Arteriogenesis
DOWNLOAD
AUDIOBOOK
Download Arteriogenesis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Arteriogenesis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Arteriogenesis
DOWNLOAD
AUDIOBOOK
Author : Wolfgang Schaper
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Arteriogenesis written by Wolfgang Schaper and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
Emphasizes the research activities of Germany’s Nauheim Institute of the Max Planck Society and its group of investigators both past and present, in the field of collateral artery growth. Incorporates a multidisciplinary in vivo approach to the study of arteriogenesis that includes molecular approaches with classical physiology and immunohistochemistry. Full color throughout and well illustrated.
Arteriogenesis And Therapeutic Neovascularization
DOWNLOAD
AUDIOBOOK
Author : Elisabeth Deindl
language : en
Publisher: MDPI
Release Date : 2020-11-04
Arteriogenesis And Therapeutic Neovascularization written by Elisabeth Deindl and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-04 with Medical categories.
For many years, arteriogenesis, also called collateral formation, has been regarded as being a beneficial process to restore blood flow to distal tissues in occluded arteries. Therefore, it is frequently referred to in relation to therapeutic angiogenesis. Despite the big clinical potential and the many promising clinical trials on arteriogenesis and therapeutic angiogenesis, the exact molecular mechanisms involved in the multifactorial processes of arteriogenesis are still not completely understood. A better understanding is needed in order to define successful clinical therapies. In this Special Issue, multiple aspects of arteriogenesis and therapeutic angiogenesis will be addressed, ranging from the role of inflammatory processes and immune cells, to growth factors, microRNAs and environmental factors like hypoxia. Therapeutic angiogenesis will also be discussed in relation to the atherosclerosis and intraplaque angiogenesis in hypoxic lesions, as well as specific forms of arteriogenesis in relation to spinal cord blood supply and aorta surgery. The effects of exercise, a frequently prescribed therapy for PAD patients, on arteriogenesis are also discussed. Overall, the papers in this Special Issue on arteriogenesis and therapeutic angiogenesis provide important new insights in the underlying pathophysiological mechanism of these complex processes and may be helpful to define a successful future intervention directed at therapeutic angiogenesis.
Arteriogenesis
DOWNLOAD
AUDIOBOOK
Author : Elisabeth Deindl
language : en
Publisher: MDPI
Release Date : 2020-12-15
Arteriogenesis written by Elisabeth Deindl and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-15 with Science categories.
Cardiovascular occlusive diseases, such as myocardial infarction or stroke, are still the major cause of morbidity and mortality worldwide and are, particularly during the SARS-CoV-2 pandemic, drastically increasing. Arteriogenesis, which describes the process of natural arterial bypass growth, is a tissue- and life-saving process, which is given to us by mother nature to compensate for the function of a stenosed coronary or peripheral artery non-invasively. Since our first investigations on the mechanisms of collateral artery growth, more than 20 years ago, a lot of progress has been made, which we aim to make accessible in the current book. We present the available animal models and share information on the used state of the art techniques. We describe how fluid shear stress, the trigger for arteriogenesis, is translated into biochemical signal transduction cascades, and we also highlight the functional role of extracellular RNA and Il10. We address the problematic features of arteriogenesis in patients suffering from diabetes mellitus, and provide an overview of currently available or potentially therapeutic approaches to promote arteriogenesis in patients. We focus on the combination of ultrasound and microbubbles, the permanent occlusion of the internal mammary arteries, and simple exercise training. We believe that we have come much closer to achieving our goal of understanding the mechanisms of arteriogenesis, enabling clinicians to promote collateral artery growth in patients and cure vascular occlusive diseases.
Arteriogenesis Prognosis And Therapeutical Potential
DOWNLOAD
AUDIOBOOK
Author : Darius Henatsch
language : en
Publisher: GRIN Verlag
Release Date : 2009-09-18
Arteriogenesis Prognosis And Therapeutical Potential written by Darius Henatsch and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Medical categories.
