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Antiviral Therapy

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New Concepts Of Antiviral Therapy

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Author : Elke Bogner
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-31

New Concepts Of Antiviral Therapy written by Elke Bogner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-31 with Medical categories.

Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Includes contributions by acknowledged experts; the book will serve as a compendium for R&D and educational professionals, and be of value for students.

Practical Guidelines In Antiviral Therapy

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Author : G.J. Galasso
language : en
Publisher: Elsevier
Release Date : 2002-01-21

Practical Guidelines In Antiviral Therapy written by G.J. Galasso and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-21 with Medical categories.

This text was developed with the practicing physician in mind, however, it will be of considerable interest to the virologist, pharmacologist, chemist and all scientists interested in antiviral agents. Progress in the field of antiviral development is now moving rapidly and there is hope that one day there will be successful treatment modalities for most viral diseases. This work contains contributions from experts around the world, capturing worldwide practices. An online version providing the current status of antiviral research is planned for the near future.

Antiviral Therapy

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Author : Dr Eddie Blair
language : en
Publisher: Taylor & Francis
Release Date : 2023-05-31

Antiviral Therapy written by Dr Eddie Blair and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-31 with Science categories.

A concise summary of vital information on drug targets and current therapy regimes for all of the major viral infections. The book brings together in a single volume aspects of antiviral therapy from diverse areas of research and practice, providing up-to-date coverage of recent developments. Starting from an overview of the history of antiviral chemotherapy, the book goes on to describe the development of drugs against HIV, herpesvirus, respiratory viruses, papillomaviruses and hepatitis virus infections. The drugs currently available are reviewed and possible therapies and drug targets for future prophylactic and therapeutic use are discussed.

Antiviral Drugs

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Author : Patrick Arbuthnot
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-14

Antiviral Drugs written by Patrick Arbuthnot and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-14 with Medical categories.

The articles that appear in Antiviral Drugs - Aspects of Clinical Use and Recent Advances cover several topics that reflect the varied mechanisms of viral disease pathogenesis and treatment. Clinical management and new developments in the treatment of virus-related diseases are the two main sections of the book. The first part reviews the treatment of hepatitis C virus infection, the management of virus-related acute retinal necrosis, the use of leflunomide therapy in renal transplant patients, and mathematical modeling of HIV-1 treatment responses. Basic research topics are dealt with in the second half of the book. New developments in the treatment of the influenza virus, the use of animal models for HIV-1 drug development, the use of single chain camelid antibodies against negative strand RNA viruses, countering norovirus infection, and the use of plant extracts to treat herpes simplex virus infection are described. The content of the book is not intended to be comprehensive, but aims to provide the reader with insights into selected aspects of established and new viral therapies.

Antiviral Therapy

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Author : E. Blair
language : en
Publisher: Springer
Release Date : 1998

Antiviral Therapy written by E. Blair and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Antiviral agents categories.

Antiviral Strategies

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Author : Hans-Georg Kräusslich
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-02

Antiviral Strategies written by Hans-Georg Kräusslich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-02 with Medical categories.

A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance; thus, monitoring and overcoming resistance has become a most important clinical paradigm of antiviral therapy. This calls for cautious use of antiviral drugs and implementation of combination therapies. In parallel, efforts in drug discovery have to be continued to develop compounds with novel mode-of-action and activity against resistant strains. This book reviews the current status of antiviral therapy, from the roads to development of new compounds to their clinical use and cost effectiveness. Individual chapters address in more detail all available drug classes and outline new approaches currently under development.

Antiviral Therapy

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Author : E. Blair
language : en
Publisher: Taylor & Francis
Release Date : 1998

Antiviral Therapy written by E. Blair and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.

Clinical Use Of Antiviral Drugs

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Author : Erik de Clercq
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Clinical Use Of Antiviral Drugs written by Erik de Clercq and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Antiviral chemotherapy has come of age, and, after an initial slow pro gress, the development of new antiviral agents has proceeded at a more rapid pace and the perspectives for their clinical use have increased considerably. Now, 25 years after the first antiviral assay (idoxuridine) was introduced in the clinic, it is fitting to commemorate the beginning of the antivirals' era. In its introductory chapter B.E. Juel-Jensen touches on what may be con sidered as five of the most fundamental requirements of an antiviral drug : efficacy, relative non-toxicity, easy solubility, ready availability and rea sonable cost. Surely, the antiviral drugs that have so far been used in the clinic could still be improved upon as one or more of these five essential demands are concerned. How is all began is narrated by W.H. Prusoff. The first antiviral drugs to be used in humans were methisazone and idoxuridine, the former, which is now of archival interest, in the prevention of smallpox, the latter, which was approved for clinical use in the United States in 1962, for the topical treatment of herpetic keratitis. In terms of potency, also because of solubility reasons, idoxuridine has been superseded by trifluridine in the topical treatment of herpes simplex epithelial keratitis. H.E. Kaufman did not find trifluridine or acyclovir ef fective in the treatment of deep stromal keratitis or iritis and he reckons that other antiviral drugs (i.e. bromovinyldeoxyuridine) would not be effec tive either.

Antiviral Drugs

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Author : Wieslaw M. Kazmierski
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-23

Antiviral Drugs written by Wieslaw M. Kazmierski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-23 with Medical categories.

This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.

Antiviral Chemotherapy

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Author : Hans W. Doerr
language : en
Publisher:
Release Date : 1998

Antiviral Chemotherapy written by Hans W. Doerr and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Antiviral agents categories.

Antiviral chemotherapy is still far away from the high success rate of antibacterial therapy, but the situation is improving. In recent years, several new substances have been found to be active against a variety of viral infections. This special issue presents the current possibilities and the most promising new approaches for treatment of AIDS, hepatitis B and C, papillomas and infections by members of the Herpesviridae family. Most antiviral drugs continue to be nucleoside or nucleotide analogs. Lamivudine, e.g., originally developed against HIV, and famciclovir, developed against herpesviruses, have both turned out to be very effective against hepatitis B virus. Several new substances which have proven active against HIV, cytomegalovirus, varizella/zoster virus or herpes simplex virus, are described in detail. No adequate therapy currently exists against hepatitis C, but the expression of some potential target molecules of the virus opens up ways to search for specific inhibitors. Further topics considered are the use of immunostimulatory drugs, and the role of viral and cellular resistance mechanisms in long-term antiviral therapy. Providing the latest data on the usefulness and limitations of licensed and experimental drugs, this issue will be of interest to all medical virologists and infectious disease specialists as well as to hepatologists and transplantation specialists.

Antiviral Therapy

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