/recurrence prevention and treatment. 9.1. Antidepressant continuation and maintenance therapy studies. 9.2. Special topics in the pharmacotherapy of relapse prevention. 9.3. Treatment of depressive relapse/recurrence -- 10. Pharmacologic strategies to enhance antidepressant tolerability. 10.1. Adjunctive therapy. 10.2. Switching antidepressants due to intolerance -- 11. Agents operating on non-monoaminergic neurotransmitter systems. 11.1. GABA-ergic treatments. 11.2. Glycine and glutamate-based treatments. 11.3. Agents with combined GABA-ergic and glutamatergic activity. 11.4. Other anticonvulsants. 11.5. Neurokinin-receptor antagonists. 11.6. Nicotinic receptor-based treatments. 11.7. Cannabinoids and endocannabinoids. 11.8. Opioidergic therapies. 11.9. Other neurotransmitter systems -- 12. Neuroendocrine-based agents. 12.1. Hypothalamic-pituitary-gonadal axis (HPG). 12.2. Hypothalamic-pituitary-adrenal axis (HPA). 12.3. Hypothalamic-pituitary-thyroid axis (HPT). 12.4. Melatonin and melatonergic agents. 12.5. Other hormones -- 13. Metabolic-based and other agents. 13.1. Metabolic-based agents. 13.2. Agents with unknown mechanism of action -- 14. Biological predictors, moderators, and mediators of efficacy. 14.1. Definition and significance of mediators of outcome. 14.2. Genetic markers. 14.3. Neurophysiology. 14.4. Molecular biology
Treatment Resistant Depression
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Author : Siegfried Kasper
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-15
Treatment Resistant Depression written by Siegfried Kasper and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-15 with Medical categories.
Treatment-resistant Depress Successful management of patients with treatment-resistant depression requires a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of treatment-resistant depression originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors and gene variants have been identified as accounting for 50% of the variance in the clinical outcomes of antidepressant treatments. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, suggests that genetic prediction of treatment resistance could become a widespread clinical reality within a few years. Most patients with treatment-resistant depression will be treated pharmacologically, so three chapters review the latest evidence for pharmacological best practice in switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, explaining that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in treatment-resistant depression and summarizes general therapeutic principles. Essential reading for all psychiatrists managing patients with this distressing disorder.