Essay from the year 2008 in the subject Medicine - Internal Medicine, grade: Excellent , Maastricht University, course: Cardiology and Vascular Medicine , language: English, abstract: Due to the fast growing field of molecular cardiology, mechanisms responsible for collateral artery growth (arteriogenesis) are widely unravelled. After coronary artery occlusion, flow shear stress induces endothelial cell expression and release of adhesion molecules and chemokines. Monocytes are attracted and transmigrate into the vessel wall to release pro-arteriogenic molecules. The process of collateral vessel growth is severely impaired in patients with different risk factors for atherosclerosis, as diabetes or hyperlipedemia. This can be attributed to the impaired migration capacity of monocytes towards pro-arteriogenic stimuli, like MCP-1 and VEGF-A. In these patients “at risk”, blood derived monocytes offer a possibility to predict the individual ability to form functional collaterals by an in vitro performed migration assay. Furthermore, growth factor therapy can be used to enhance and restore collateral growth in patients with impaired arteriogenesis. Here, the migration assay could perfectly be used to for individual adjustment of therapeutical interventions.
Arteriogenesis And Therapeutic Neovascularization
DOWNLOAD
AUDIOBOOK
Author : Elisabeth Deindl
language : en
Publisher:
Release Date : 2020
Arteriogenesis And Therapeutic Neovascularization written by Elisabeth Deindl and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
For many years, arteriogenesis, also called collateral formation, has been regarded as being a beneficial process to restore blood flow to distal tissues in occluded arteries. Therefore, it is frequently referred to in relation to therapeutic angiogenesis. Despite the big clinical potential and the many promising clinical trials on arteriogenesis and therapeutic angiogenesis, the exact molecular mechanisms involved in the multifactorial processes of arteriogenesis are still not completely understood. A better understanding is needed in order to define successful clinical therapies. In this Special Issue, multiple aspects of arteriogenesis and therapeutic angiogenesis will be addressed, ranging from the role of inflammatory processes and immune cells, to growth factors, microRNAs and environmental factors like hypoxia. Therapeutic angiogenesis will also be discussed in relation to the atherosclerosis and intraplaque angiogenesis in hypoxic lesions, as well as specific forms of arteriogenesis in relation to spinal cord blood supply and aorta surgery. The effects of exercise, a frequently prescribed therapy for PAD patients, on arteriogenesis are also discussed. Overall, the papers in this Special Issue on arteriogenesis and therapeutic angiogenesis provide important new insights in the underlying pathophysiological mechanism of these complex processes and may be helpful to define a successful future intervention directed at therapeutic angiogenesis.
Arteriogenesis And Therapeutic Angiogenesis
DOWNLOAD
AUDIOBOOK
Author : Paul Quax
language : en
Publisher:
Release Date : 2022
Arteriogenesis And Therapeutic Angiogenesis written by Paul Quax and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Although advances in therapeutic interventions improved outcomes, vascular occlusive diseases are still challenging not only afflicted but also attending physicians, requiring novel therapeutic strategies. Arteriogenesis, sometimes also called therapeutic angiogenesis, refers to the body's own capacity to create a natural bypass around a narrowing or occluded arterial vessel. This book gives an insight into current knowledge and advances in vascular sciences and future prospects of therapeutic options. The utility and relevance of circulating biomarkers together with the potential of machine learning methods are discussed as well as the challenges and prospects of novel therapies such as protein- gene-, and stem cell therapy along with multicistronic multigene vectors and the use of microRNAs, exosomes, and secretomes. Vascular smooth muscle phenotype switch as a target to promote arteriogenesis is critically addressed, highlighting the problem of promoting atherosclerosis in parallel. Two articles even deal with cold-inducible RNA-binding protein CIRP/CIRPB presenting it as promising target to promote vascularization concomitant the reduction in ischemic tissue damage. BMPR kinase inhibition is introduced to improve tissue repair in a hereditary form of vascular disorder, and the role of the AP-1 transcription factor JunB in blood vessel formation is described. Some more experimental oriented articles deal with the relevance of choosing the appropriate mouse strain for investigations as well as in vitro Matrigel plug assay as a potent method to investigate angiogenesis. Last but not least, two-photon intravital microscopy is presented as suitable tool to assess plaque angiogenesis in atherosclerotic lesions.
Arteriogenesis And Therapeutic Angiogenesis
DOWNLOAD
AUDIOBOOK
Author : Paul Quax
language : en
Publisher: Mdpi AG
Release Date : 2022-01-13
Arteriogenesis And Therapeutic Angiogenesis written by Paul Quax and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-13 with Medical categories.
