Applications Of Mass Spectrometry In Life Safety
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Applications Of Mass Spectrometry In Life Safety
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Author : Crisan Popescu
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-02
Applications Of Mass Spectrometry In Life Safety written by Crisan Popescu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-02 with Science categories.
Mass spectrometry (MS) along with its hyphenated techniques is capable of high throughput, sensitivity, accuracy and selectivity for the analysis of structure and composition of almost any product. Like in electrophoresis, MS separates mo- cules based on the mass-to-charge ratio. In case of gel electrophoresis (SDS- PAGE), a well-known and efficient bioanalytical technique, proteins bear negative charges but have the same charge density, so proteins are separated according to their size. Similarly, in case of MS analysis, proteins carry the same charge, and are separated by their molecular weight. Unlike SDS-PAGE, however, modern ultra high resolution MS discerns very small mass differences and can resolve and completely identify in a single experiment species of the same nominal mass in complex biological mixtures. Consequently, MS can be used for the structural characterization, identification and sensitive detection of mixtures of biomolecules or for assessing the quality of isolated proteins (purity, integrity, or post-translational modifications, for example), carbohydrates, nucleic acids, drugs, metabolites, pollutants etc. In the post-genome era, MS is continuously developing as one of the most re- able analytical method for elucidating the structure of molecules originating from various biological matrices. The potential of MS for high-sensitive structural a- lyses became unsurpassable after the introduction of electrospray (ESI) and matrix assisted laser/desorption ionization (MALDI) methods, on one hand, and the pos- bility to deduce in detail unknown biopolymer structures by highly accurate mo- cular mass measurement followed by sequencing using dissociation techniques based on multiple stage MS, on the other.
Advancements Of Mass Spectrometry In Biomedical Research
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Author : Alisa G. Woods
language : en
Publisher: Springer
Release Date : 2014-06-20
Advancements Of Mass Spectrometry In Biomedical Research written by Alisa G. Woods and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-20 with Science categories.
This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.
Medical Applications Of Mass Spectrometry
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Author : Karoly Vekey
language : en
Publisher: Elsevier
Release Date : 2011-08-11
Medical Applications Of Mass Spectrometry written by Karoly Vekey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-11 with Science categories.
Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.
Forensic Science
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Author : Evgeny Katz
language : en
Publisher: John Wiley & Sons
Release Date : 2016-06-27
Forensic Science written by Evgeny Katz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-27 with Medical categories.
Concentrating on the natural science aspects of forensics, top international authors from renowned universities, institutes, and laboratories impart the latest information from the field. In doing so they provide the background needed to understand the state of the art in forensic science with a focus on biological, chemical, biochemical, and physical methods. The broad subject coverage includes spectroscopic analysis techniques in various wavelength regimes, gas chromatography, mass spectrometry, electrochemical detection approaches, and imaging techniques, as well as advanced biochemical, DNA-based identification methods. The result is a unique collection of hard-to-get data that is otherwise only found scattered throughout the literature.
Forensic Applications Of Mass Spectrometry
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Author : Jehuda Yinon
language : en
Publisher: CRC Press
Release Date : 2020-11-25
Forensic Applications Of Mass Spectrometry written by Jehuda Yinon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Law categories.
Forensic Applications of Mass Spectrometry combines the most current developments in applications of mass spectrometry techniques to forensic analyses. The techniques discussed include: capillary-GC/MS thermospray-LC/MS tandem mass spectrometry (MS/MS) pyrolysis-GC/MS isotope ratio mass spectrometry The applications include: analysis of body fluids and hair for drugs of abuse drug testing in sports analysis of accelerants in fire debris detection of hidden explosives in luggage and mail identification of explosives in post-explosion debris examination of evidential materials (paints, fibers, synthetic polymers) authentication of regulated products (flavoring substances, fruit juices) protection of industrial products by isotopic signature
Mass Spectrometry
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Author : Edmond de Hoffmann
language : en
Publisher: Wiley
Release Date : 2001-10-10
Mass Spectrometry written by Edmond de Hoffmann and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-10 with Science categories.
Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI
Conservation Science
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Author : Paul Garside
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-12-03
Conservation Science written by Paul Garside and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-03 with Science categories.
Conservation techniques for the analysis and preservation of heritage materials are constantly progressing. Building on the first edition of Conservation Science, this new edition incorporates analytical techniques and data processing methods that have emerged in the past decade and presents them alongside notable case studies for each class of material. An introductory chapter on analytical techniques provides a succinct overview to bring the reader up-to-speed with which type of material each technique is suitable for, the differing sampling techniques that can be employed, and the handling and processing of the resultant data. Subsequent chapters go on to cover all common heritage materials in turn, from natural substances such as wood and stone to modern plastics, detailing the up-to-date techniques for their analysis. With contributions by scientists working in the museum and heritage sector, this textbook will interest students, scientists involved in conservation, and conservators who want to develop their understanding of their collections at a material level.
Gas Chromatography Mass Spectrometry
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Author : Diane C Turner
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-11-28
Gas Chromatography Mass Spectrometry written by Diane C Turner and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-28 with Science categories.
Gas chromatography–mass spectrometry (GC-MS) is a powerful way to analyse a range of substances. It is used in everything from food safety to medicine. It has even been used to protect endangered vultures through analysis of poisonous pesticide molecules in their environment! I want to apply this technique, where do I begin? Is GC-MS is the right technique to use? How do I prepare my samples and calibrate the instruments? This textbook has the answers to all these questions and more. Throughout the book, case studies illustrate the practical process, the techniques used and any common challenges. Newcomers can easily search for answers to their question and find clear advice with coloured images on how to get started and all subsequent steps involved in using GC-MS as part of a research process. Readers will find information on collecting and preparing samples, designing and validating methods, analysing results, and troubleshooting. Examples of pollutant, food, oil and fragrance analysis bring the theory to life. The authors use their extensive experience teaching GC-MS theory and practice and draw on their combined backgrounds applying the technique in academic and industry settings to bring this practical reference together. The authors also design and teach the Royal Society of Chemistry’s Pan Africa Chemistry Network GC-MS course, which is supported by GSK.
Mass Spectrometry
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Author : India. Department of Atomic Energy. Bhabha Atomic Research Centre
language : en
Publisher:
Release Date :
Mass Spectrometry written by India. Department of Atomic Energy. Bhabha Atomic Research Centre and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Mass Spectrometry Mass Spectrometry
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Author : Kenneth L. Busch
language : en
Publisher:
Release Date : 1988
Mass Spectrometry Mass Spectrometry written by Kenneth L. Busch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Mass spectrometry categories.