Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence
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Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence State Of The Art And Perspectives
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Author : Simona Francese
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-12-20
Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence State Of The Art And Perspectives written by Simona Francese and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-20 with Law categories.
In this book, developments of LC-MS and GC-MS based techniques are covered with respect to operational practice and new applications, accompanied by other MS-based techniques that are increasing forensic opportunities and that operate on a variety of evidence types.
Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence
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Author : Simona Francese
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-12-20
Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence written by Simona Francese and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-20 with Science categories.
Mass spectrometry is one of the most versatile analytical techniques due to the vast range of analytes that it can detect and quantify and, as such, for its contribution to a significant number of life science fields. The legal and forensics community has certainly benefited from this technique, which has been able to provide reliable evidence in court cases. Liquid Chromatography/Gas Chromatography–Mass Spectrometry (LC/GC–MS) still have a dominant role in the provision of forensic intelligence. However, in the past decade new and exciting MS-based techniques have emerged and are or have evolved to be at an operational deployment maturity, enabling either fast, ambient, non-destructive, or portable screening (or encompass all of these features). In this book, developments of LC–MS and GC–MS based techniques are covered with respect to operational practice and new applications, accompanied by other MS-based techniques that are increasing forensic opportunities and that operate on a variety of evidence types. Whilst the underpinning working principles of each relevant mass spectrometry technique are summarised, each chapter primarily focuses on its implementation in criminal investigation and court cases. In the last chapters, this book additionally covers emerging MS technologies that are at the beginning of their operational implementation journey as well as niche applications outside the fields of traditional forensic science but with a clear potential to impact future investigations (forensics beyond the courtroom). This book provides an up-to-date reference for the mass spectrometry-based tools that are currently available both as established and as emerging methods within forensic practice. It will help casework commissioning managers and forensic providers worldwide to make more informed decisions as to the forensic strategy and workflow when examining exhibits. It is also recommended to postgraduates and early career investigators with reference to the contribution that these techniques and methods could make if applied to classic forensic science practice.
Secondary Ion Mass Spectrometry
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Author : Paweł Piotr Michałowski
language : en
Publisher: Royal Society of Chemistry
Release Date : 2025-06-06
Secondary Ion Mass Spectrometry written by Paweł Piotr Michałowski and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-06 with Science categories.
Secondary ion mass spectrometry (SIMS) is a technique used to analyse the composition of solid surfaces and thin films by sputtering the surface of the specimen with a primary ion beam and collecting and analysing ejected secondary ions. The technique has been applied to quality assurance in semiconductor manufacture, in forensics for enhancement of fingerprints and to determine the composition of cometary dust. This book briefly introduces the fundamentals of the SIMS technique and discusses in detail recent advancements and applications in various branches of science. From an extensive literature review, it provides a good overview of how to reproduce the most prominent experiments and what instruments are required or suited to the analysis. It will inspire new designs and hence research for the future. Appealing to graduates or postgraduates who want an overview of the field and how to use this technique, researchers new to this field will find innovative solutions and how to achieve them detailed herein.
Glycoprotein Analysis
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Author : Weston B Struwe
language : en
Publisher: Royal Society of Chemistry
Release Date : 2024-10-16
Glycoprotein Analysis written by Weston B Struwe and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-16 with Science categories.
Glycoproteins are central to numerous cellular processes and are among the most structurally complex biomolecules in nature. This unique complexity stems from variability in complex oligosaccharides that are located throughout the protein, a feature that is profoundly important for regulating biomolecular interactions but also makes glycoproteins difficult to study. As such, glycoprotein analysis entails a range of techniques to bridge the knowledge gap between glycoprotein structure and biological function. This book serves as an authoritative guide to glycoprotein analysis, written by internationally recognised experts in the field and discussed in the context of real-world applications across the life sciences. It provides a wide-ranging assessment of the modern methods, from those used to characterise glycoprotein structure, to approaches proficient in uncovering the molecular mechanisms by which they function as well as those capable of measuring structural dynamics and macromolecular assembly. These methods differ to a large extent and include mass spectrometry, glycan/lectin arrays, nuclear magnetic resonance, infrared spectroscopy, scanning probe microscopy and high-performance liquid chromatography. Equally important are computational techniques, including molecular dynamics and bioinformatics, which are also covered and discussed in the wider context of glycoprotein analysis. Glycobiology is indeed a rapidly growing field and the development of advanced tools for glycoproteins analysis has been enabled by researchers from different backgrounds working to overcome long-standing analytical challenges and biological questions involving glycosylation. This book is intended to aid academic and professional researchers at various levels of their career to gain a deeper appreciation of cutting-edge methods in glycoprotein analysis and their applications in biomolecular research, biotherapeutic development, structural biology and biophysical chemistry.
Gas Chromatography In Forensic Science
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Author : Ian Tebbett
language : en
Publisher: CRC Press
Release Date : 1992-10-31
Gas Chromatography In Forensic Science written by Ian Tebbett and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-31 with Law categories.
Describes the application of gas chromatography to various aspects of forensic chemistry. Following an introduction to the basic theory of chromatographic separations, the text discusses specific issues, such as drug analysis, fires and explosives, alcohol and toxicology.