Although advances in therapeutic interventions improved outcomes, vascular occlusive diseases are still challenging not only afflicted but also attending physicians, requiring novel therapeutic strategies. Arteriogenesis, sometimes also called therapeutic angiogenesis, refers to the body's own capacity to create a natural bypass around a narrowing or occluded arterial vessel. This book gives an insight into current knowledge and advances in vascular sciences and future prospects of therapeutic options. The utility and relevance of circulating biomarkers together with the potential of machine learning methods are discussed as well as the challenges and prospects of novel therapies such as protein- gene-, and stem cell therapy along with multicistronic multigene vectors and the use of microRNAs, exosomes, and secretomes. Vascular smooth muscle phenotype switch as a target to promote arteriogenesis is critically addressed, highlighting the problem of promoting atherosclerosis in parallel. Two articles even deal with cold-inducible RNA-binding protein CIRP/CIRPB presenting it as promising target to promote vascularization concomitant the reduction in ischemic tissue damage. BMPR kinase inhibition is introduced to improve tissue repair in a hereditary form of vascular disorder, and the role of the AP-1 transcription factor JunB in blood vessel formation is described. Some more experimental oriented articles deal with the relevance of choosing the appropriate mouse strain for investigations as well as in vitro Matrigel plug assay as a potent method to investigate angiogenesis. Last but not least, two-photon intravital microscopy is presented as suitable tool to assess plaque angiogenesis in atherosclerotic lesions.
Arteriogenesis
DOWNLOAD
AUDIOBOOK
Author : Elisabeth Deindl
language : en
Publisher:
Release Date : 2020
Arteriogenesis written by Elisabeth Deindl and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Cardiovascular occlusive diseases, such as myocardial infarction or stroke, are still the major cause of morbidity and mortality worldwide and are, particularly during the SARS-CoV-2 pandemic, drastically increasing. Arteriogenesis, which describes the process of natural arterial bypass growth, is a tissue- and life-saving process, which is given to us by mother nature to compensate for the function of a stenosed coronary or peripheral artery non-invasively. Since our first investigations on the mechanisms of collateral artery growth, more than 20 years ago, a lot of progress has been made, which we aim to make accessible in the current book. We present the available animal models and share information on the used state of the art techniques. We describe how fluid shear stress, the trigger for arteriogenesis, is translated into biochemical signal transduction cascades, and we also highlight the functional role of extracellular RNA and Il10. We address the problematic features of arteriogenesis in patients suffering from diabetes mellitus, and provide an overview of currently available or potentially therapeutic approaches to promote arteriogenesis in patients. We focus on the combination of ultrasound and microbubbles, the permanent occlusion of the internal mammary arteries, and simple exercise training. We believe that we have come much closer to achieving our goal of understanding the mechanisms of arteriogenesis, enabling clinicians to promote collateral artery growth in patients and cure vascular occlusive diseases.
A Clinician S Guide To Arteriogenesis
DOWNLOAD
AUDIOBOOK
Author : Taryn Solomon
language : en
Publisher: Hayle Medical
Release Date : 2023-09-19
A Clinician S Guide To Arteriogenesis written by Taryn Solomon and has been published by Hayle Medical this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.
Arteriogenesis is the increase in the diameter of arterial vessels. The process of development of arteries is supplemented by the migration of pericytes and smooth muscle cells (SMCs) from the epicardium. Majority of the SMCs of the coronary artery stem from the epicardium, however, SMCs of proximal coronary arteries originate from the neural chest. In terms of mechanical simulation, arteriogenesis is associated with elevated pressure which intensifies the stress on the radial wall, and elevates the flow which then intensifies the stress on endothelial surface. The diameter is increased by the vessel until the normalization of the stress. In terms of chemical simulation arteriogenesis is associated with upregulation of cell adhesion and cytokines receptors. The book aims to shed light on some of the unexplored aspects of arteriogenesis and the recent researches in this area of study. It will serve as a reference to a broad spectrum of readers.
Arteriogenesis Molecular Regulation Pathophysiology And Therapeutics I
DOWNLOAD
AUDIOBOOK
Author : Elisabeth Deindl
language : en
Publisher:
Release Date : 2011
Arteriogenesis Molecular Regulation Pathophysiology And Therapeutics I written by Elisabeth Deindl and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.