New Concepts Of Antiviral Therapy


New Concepts Of Antiviral Therapy
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New Concepts Of Antiviral Therapy


New Concepts Of Antiviral Therapy
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Author : Elke Bogner
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-31

New Concepts Of Antiviral Therapy written by Elke Bogner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-31 with Medical categories.


Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Includes contributions by acknowledged experts; the book will serve as a compendium for R&D and educational professionals, and be of value for students.



Antiviral Drug Strategies


Antiviral Drug Strategies
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Author : Erik De Clercq
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-08

Antiviral Drug Strategies written by Erik De Clercq and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-08 with Medical categories.


By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, neuraminidases, RNA polymerases, helicases and primases, as well as their known inhibitors. The final section contains several cases studies of recent successful antiviral drug development. Edited by Erik de Clercq, the world authority on small molecule antiviral drugs, who has developed more new antivirals than anyone else.



Antiviral Drugs


Antiviral Drugs
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Author : Wieslaw M. Kazmierski
language : en
Publisher: John Wiley & Sons
Release Date : 2011-07-08

Antiviral Drugs written by Wieslaw M. Kazmierski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-08 with Medical categories.


This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.



Antiviral Chemotherapy 5


Antiviral Chemotherapy 5
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Author : John Mills
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Antiviral Chemotherapy 5 written by John Mills and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Scientists and clinicians attending the last "New Directions in Antiviral Therapy" conference in late 1994 could hardly have predicted the revolution in the management of patients with HIV infection that has occurred since. Two new classes of antiretrovirals have been licensed, the second-site RT inhibitors and the protease inhibitors; the long in cubation period of active HIV infection, when the infection is clinically latent, is now un derstood to be a period of intense viral replication and turnover of CD4 lymphocytes; measurements of HI V RNA concentration in plasma have been shown to be essential tools for monitoring the course of HIV infection, deciding when to treat, and assessing the re sults of treatment; and finally, combinations of antiretrovirals, particularly combinations including protease inhibitors, have been shown to have dramatically beneficial effects on patients with HIV infection. These advances, coupled with new drugs for the management of herpesvirus infections, have made dramatic differences in the quality and length of life of HIV-infected patients. Additional advances have been made since 1994 in the prevention or management of influenza virus (zanamavir), respiratory syncytial virus (palvizumab), hepatitis B virus (lamivudine and famciclovir), and enterovirus infections (pleconaril). It is difficult to re member that only slightly more than a decade ago there were only a handful of antiviral agents available (none of which were antiretrovirals), and a number of those were either highly toxic, of dubious efficacy, or both.



Antivirals Advances In Research And Application 2011 Edition


Antivirals Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09

Antivirals Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.


Antivirals: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Antivirals. The editors have built Antivirals: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antivirals in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antivirals: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Combination Therapy Of Aids


Combination Therapy Of Aids
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Author : Erik De Clercq
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06

Combination Therapy Of Aids written by Erik De Clercq and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


An extensive assessment of combination therapy of AIDS. Main focus is put on the Highly Active Antiretroviral Therapy (HAART) but other therapies like salvage therapy are also discussed. The chapters cover efficacy, treatment, causes of treatment failure, clinical care, guidelines, pharmacology. The volume closes with an outlook on future perspectives.



Psychosocial And Public Health Impacts Of New Hiv Therapies


Psychosocial And Public Health Impacts Of New Hiv Therapies
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Author : David G. Ostrow
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-02-28

Psychosocial And Public Health Impacts Of New Hiv Therapies written by David G. Ostrow and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-02-28 with Medical categories.


This volume addresses the issues surrounding combination drug therapies and the treatment of HIV/AIDS. Each chapter, written by a leading researcher, provides the latest information on the pharmacology, clinical use - including adherence to treatment guidelines - prevention implications, mental health ramifications, and ethical and policy issues. By highlighting context as well as content, and focusing on general principles in addition to specific details, this necessary text remains relevant and valuable for future treatment advances.



Consolidated Guidelines On The Use Of Antiretroviral Drugs For Treating And Preventing Hiv Infection


Consolidated Guidelines On The Use Of Antiretroviral Drugs For Treating And Preventing Hiv Infection
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Author : World Health Organization
language : en
Publisher:
Release Date : 2016

Consolidated Guidelines On The Use Of Antiretroviral Drugs For Treating And Preventing Hiv Infection written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with AIDS (Disease) categories.


These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.



Antiviral Drugs


Antiviral Drugs
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Author : Patrick Arbuthnot
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-14

Antiviral Drugs written by Patrick Arbuthnot and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-14 with Medical categories.


The articles that appear in Antiviral Drugs - Aspects of Clinical Use and Recent Advances cover several topics that reflect the varied mechanisms of viral disease pathogenesis and treatment. Clinical management and new developments in the treatment of virus-related diseases are the two main sections of the book. The first part reviews the treatment of hepatitis C virus infection, the management of virus-related acute retinal necrosis, the use of leflunomide therapy in renal transplant patients, and mathematical modeling of HIV-1 treatment responses. Basic research topics are dealt with in the second half of the book. New developments in the treatment of the influenza virus, the use of animal models for HIV-1 drug development, the use of single chain camelid antibodies against negative strand RNA viruses, countering norovirus infection, and the use of plant extracts to treat herpes simplex virus infection are described. The content of the book is not intended to be comprehensive, but aims to provide the reader with insights into selected aspects of established and new viral therapies.



Disease Control Priorities Third Edition Volume 6


Disease Control Priorities Third Edition Volume 6
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Author : King K. Holmes
language : en
Publisher: World Bank Publications
Release Date : 2017-11-06

Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-06 with Medical categories.


Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.