Advances In Forensic Human Identification
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Author : Xanthe Mallett
language : en
Publisher: CRC Press
Release Date : 2014-01-24
Advances In Forensic Human Identification written by Xanthe Mallett and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-24 with Law categories.
As forensic human identification receives increased global attention, practitioners, policy makers, and students need an appropriate resource that describes current methods and modalities that have shaped today’s policies and protocols. A supplemental follow-up to Forensic Human Identification: An Introduction, Advances in Forensic Human Identification covers advances in the most well-known scientific techniques and discusses new and developing subjects and modalities of human identification. A collection of contributions from worldwide experts, the book embraces a broad context and looks at several issues beyond physical identification of human remains or offenders. The book examines online, sexual, and biometric identities and discusses problems associated with investigative practice, such as the developing use of the Internet as a distribution and communication medium for criminal activities. It also explores miscarriages of justice that can result from flawed applications or interpretations of forensic evidence. Finally, it looks at the future of forensic science in the United Kingdom in light of financial challenges and the closure of the Forensic Science Service. Where appropriate, case studies illustrate the use of techniques and the associated problems described in the text. A supplemental CD includes images in full color. This volume provides an important contribution to the ongoing practitioner and academic debates surrounding the application of forensic technologies. The insight presented is destined to springboard further inquiry into enhanced techniques and underlies the need for more research into the appropriate use of identification techniques to solve the mysteries of the unknown.
Magnetic Resonance And Its Applications In Drug Formulation And Delivery
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Author : Michael D Mantle
language : en
Publisher: Royal Society of Chemistry
Release Date : 2024-03-27
Magnetic Resonance And Its Applications In Drug Formulation And Delivery written by Michael D Mantle and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-27 with Science categories.
This book details the latest research and development in the use of magnetic resonance imaging and spectroscopy as tools to give quantitative insights concerning late stage pharmaceutical formulation, tablet manufacturing and drug dissolution behaviour. The book combines different facets of magnetic resonance and highlights the use of spatial resolution (MRI) and how this adds to the knowledge base to further our understanding of the microscopic physicochemical processes occurring during drug release from solid dosage forms. New topics, that have not been thoroughly reviewed elsewhere, are covered including the applications of solution state magnetic resonance in process scale up, reaction monitoring/understanding and process analytical technologies (PAT); dissolution testing; and counterfeit analysis. Solid state NMR and its role in understanding phase separation in dispersions, polymorphism and crystallography are included and magnetic resonance imaging and its use in assessing tablet dissolution performance, mass transport and mixing in hot melt extrusion (HME) are covered. Focusing on late stage development rather than molecular drug discovery provides a unique approach and the book will appeal to a diversity of disciplines using spectroscopy for study. Aimed at researchers in drug development, manufacture and formulation in both industry (pharmaceutical companies) and academia (pharmacy program), it includes examples, where appropriate, of studies on commercially available pharmaceutical products.
Mass Spectrometry Handbook
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Author : Mike S. Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-08
Mass Spectrometry Handbook written by Mike S. Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-08 with Science categories.
Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.
Digital Forensics And Internet Of Things
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Author : Anita Gehlot
language : en
Publisher: John Wiley & Sons
Release Date : 2022-04-19
Digital Forensics And Internet Of Things written by Anita Gehlot and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-19 with Computers categories.
DIGITAL FORENSICS AND INTERNET OF THINGS It pays to be ahead of the criminal, and this book helps organizations and people to create a path to achieve this goal. The book discusses applications and challenges professionals encounter in the burgeoning field of IoT forensics. IoT forensics attempts to align its workflow to that of any forensics practice—investigators identify, interpret, preserve, analyze and present any relevant data. As with any investigation, a timeline is constructed, and, with the aid of smart devices providing data, investigators might be able to capture much more specific data points than in a traditional crime. However, collecting this data can often be a challenge, as it frequently doesn’t live on the device itself, but rather in the provider’s cloud platform. If you can get the data off the device, you’ll have to employ one of a variety of methods given the diverse nature of IoT devices hardware, software, and firmware. So, while robust and insightful data is available, acquiring it is no small undertaking. Digital Forensics and Internet of Things encompasses: State-of-the-art research and standards concerning IoT forensics and traditional digital forensics Compares and contrasts IoT forensic techniques with those of traditional digital forensics standards Identifies the driving factors of the slow maturation of IoT forensic standards and possible solutions Applies recommended standards gathered from IoT forensic literature in hands-on experiments to test their effectiveness across multiple IoT devices Provides educated recommendations on developing and establishing IoT forensic standards, research, and areas that merit further study. Audience Researchers and scientists in forensic sciences, computer sciences, electronics engineering, embedded systems, information technology.
Advances In Forensic Applications Of Mass Spectrometry
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Author : Jehuda Yinon
language : en
Publisher: CRC Press
Release Date : 2003-12-29
Advances In Forensic Applications Of Mass Spectrometry written by Jehuda Yinon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-29 with Law categories.
Recent developments in analytical instrumentation have had an enormous influence on forensic analysis. The mass spectrometer is now an integral part of every forensic laboratory, resulting in greater analytical accuracy, more reliable identification, and lower detection limits. As the instrumental method of choice among forensic analysts, the mass