Application Of Nanoparticles In Brain Tumor Treatment
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Application Of Nanoparticles In Brain Tumor Treatment
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Author : Gerardo Caruso
language : en
Publisher: Momentum Press
Release Date : 2012-08-10
Application Of Nanoparticles In Brain Tumor Treatment written by Gerardo Caruso and has been published by Momentum Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-10 with Technology & Engineering categories.
Despite progress in surgery, radiotherapy, and chemotherapy, an effective treatment of gliomas does not yet exist. This new monograph in the ASME-Momentum Press series on Biomedical & Nanomedical Technologies book shows how nanotechnology could be used both to improve the treatment efficacy and to reduce the adverse side effects. It will explain how nanotechnology-based approaches to targeted delivery of drugs across the brain-blood barrier may potentially be engineered to carry out specific functions as needed.
Nanoparticles And Brain Tumor Treatment
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Author : Gerardo Caruso
language : en
Publisher:
Release Date : 2012
Nanoparticles And Brain Tumor Treatment written by Gerardo Caruso and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Brain categories.
Despite progress in surgery, radiotherapy, and in chemotherapy, an effective curative treatment of gliomas does not yet exist. Mortality is still close to 100% and the average survival of patients with GBM is less than 1 year. The efficacy of current anti-cancer strategies in brain tumors is limited by the lack of specific therapies against malignant cells. Besides, the delivery of the drugs to brain tumors is limited by the presence of the blood brain barrier. The oncogenesis of gliomas is characterized by several biological processes and genetic alterations, involved in the neoplastic transformation. The modulation of gene expression to more levels, such as DNA, mRNA, proteins and transduction signal pathways, may be the most effective modality to down-regulate or silence some specific gene functions. Gliomas are characterized by extensive microvascular proliferation and a higher degree of vasculature. In malignant gliomas targeted therapies efficacy is low. In this complex field, it seems to be very important to improve specific selective drugs delivery systems. Drugs, antisense oligonucleotides, small interference RNAs, engineered monoclonal antibodies and other therapeutic molecules may diffuse into CNS overcoming the BBB. Nanotechnology could be used both to improve the treatment efficacy and to reduce the adverse side effects. Nanotechnology-based approaches to targeted delivery of drugs across the BBB may potentially be engineered to carry out specific functions as needed. Moreover, nanoparticles show tumor-specific targeting and long blood circulation time, with consequent low-short-term toxicity. Nanotechnology deals with structures and devices that are emerging as a new field of research at the interface of science, engineering and medicine. Nanomedicine, the application of nanotechnology to healthcare, holds great promise for revolutionizing medical treatments, imaging, faster diagnosis, drug delivery and tissue regeneration.
Nanoparticles And Brain Tumor Treatment
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Author : Gerardo Caruso
language : en
Publisher: Biomedical & Nanomedical Techn
Release Date : 2012
Nanoparticles And Brain Tumor Treatment written by Gerardo Caruso and has been published by Biomedical & Nanomedical Techn this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
This concise monograph series focuses on the implementation of various engineering principles in the conception, design, development, analysis and operation of biomedical, biotechnological and nanotechnology systems and applications. Authors are encouraged to submit their work in the following core topics, but authors should contact the commissioning editor before submitting a proposal: Biomedical Devices & Materials Trauma Analysis Vibration and Acoustics in Biomedical Applications Innovations in Processing, Characterization and Applications of Bioengineered Materials Viscoelasticity of Biological Tissues and Ultrasound Applications Dynamics, and Control in Biomechanical Systems Clinical Applications of Bioengineering Transport Phenomena In Biomedical Applications Computational Modeling and Device Design Safety and Risk Analysis of Biomedical Engineering Modeling and Processing of Bioinspired Materials and Biomaterials Nanomedical Devices & Materials Bio Nano Materials Nano Medical Sciences Materials for Drug & Gene Delivery Nanotechnology for Central Nervous System Nanomaterials & Living Systems Interactions Biosensing, Diagnostics & Imaging Cancer Nanotechnology Micro & Nano Fluidics Environmental Health & Safety Soft Nanotechnology & Colloids Book jacket.
Nanotechnology Based Targeted Drug Delivery Systems For Brain Tumors
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Author : Prashant Kesharwani
language : en
Publisher: Academic Press
Release Date : 2018-04-20
Nanotechnology Based Targeted Drug Delivery Systems For Brain Tumors written by Prashant Kesharwani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-20 with Medical categories.
Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors
Brain Tumor Targeting Drug Delivery Systems Advanced Nanoscience For Theranostics Applications
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Author : Ram Kumar Sahu
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-09-02
Brain Tumor Targeting Drug Delivery Systems Advanced Nanoscience For Theranostics Applications written by Ram Kumar Sahu and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-02 with Medical categories.
