Applied Pharmacokinetics Pharmacodynamics
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Applied Pharmacokinetics Pharmacodynamics
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Author : Michael E. Burton
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2006
Applied Pharmacokinetics Pharmacodynamics written by Michael E. Burton and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy. This edition includes case studies that apply concepts to actual patient problems. New chapters cover tacrolimus, mycophenolic acid, sirolimus, antipsychotics, and critical evaluation of therapeutic drug monitoring methods. Other new features include more drawings and reference tables and an appendix on outcome studies with therapeutic drug monitoring.
Applied Pharmacokinetics
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Author : William E. Evans
language : en
Publisher: Applied Therapeutics, Incorporated
Release Date : 1992
Applied Pharmacokinetics written by William E. Evans and has been published by Applied Therapeutics, Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Chemotherapy categories.
The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition, and six new chapters have been added on pharmacodynamics, pharmacogenetics, pharmacokinetic considerations in the obese, dietary influences on drug disposition, zidovudine, and corticosteroids. Each chapter is tightly focused on the most important concepts and issues. Chapters on specific drugs are organized in a consistent format for quick, easy information retrieval. Major subheadings include Clinical Pharmacokinetics, Pharmacodynamics, Clinical Application of Pharmacokinetic Data, Analytical Methods, and Prospectus.
Applied Clinical Pharmacokinetics And Pharmacodynamics Of Psychopharmacological Agents
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Author : Michael W. Jann
language : en
Publisher: Springer
Release Date : 2016-03-02
Applied Clinical Pharmacokinetics And Pharmacodynamics Of Psychopharmacological Agents written by Michael W. Jann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-02 with Medical categories.
This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions.Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result. The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.
Applied Clinical Pharmacokinetics 3 E
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Author : Larry A. Bauer
language : en
Publisher: McGraw Hill Professional
Release Date : 2014-01-05
Applied Clinical Pharmacokinetics 3 E written by Larry A. Bauer and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-05 with Medical categories.
The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems throughout the chapter, with a ton of practice problems at the end. Answers for the practice problems are in the back, but not detailed like the sample problems) *Changes in the 3/e includes: *All chapters updated and revised, as needed, including critical new references *Antibiotic individualization and monitoring sections increases use of pharmacodynamic parameters (Cmax/MIC, AUC24/MIC, Time above MIC) in addition to pharmacokinetic parameters to adjust dosages *Anticonvulsants section includes 5 new agents (Fosphenytoin, Lamotrigine, Levetiracetam, Oxcarbazepine, Eslicarbazepine) *Immunosuppressants section includes 1 new agent (Sirolimus), About the Book Text focuses on the latest standardized techniques and approaches to patient-specific dosing and provides up-to-date information on more recently moniotored drugs. Features Clear, useful coverage of drug dosing and drug monitoring Clear and concise summary of pharmacokinetic and pharmacodynamic concepts Practical help with calculations and equations Focus on the latest standardized techniques and approaches to patient-specific dosing Up-to-date information on more recently monitored drugs Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure All the information practitioners need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Full coverage of drugs such as Aminoglycosides, Vancomycin, Digoxin, Phenytoin, Carbamazepine, Theophylline, Cyclosporine, Tacrolimus, and Lithium Student friendly approach to teaching pharmacokinetics--sample problems embedded into the text to allow for students to apply what they are learing. .
Applied Biopharmaceutics Pharmacokinetics Fifth Edition
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Author : Leon Shargel
language : en
Publisher: McGraw Hill Professional
Release Date : 2004-08-19
Applied Biopharmaceutics Pharmacokinetics Fifth Edition written by Leon Shargel and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-19 with Medical categories.
The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
Applied Biopharmaceutics Pharmacokinetics
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Author : Leon Shargel
language : en
Publisher: McGraw-Hill/Appleton & Lange
Release Date : 1999
Applied Biopharmaceutics Pharmacokinetics written by Leon Shargel and has been published by McGraw-Hill/Appleton & Lange this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
This work emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, pharmacodynamics, metabolism and drug delivery.
Applied Biopharmaceutics Pharmacokinetics Sixth Edition
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Author : Leon Shargel
language : en
Publisher: McGraw Hill Professional
Release Date : 2012-04-11
Applied Biopharmaceutics Pharmacokinetics Sixth Edition written by Leon Shargel and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-11 with Medical categories.
A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.
Shargel And Yu S Applied Biopharmaceutics Pharmacokinetics 8th Edition
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Author : Leon Shargel
language : en
Publisher: McGraw Hill Professional
Release Date : 2022-01-24
Shargel And Yu S Applied Biopharmaceutics Pharmacokinetics 8th Edition written by Leon Shargel and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Medical categories.
The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts. Features: Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development Additional chapters for this edition include: o Physiological factors related to drug absorption o Approaches to pharmacokinetics and pharmacodynamics calculations o Novel and complex dosage Forms o Clinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products o Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development Additional information on drug therapy, drug product performance, and other related topics Frequently asked questions, practice problems, clinical examples and learning questions
Applied Biopharmaceutics And Pharmacokinetics
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Author : Leon Shargel
language : en
Publisher: McGraw-Hill/Appleton & Lange
Release Date : 1993
Applied Biopharmaceutics And Pharmacokinetics written by Leon Shargel and has been published by McGraw-Hill/Appleton & Lange this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.
Applied Biopharmaceutics Pharmacokinetics Seventh Edition
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Author : Leon Shargel
language : en
Publisher: McGraw Hill Professional
Release Date : 2015-11-22
Applied Biopharmaceutics Pharmacokinetics Seventh Edition written by Leon Shargel and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-22 with Medical categories.
The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics—now fully updated. Explains how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Helps you critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Chapters have been revised to reflect the latest clinical perspectives on drug performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field’s leading text for more than three decades, Applied Biopharmaceutics & Pharmacokinetics gets you up to speed on the basics of the discipline like no other resource. Practical problems and clinical examples with discussions are integrated within each chapter to help you apply principles to patient care and drug consultation situations. In addition, outstanding pedagogy, including chapter objectives, chapter summaries, and FAQs, plus additional application questions, identify and focus on key concepts. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics shows you how to use raw data and formulate the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination. The book also helps you work with pharmacokinetic and biopharmaceutic parameters to design and evaluate dosage regimens of drugs. In the seventh edition of this must-have interactive learning tool, most of the chapters are updated to reflect our current understanding of complex issues associated with safe and efficacious drug therapy.