Antifungal Drugs
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Antifungal Drug Discovery New Theories And New Therapies
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Author : Chaminda Jayampath Seneviratne
language : en
Publisher: Frontiers Media SA
Release Date : 2016-09-13
Antifungal Drug Discovery New Theories And New Therapies written by Chaminda Jayampath Seneviratne and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-13 with Microbiology categories.
Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.
New Approaches For Antifungal Drugs
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Author : FERNANDES
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09
New Approaches For Antifungal Drugs written by FERNANDES and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Science categories.
Antifungal Therapy Second Edition
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Author : Mahmoud A. Ghannoum
language : en
Publisher: CRC Press
Release Date : 2019-03-08
Antifungal Therapy Second Edition written by Mahmoud A. Ghannoum and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-08 with Medical categories.
This new edition of Antifungal Therapy aims at providing concise, practical, need-to-know information for busy physicians dealing with fungal infections, such as infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. It provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment including the basics of clinical mycology, management insights for various infections, evidence-based treatment recommendations, and helpful tables summarizing currently available pharmacokinetics data. Key Features • Features useful information on administration, dosage and pharmacology of antifungal drugs that can be difficult to use in clinical practice • Contains common Clinical Questions & Answers to highlight frequently encountered patient issues • Covers clinical mycology essentials in addition to antifungal treatment to create a well-rounded reference • Presents illustrations and clinical photos in full color to elucidate the concepts • Provides detailed evidence of treatment recommendations
Antifungal Agents
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Author : Erika J. Ernst
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Antifungal Agents written by Erika J. Ernst and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.
A collection of state-of-the-art molecular methods for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents. The protocols follow the successful Methods in Molecular MedicineTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Antifungal Agents: Methods and Protocols offers clinician-scientists, microbiologists and molecular biologists the productive tools they need today to understand and successfully develop new therapeutic agents for yeast, mold, and fungal infections.
Recent Trends In Antifungal Agents And Antifungal Therapy
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Author : Amit Basak
language : en
Publisher: Springer
Release Date : 2016-09-21
Recent Trends In Antifungal Agents And Antifungal Therapy written by Amit Basak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-21 with Science categories.
Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students.
Antifungal Drugs
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Author : Vassil St Georgiev
language : en
Publisher:
Release Date : 1989
Antifungal Drugs written by Vassil St Georgiev and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.
Antifungal Drug Discovery New Theories And New Therapies
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Author :
language : en
Publisher:
Release Date : 2016
Antifungal Drug Discovery New Theories And New Therapies written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.
Antifungal Agents
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Author : Ernst M. Jucker
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Antifungal Agents written by Ernst M. Jucker and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This second volume of PDR SPECIAL TOPICS contains five review articles, covering nearly the entire field of fungal diseases in humans as well as therapeutic approaches. The main emphasis of the book lies in antifungal therapy: the most relevant information on the present state of the art of antifungal chemotherapy for dermatomycoses, subcutaneous and invasive mycoses is summarized, and open questions and unsolved problems are presented. The book is ideal for both the practitioner as well as advanced student.
Vaccines Immunotherapy And New Antifungal Therapy Against Fungi Updates In The New Frontier
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Author : Carlos P. Taborda
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-15
Vaccines Immunotherapy And New Antifungal Therapy Against Fungi Updates In The New Frontier written by Carlos P. Taborda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-15 with categories.
Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. Also, it is growing the interest over new drugs development as second choice for treatment when traditional chemotherapy fail. This Research Topic will detail the exciting progress in developing vaccines, immunotherapy and new drugs for fungi.
New Approaches For Antifungal Drugs
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Author : Prabhavathi B. Fernandes
language : en
Publisher: Birkhauser
Release Date : 1992-01-01
New Approaches For Antifungal Drugs written by Prabhavathi B. Fernandes and has been published by Birkhauser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-01 with Antifungal agents categories.
Reviews research on the chemotherapy of fungal diseases, which has progressed at a much slower rate than that against bacterial diseases. Emphasizes the search during the past decade for selective targets of therapeutic agents, selection being the main difficulty because of the eukaryotic nature of fungi. In addition to several novel drugs, considers structures, processes, and proteins as potential targets; and new approaches such as antifungal agents from plants, and genetic methods of drug discovery. Annotation copyrighted by Book News, Inc., Portland, OR