Assessment Of Osteoporotic Fractures And Risk Prediction
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Assessment Of Osteoporotic Fractures And Risk Prediction
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Author : Zhi-Feng Sheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-30
Assessment Of Osteoporotic Fractures And Risk Prediction written by Zhi-Feng Sheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-30 with Medical categories.
Assessment Of Osteoporotic Fractures And Risk Prediction Volume Ii
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Author : Zhi-Feng Sheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-02
Assessment Of Osteoporotic Fractures And Risk Prediction Volume Ii written by Zhi-Feng Sheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-02 with Medical categories.
Osteoporosis
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Author :
language : en
Publisher:
Release Date : 2012
Osteoporosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
There are a number of therapies and treatments available for the prevention of fragility fractures in people thought to be at risk, or to prevent further fractures in those who have already had one or more fragility fractures. However, identifying who will benefit from preventative treatment is imprecise. A number of risk assessment tools are available to predict fracture incidence over a period of time, and these may be used to aid decision making. These tools are limited in that they may not include all risk factors, or may lack details of some risk factors. Tools are dependent on the accuracy of the epidemiological data used to derive them and tools validated in other populations may not apply to the UK. Two tools, FRAX and QFracture, are available for use in the UK. It is not clear whether these tools are equally accurate and whether choice of tool should depend on circumstances. This short clinical guideline aims to provide guidance on the selection and use of risk assessment tools in the care of people who may be at risk of fragility fractures in all settings in which NHS care is received.
Orthogeriatrics
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Author : Paolo Falaschi
language : en
Publisher: Springer Nature
Release Date : 2021
Orthogeriatrics written by Paolo Falaschi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Anesthesiology categories.
This new open access edition supported by the Fragility Fracture Network aims at giving the widest possible dissemination on fragility fracture (especially hip fracture) management and notably in countries where this expertise is sorely needed. It has been extensively revised and updated by the experts of this network to provide a unique and reliable content in one single volume. Throughout the book, attention is given to the difficult question of how to provide best practice in countries where the discipline of geriatric medicine is not well established and resources for secondary prevention are scarce. The revised and updated chapters on the epidemiology of hip fractures, osteoporosis, sarcopenia, surgery, anaesthesia, medical management of frailty, peri-operative complications, rehabilitation and nursing are supplemented by six new chapters. These include an overview of the multidisciplinary approach to fragility fractures and new contributions on pre-hospital care, treatment in the emergency room, falls prevention, nutrition and systems for audit. The reader will have an exhaustive overview and will gain essential, practical knowledge on how best to manage fractures in elderly patients and how to develop clinical systems that do so reliably.
Guidelines For Preclinical Evaluation And Clinical Trials In Osteoporosis
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Author : World Health Organization
language : en
Publisher:
Release Date : 1998-01-01
Guidelines For Preclinical Evaluation And Clinical Trials In Osteoporosis written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-01-01 with Medical categories.
This book provides comprehensive guidelines for the design, implementation, and interpretation of preclinical studies and clinical trials of agents undergoing investigation for the management of osteoporosis. Noting the magnitude of the public health problem caused by osteoporosis and related fractures, the book responds to the urgent need for a cohesive and rational approach to the search for new therapeutic or preventive agents. Recommended principles and methods reflect the consensus reached by a large number of international experts, representatives of the pharmaceutical industry, and drug regulatory authorities. The book opens with a brief discussion of the current and future public health problem caused by osteoporotic fractures, followed by conceptual and operational definitions of osteoporosis and a recommended classification of four intervention categories that facilitate the definition of treatment objectives and the design of targetted studies. Against this background, the next chapter offers a detailed guide to the aims, design, conduct and interpretation of preclinical studies. Specific recommendations are given for the selection of in vitro and animal models, the design of the study, including dose ranges and duration of treatment, and the most appropriate end-points for assessing efficacy. The most extensive chapter provides a comprehensive description of basic principles and methods to follow during clinical trials. Information ranges from a discussion of problems with the use of bone mineral density to predict fracture risk, through advice on the choice of tests and techniques for measuring the effects of interventions, to a discussion of general principles of trial design, including selection of study population, treatment regimen, duration of studies, sample size, and frequency of measurement. Drawing on these detailed principles and methods, subsequent chapters offer concise guidance specific to phase I and phase II studies, phase III studies in severe osteoporosis, phase III studies in osteoporosis without fragility fractures, and phase III studies in osteopenia. The book concludes with chapters outlining principles and methods for phase III clinical trials in subjects with normal bone mass, and for phase IV studies.
