Application And Integration Of Omics Powered Diagnostics In Clinical And Public Health Microbiology
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Application And Integration Of Omics Powered Diagnostics In Clinical And Public Health Microbiology
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Author : Jacob Moran-Gilad
language : en
Publisher: Springer Nature
Release Date : 2021-05-24
Application And Integration Of Omics Powered Diagnostics In Clinical And Public Health Microbiology written by Jacob Moran-Gilad and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-24 with Science categories.
Various “omics” methods have recently revolutionized molecular diagnostics. Next-generation sequencing (NGS) makes it possible to sequence a human genome in just one day. Whole genome sequencing (WGS) greatly improves the ability to investigate the outbreaks of numerous pathogens. Metagenomics helps to analyze the microbiome, which aids greatly in identifying the pathogenesis of infectious diseases. Proteomic-based methods, namely matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF-MS), have a promising role in identifying myctobacteria and fungi, and predicting antimicrobial resistance. While there are numerous scientific publications on “omics” applications for microbiology, there are relatively few books that review this topic from a clinical diagnostics perspective. This book looks at this field from a holistic viewpoint, instead of limiting by type of “omics” technology, in order to cover the body of knowledge needed for practitioners and academics interested in clinical and public health microbiology. Additionally, it addresses the management, economical, regulatory and operational aspects of integrating these technologies into routine diagnostics.
One Health
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Author : Joana C. Prata
language : en
Publisher: Academic Press
Release Date : 2022-04-27
One Health written by Joana C. Prata and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-27 with Medical categories.
One Health: Challenges for the 21st Century is a transdisciplinary approach to health, considering the interdependency of human, animal, and environmental health. This approach to health promotion and disease prevention calls for integrative and interdisciplinary cooperation. From zoonotic diseases to environmental degradation, this book introduces core concepts of the One Health approach by presenting focal key challenges. The objective of this book is not centered solely on epidemiologic interactions of infectious diseases but also on the environmental and ecological implications of current major threats. Written by international experts, the ten chapters provide a comprehensive approach consisting of core concepts, practical examples, and applications that align with key challenges to public health. Therefore, this book is a valuable resource for public health professionals, veterinarians, physicians, environmental researchers, policymakers, and other professionals who seek to understand the overarching complexities of health. - Examines the interconnection between humans, animals and the environment and how those relationships impact prevention, early detection, containment, and response to public health risks - Offers concise and comprehensive coverage of the One Health concept, application to key public health challenges, and current and future developments - Presents insights from an interdisciplinary group of international experts, containing examples to illustrate One Health framework and issues
Maldi Tof Ms In Microbiological Diagnostics Future Applications Beyond Identification
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Author : Karsten Becker
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-18
Maldi Tof Ms In Microbiological Diagnostics Future Applications Beyond Identification written by Karsten Becker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-18 with Science categories.
Manual Of Molecular Microbiology
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Author : Randall T. Hayden
language : en
Publisher: John Wiley & Sons
Release Date : 2025-05-30
Manual Of Molecular Microbiology written by Randall T. Hayden and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-30 with Medical categories.
Your essential guide to design, operation, management, and health care integration of the modern molecular microbiology laboratory This comprehensive resource offers definitive guidance on the operational and interpretive aspects of clinical molecular microbiology. Tailored for medical laboratory professionals, it provides practical “how-to” guidance for establishing, maintaining, and advancing molecular microbiology testing services and details the unique expertise required to support infectious disease diagnostics. The Manual offers a clear and practical roadmap for topics ranging from selecting appropriate technologies, instruments, and analytic pipelines to navigating complex interpretive challenges and positioning diagnostic testing services for future clinical and population health needs. Beginning with foundational technologies and their clinical applications, this book offers accessible overviews of each method’s potential, implications, and emerging roles. Subsequent sections dive meticulously into details of laboratory setup, design, and operations, empowering readers with hands-on insights for routine and advanced testing methods, including advanced sequencing technologies. It also tackles the nuanced challenges of interpreting and reporting results from cutting-edge diagnostics, including those focused on antimicrobial resistance and metagenomics. The final section explores the broader impact of molecular microbiology on value-based care, with discussions on clinical management, laboratory stewardship, and the future of molecular diagnostics in public health. Comprehensive and forward-looking, the Manual of Molecular Microbiology equips readers with both foundational knowledge and practical expertise, making it an indispensable reference for today’s clinical laboratory professionals.
Artificial Intelligence In Healthcare
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Author : Adam Bohr
language : en
Publisher: Academic Press
Release Date : 2020-06-21
Artificial Intelligence In Healthcare written by Adam Bohr and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-21 with Computers categories.
Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. - Highlights different data techniques in healthcare data analysis, including machine learning and data mining - Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks - Includes applications and case studies across all areas of AI in healthcare data
Evolution Of Translational Omics
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-09-13
Evolution Of Translational Omics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Science categories.
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Insights In Systems Microbiology 2021
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Author : George Tsiamis
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-06
Insights In Systems Microbiology 2021 written by George Tsiamis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-06 with Science categories.
Genomic Intelligence
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Author : Sheetanshu Gupta
language : en
Publisher: CRC Press
Release Date : 2024-12-06
Genomic Intelligence written by Sheetanshu Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-06 with Science categories.
The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. The subject matter in this book provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental. Print edition not for sale in South Asia (India, Sri Lanka, Nepal, Bangladesh, Pakistan or Bhutan)
Omics
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Author : Debmalya Barh
language : en
Publisher: CRC Press
Release Date : 2013-03-26
Omics written by Debmalya Barh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-26 with Medical categories.
With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields—including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics—present budding solutions to combat global challenges in biomedicine, agriculture, and the environment. OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences provides valuable insights into the applications of modern omics technologies to real-world problems in the life sciences. Filling a gap in the literature, it offers a broad, multidisciplinary view of current and emerging applications of omics in a single volume. Written by highly experienced active researchers, each chapter describes a particular area of omics and the associated technologies and applications. Topics covered include: Proteomics, epigenomics, and pharmacogenomics Toxicogenomics and the assessment of environmental pollutants Applications of plant metabolomics Nutrigenomics and its therapeutic applications Microalgal omics and omics approaches in biofuel production Next-generation sequencing and omics technology for transgenic plant analysis Omics approaches in crop improvement Engineering dark-operative chlorophyll synthesis Computational regulomics Omics techniques for the analysis of RNA splicing New fields, including metagenomics, glycomics, and miRNA Breast cancer biomarkers for early detection Environomics strategies for environmental sustainability This timely book explores a wide range of omics application areas in the biomedical, agricultural, and environmental sciences. Throughout, it highlights working solutions as well as open problems and future challenges. Demonstrating the diversity of omics, it introduces readers to state-of-the-art developments and trends in omics-driven research.
Molecular Diagnostics Promises And Possibilities
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Author : Mousumi Debnath
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-29
Molecular Diagnostics Promises And Possibilities written by Mousumi Debnath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-29 with Medical categories.
A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.