Assay Development
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A Practical Guide To Assay Development And High Throughput Screening In Drug Discovery
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Author : Taosheng Chen
language : en
Publisher: CRC Press
Release Date : 2009-12-21
A Practical Guide To Assay Development And High Throughput Screening In Drug Discovery written by Taosheng Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-21 with Medical categories.
The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. A P
Assay Development
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Author : Ge Wu
language : en
Publisher: John Wiley & Sons
Release Date : 2010-06-25
Assay Development written by Ge Wu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-25 with Science categories.
Essential principles and practice of assay development The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting. Rather than attempting comprehensive coverage of all assay development technologies, the book introduces the most widely used assay development technologies and illustrates the art of assay development through a few commonly encountered biological targets in assay development (e.g., proteases, kinases, ion channels, and G protein-coupled receptors). Just enough biological background for these biological targets is provided so that the reader can follow the logics of assay development. Chapters discuss: The basics of assay development, including foundational concepts and applications Commonly used instrumental methods for both biochemical assays and cell-based assays Assay strategies for protein binding and enzymatic activity Cell-based assays High-throughput screening An in-depth study of the now popular Caliper's off-chip kinase assay provides an instructive, real-world example of the assay development process.
Assay Development And Evaluation
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Author : Jan S. Krouwer
language : en
Publisher: Amer. Assoc. for Clinical Chemistry
Release Date : 2002
Assay Development And Evaluation written by Jan S. Krouwer and has been published by Amer. Assoc. for Clinical Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Mathematics categories.
Handbook Of Assay Development In Drug Discovery
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Author : Lisa K. Minor
language : en
Publisher: CRC Press
Release Date : 2006-01-20
Handbook Of Assay Development In Drug Discovery written by Lisa K. Minor and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-20 with Medical categories.
The Handbook of Assay Development in Drug Discovery describes all the tools currently available for performing various assay techniques. Featuring troubleshooting advice for common problems from experienced assay developers, the vendor community, and scientists in the pharmaceutical industry, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. Designed as a guide to running an assay from start to finish, this is an ideal bench top companion for scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation.
Firefly Luciferase Atp Assay Development For Monitoring Bacterial Concentrations In Water Supplies
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Author :
language : en
Publisher:
Release Date : 1981
Firefly Luciferase Atp Assay Development For Monitoring Bacterial Concentrations In Water Supplies written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Adenosine triphosphate categories.
Pet
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Author : Michael E. Phelps
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-05-11
Pet written by Michael E. Phelps and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-11 with Medical categories.
This book is a comprehensive guide to PET and PET CT and serves as a valuable resource for practicing physicians and residents. The text covers topics ranging from the basic principles of physics, molecular assays, preparation of molecular imaging probes, and biochemistry relevant for PET. Additionally, clinical applications in cancer, cardiovascular diseases, and neurological disorders are thoroughly discussed. U.C.L.A. School of Medicine is recognized as one of the leading PET centers in the world. All of the contributors are U.C.L.A. School of Medicine faculty members and they combined their areas of expertise in order to create the premier reference book on PET. Each chapter provides a complete overview of the topic material and guides the reader through the subject matter. Figures, tables, and solved example problems are integrated into the text. Readers also benefit from the extensive references and suggested reading material.
Molecular Biomethods Handbook
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Author : John M. Walker
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-04
Molecular Biomethods Handbook written by John M. Walker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-04 with Medical categories.
Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up to date collection of methods used regularly in the authors’ own research programs. This book will prove to be an invaluable reference for those engaged in or entering the field of molecular biology, and will provide the necessary background for those interested in setting up and using the latest molecular techniques.
Burger S Medicinal Chemistry Drug Discovery And Development 8 Volume Set
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Author :
language : en
Publisher: John Wiley & Sons
Release Date : 2021-04-20
Burger S Medicinal Chemistry Drug Discovery And Development 8 Volume Set written by and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-20 with Science categories.
Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.
The Immunoassay Handbook
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Author : David Wild
language : en
Publisher: Elsevier
Release Date : 2005-06-20
The Immunoassay Handbook written by David Wild and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-20 with Medical categories.
Containing updated and new information on advanced technology - including micro and nanoscale immunoassays - this text provides a mix of practical information coupled with a review of clincal applications and practical examples.
Therapeutic Antibodies
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Author : Yuti Chernajovsky
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-11
Therapeutic Antibodies written by Yuti Chernajovsky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-11 with Medical categories.
Antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions and are becoming the molecules of choice for further combination therapies and cell engineering. Current developments and clinical successes are summarised by experts in the drug development field. A must read for immunologists, clinical scientists and novel drug developers.