Antiviral Chemotherapy 4
DOWNLOAD
Download Antiviral Chemotherapy 4 PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Antiviral Chemotherapy 4 book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Antiviral Chemotherapy 4
DOWNLOAD
Author : John Mills
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Antiviral Chemotherapy 4 written by John Mills and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
The three years since our last conference in San Francisco have again seen a dramatic expansion of the number of antivirals either licensed or in the late stages of clinical trials. d4T is now licensed for HIV infection, famciclovir and the oral pro-drug of acyclovir, valacyclovir, are now licensed for VZV infections in some countries. Moreover. oral ganciclovir, cidofovir, and sorivudine are not far behind. Clinical trials with the second-site reverse transcriptase inhibitors and the protease inhibitors for HlV infection are proceeding rapidly and on a broad scale, and the preliminary results would suggest that several of these classes of drugs will be licensed as well. Despite this optimism, however, there is increasing evidence that antiviral-resistant strains of pathogenic viruses will be a significant problem, perhaps especially with therapy of HIV infection, and there remains a desperate need for improved drugs (with either improved efficacy or decreased toxicity, or both) for CMV and HIV infections. This book is the edited proceedings of the Fourth Triennial Conference on Antiviral Chemotherapy, held in San Francisco, in November 1994. The conference was sponsored by the University of California, San Francisco, and co-sponsored by the International Society for Antiviral Research (ISAR), the Macfarlane Burnet Centre for Medical Research in Melbourne, Australia, and the Australian National Centre for HIV Virology Research. The conference had been organized to present an overview of the field of antiviral chemotherapy.
Antiviral Chemotherapy
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1993
Antiviral Chemotherapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with categories.
Proceedings Of The Conference New Directions In Antiviral Chemotherapy
DOWNLOAD
Author : Conference on Antiviral Chemotherapy. 1, 1985, San Francisco, Calif..
language : en
Publisher:
Release Date : 1986
Proceedings Of The Conference New Directions In Antiviral Chemotherapy written by Conference on Antiviral Chemotherapy. 1, 1985, San Francisco, Calif.. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Antiviral Chemotherapy 5
DOWNLOAD
Author : John Mills
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Antiviral Chemotherapy 5 written by John Mills and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Scientists and clinicians attending the last "New Directions in Antiviral Therapy" conference in late 1994 could hardly have predicted the revolution in the management of patients with HIV infection that has occurred since. Two new classes of antiretrovirals have been licensed, the second-site RT inhibitors and the protease inhibitors; the long in cubation period of active HIV infection, when the infection is clinically latent, is now un derstood to be a period of intense viral replication and turnover of CD4 lymphocytes; measurements of HI V RNA concentration in plasma have been shown to be essential tools for monitoring the course of HIV infection, deciding when to treat, and assessing the re sults of treatment; and finally, combinations of antiretrovirals, particularly combinations including protease inhibitors, have been shown to have dramatically beneficial effects on patients with HIV infection. These advances, coupled with new drugs for the management of herpesvirus infections, have made dramatic differences in the quality and length of life of HIV-infected patients. Additional advances have been made since 1994 in the prevention or management of influenza virus (zanamavir), respiratory syncytial virus (palvizumab), hepatitis B virus (lamivudine and famciclovir), and enterovirus infections (pleconaril). It is difficult to re member that only slightly more than a decade ago there were only a handful of antiviral agents available (none of which were antiretrovirals), and a number of those were either highly toxic, of dubious efficacy, or both.
Antiviral Chemotherapy
DOWNLOAD
Author : Hans W. Doerr
language : en
Publisher:
Release Date : 1998
Antiviral Chemotherapy written by Hans W. Doerr and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Antiviral agents categories.
Antiviral chemotherapy is still far away from the high success rate of antibacterial therapy, but the situation is improving. In recent years, several new substances have been found to be active against a variety of viral infections. This special issue presents the current possibilities and the most promising new approaches for treatment of AIDS, hepatitis B and C, papillomas and infections by members of the Herpesviridae family. Most antiviral drugs continue to be nucleoside or nucleotide analogs. Lamivudine, e.g., originally developed against HIV, and famciclovir, developed against herpesviruses, have both turned out to be very effective against hepatitis B virus. Several new substances which have proven active against HIV, cytomegalovirus, varizella/zoster virus or herpes simplex virus, are described in detail. No adequate therapy currently exists against hepatitis C, but the expression of some potential target molecules of the virus opens up ways to search for specific inhibitors. Further topics considered are the use of immunostimulatory drugs, and the role of viral and cellular resistance mechanisms in long-term antiviral therapy. Providing the latest data on the usefulness and limitations of licensed and experimental drugs, this issue will be of interest to all medical virologists and infectious disease specialists as well as to hepatologists and transplantation specialists.
Antiviral Chemotherapy
DOWNLOAD
Author : Richard Challand
language : en
Publisher:
Release Date : 1997
Antiviral Chemotherapy written by Richard Challand and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
A textbook for an upper-level or graduate course for students with a background in chemistry or biochemistry. Traces the history of antivirals and presents the current understanding of viral biochemistry, the mechanisms of small molecules and their development as drugs, and the application of various types of chemical therapies. Includes a glossary without pronunciation. Annotation copyrighted by Book News, Inc., Portland, OR
Proceedings Of The Conference New Directions In Antiviral Chemotherapy
DOWNLOAD
Author : John Mills
language : en
Publisher:
Release Date : 1986
Proceedings Of The Conference New Directions In Antiviral Chemotherapy written by John Mills and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Clinical Use Of Antiviral Drugs
DOWNLOAD
Author : Erik de Clercq
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Clinical Use Of Antiviral Drugs written by Erik de Clercq and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Antiviral chemotherapy has come of age, and, after an initial slow pro gress, the development of new antiviral agents has proceeded at a more rapid pace and the perspectives for their clinical use have increased considerably. Now, 25 years after the first antiviral assay (idoxuridine) was introduced in the clinic, it is fitting to commemorate the beginning of the antivirals' era. In its introductory chapter B.E. Juel-Jensen touches on what may be con sidered as five of the most fundamental requirements of an antiviral drug : efficacy, relative non-toxicity, easy solubility, ready availability and rea sonable cost. Surely, the antiviral drugs that have so far been used in the clinic could still be improved upon as one or more of these five essential demands are concerned. How is all began is narrated by W.H. Prusoff. The first antiviral drugs to be used in humans were methisazone and idoxuridine, the former, which is now of archival interest, in the prevention of smallpox, the latter, which was approved for clinical use in the United States in 1962, for the topical treatment of herpetic keratitis. In terms of potency, also because of solubility reasons, idoxuridine has been superseded by trifluridine in the topical treatment of herpes simplex epithelial keratitis. H.E. Kaufman did not find trifluridine or acyclovir ef fective in the treatment of deep stromal keratitis or iritis and he reckons that other antiviral drugs (i.e. bromovinyldeoxyuridine) would not be effec tive either.
Antiviral Chemotherapy
DOWNLOAD
Author : K. K. Gauri
language : en
Publisher:
Release Date : 1981
Antiviral Chemotherapy written by K. K. Gauri and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Antiviral agents categories.
Antiviral Agents
DOWNLOAD
Author : Hugh J. Field
language : en
Publisher:
Release Date : 1988
Antiviral Agents written by Hugh J. Field and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Antiviral agents categories.