Handbook Of Osteoporosis
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Author : David Reid
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-10-22
Handbook Of Osteoporosis written by David Reid and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-22 with Medical categories.
Written by a world-recognised expert in the field of osteoporosis, who has published extensively, and is recognized as a key opinion leader. Aimed at primary care physicians, rheumatologists, orthopaedic surgeons, geriatricians, endocrinologists, and nurse specialists who wish to keep up to date in the prevention and management of osteoporosis High quality clinical photos and figures to enhance descriptions and aid diagnosis Written by a well-known author During the menopause, both the quantity and quality of bone decline rapidly, leading to a dramatic increase in the risk of fracture in postmenopausal women. Although many factors are known to be associated with osteoporotic fractures, measures to identify and treat women at risk are underused in clinical practice. Consequently, osteoporosis is frequently not detected until a fracture occurs. Identification of postmenopausal women at high risk of fracture therefore is a priority. The Handbook of Osteoporosis reviews the risk factors, and lifestyle changes that can help prevent osteoporosis and evaluates the pharmacological treatments currently available.
Prevention And Treatment Of Osteoporosis In The High Risk Patient
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Author : Cyrus Cooper
language : en
Publisher: CRC Press
Release Date : 2005-01-25
Prevention And Treatment Of Osteoporosis In The High Risk Patient written by Cyrus Cooper and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-25 with Medical categories.
The outcome of recent clinical trials in osteoporosis was the impetus for this volume. In these studies of two bisphosphonates, an interaction between bone mineral density (BMD) and the treatment effect was seen, such that these agents appeared to lose their effect as BMD increased. To practitioners this is counter-intuitive. Why should treatment w
The Duration And Safety Of Osteoporosis Treatment
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Author : Stuart Silverman
language : en
Publisher: Springer
Release Date : 2015-12-29
The Duration And Safety Of Osteoporosis Treatment written by Stuart Silverman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-29 with Medical categories.
Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.
Osteoporotic Fracture And Systemic Skeletal Disorders
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Author : Hideaki E. Takahashi
language : en
Publisher: Springer Nature
Release Date : 2021-11-30
Osteoporotic Fracture And Systemic Skeletal Disorders written by Hideaki E. Takahashi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Medical categories.
This edited book describes what fragile bone is, how the condition is assessed, and how it can be treated. It is intended for multi-professional trainees and practitioners in health and social care fields who care for and treat the elderly. Chapters within the book provide the latest advances in cell and molecular biology, morphology, radiology, and the biomechanics of bone in health and disease. The basic concept of “Remodeling” and “Modeling” is described for better understanding of the mechanisms of osteoporosis. Methods of identifying and assessing osteoporosis are described, as are risk factors for bone fracture and non-unions. Furthermore, the effects of various drugs used to treat osteoporosis at both material and structural levels of bone and their cost effectiveness are described. Operative treatments for fracture that maintain or improve the quality of life of patients are included Treatment of Osteoporotic Fracture and Systemic Skeletal Disorders attempts to provide a holistic and translational view of the pathogenesis and treatment of osteoporosis and some other musculoskeletal diseases, with an overview of treatment modalities in various clinical settings.
Bone Health And Osteoporosis
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Author : United States Public Health Service
language : en
Publisher:
Release Date : 2004-12
Bone Health And Osteoporosis written by United States Public Health Service and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12 with Health & Fitness categories.
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.