Brain Tumor Targeting Drug Delivery Systems: Advanced Nanoscience for Theranostics Applications is a comprehensive reference focused on the latest advancements in nanotechnology for brain tumor therapy. With practical insights and cutting-edge research, this book equips readers with the knowledge to develop innovative drug delivery systems for effective brain tumor diagnosis and treatment. Structured into insightful chapters, this book covers the anatomy, physiology, and pathophysiology of the brain, addressing barriers to targeted drug delivery strategies. Chapters explore theranostics-based delivery systems, including polymeric nanoparticles, liposomes, dendrimers, nanoemulsions, micelles, and inorganic nanoparticles, for precise brain tumor diagnosis and treatment. This informative resource is designed for students and research scholars in pharmacology, pharmaceutical industry scientists, professors, and clinical medicine researchers. With comprehensive chapters and references for further reading, this book facilitates easy understanding of the intricate nanomedical technology, empowering researchers to make significant strides in the field of brain tumor therapy. Key Features: Structured chapters for easy understanding of nanotechnology concepts In-depth coverage of theranostics-based delivery systems for brain tumor diagnosis and treatment References for further reading and exploring new advances in drug delivery systems
Innovative Brain Tumor Therapy
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Author : Gerardo Caruso
language : en
Publisher: Woodhead Publishing
Release Date : 2014-10-10
Innovative Brain Tumor Therapy written by Gerardo Caruso and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Medical categories.
Despite recent advances, therapeutic efforts have not been successful establishing a definitive strategy of treatment for brain gliomas, because of the presence of the blood-brain barrier. Innovative Brain Tumor Therapy presents a synopsis of the studies on nanoparticles as ideal devices for brain tumor treatment. Their nanometric size, electrostatic charge, and lipophilic characteristics allow them to penetrate into the brain tissue freely. Promising in-vitro results have been reported, but remain to be validated in humans. This title focuses on the blood-brain barrier pathophysiology in brain tumors, and the possibilities of overcoming this with nanoparticle-based systems. Relevant patents of nanoparticles used as drug delivery carriers are also reported, as well as future scenarios in nanoparticles and stem cells.
Nanomedicine For The Treatment Of Disease
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Author : Sarwar Beg
language : en
Publisher: CRC Press
Release Date : 2019-09-25
Nanomedicine For The Treatment Of Disease written by Sarwar Beg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Business & Economics categories.
This new volume, Nanomedicine for the Treatment of Disease: From Concept to Application, looks at the application of nanomedicines with a particular focus on their use in the treatment of diseases. The chapters in this volume, contributed by eminent scientists, researchers, and nanotechnologists from across the globe, highlight key advancements, challenges, and opportunities in the area of application of nanomedicines for disease treatment. They explore the design and development of therapeutic nanocarriers for targeting drugs for satiating the demands of disease treatment process. The volume explores the use nanomedicines for the diagnosis and treatment of a multitude various diseases and health conditions, including respiratory diseases, neurological disorders, genetic diseases, pulmonary fungal infections, neuroAIDS, cardiovascular disorders, gastric and colonic diseases, skin disorders, cancer, brain tumors, leishmaniasis and other visceral diseases, hypertension, and ocular diseases.
Nanotechnology Methods For Neurological Diseases And Brain Tumors
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Author : Yasemin Gürsoy Özdemir
language : en
Publisher: Academic Press
Release Date : 2017-07-14
Nanotechnology Methods For Neurological Diseases And Brain Tumors written by Yasemin Gürsoy Özdemir and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-14 with Medical categories.
Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer’s, Parkinson’s and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors. Comprehensive guide for up-to-date views on the latest advances in targeted treatment strategies for brain tumors and neurological diseases Designed with a multidisciplinary approach that links neurology, neuro-oncology and nanoscience to drug delivery to the brain with an emphasis on the blood-brain-barrier Written in a language that makes it easy to understand nanotechnology drug delivery techniques Presents a unique book that also covers advanced treatment approaches of neurological diseases and brain tumors
Nanomedicine In Brain Diseases
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Author : Xue Xue
language : en
Publisher: Springer Nature
Release Date : 2019-11-07
Nanomedicine In Brain Diseases written by Xue Xue and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-07 with Science categories.
This book provides an overview of the current applications of nanomaterials in brain diseases, and introduces several novel nanomaterials that have excellent potential in this field. During the last two decades, nanotechnology had matured significantly as it has transitioned from a bench-top science to an applied technology. However, the application of nanomaterials in basic and clinical neuroscience is still at an early stage, and understanding how the intrinsic properties of nanomaterials translate to complex biological responses is an area of intensive research. Part 1 of the book focuses on the principles and strategies of nanomedicine in the brain diseases, while part 2 examines the applications of promising nanomaterials for therapy and diagnosis in the brain. Together they offer a comprehensive picture of advances in nanotechnology and their successful use in treating brain diseases in the past 20 years.
Innovative Brain Tumor Therapy
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Author : Gerardo Caruso
language : en
Publisher: Woodhead Publishing
Release Date : 2014-10-10
Innovative Brain Tumor Therapy written by Gerardo Caruso and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Medical categories.
Despite recent advances, therapeutic efforts have not been successful establishing a definitive strategy of treatment for brain gliomas, because of the presence of the blood-brain barrier. Innovative Brain Tumor Therapy presents a synopsis of the studies on nanoparticles as ideal devices for brain tumor treatment. Their nanometric size, electrostatic charge, and lipophilic characteristics allow them to penetrate into the brain tissue freely. Promising in-vitro results have been reported, but remain to be validated in humans. This title focuses on the blood-brain barrier pathophysiology in brain tumors, and the possibilities of overcoming this with nanoparticle-based systems. Relevant patents of nanoparticles used as drug delivery carriers are also reported, as well as future scenarios in nanoparticles and stem cells.