Asymmetric Cell Division In Development Differentiation And Cancer
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Asymmetric Cell Division In Development Differentiation And Cancer
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Author : Jean-Pierre Tassan
language : en
Publisher: Springer
Release Date : 2017-04-12
Asymmetric Cell Division In Development Differentiation And Cancer written by Jean-Pierre Tassan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-12 with Science categories.
This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.
Asymmetric Cell Division
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Author : Alvaro Macieira-Coelho
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-21
Asymmetric Cell Division written by Alvaro Macieira-Coelho and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-21 with Science categories.
Cell biologists have recently come to understand that asymmetry of division is an important regulatory phenomenon in the fate of a cell. In adult organisms asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to aging. This book describes the phenomenon in different organisms and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Developmental And Stem Cell Biology In Health And Disease
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Author : Ahmed El-Hashash
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-07-14
Developmental And Stem Cell Biology In Health And Disease written by Ahmed El-Hashash and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-14 with Science categories.
Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embryo culturing and embryonic stem cell extraction in 1981, followed by the work of Thomson in 1998 on the technique for extracting human embryonic stem cells. Since then, stem cell research has rapidly expanded as a therapeutic avenue for different diseases in humans. This book explains the basic developmental biology of stem cells including the development of stem cells during the implantation stage in utero to the regulation of stem cell division. Medical applications of stem cells in the therapy of diseases such as cancer, neurodegenerative diseases, and bone diseases are also explained in subsequent chapters. The book also explains the effect of parasitic cells on stem cell growth. Concepts in the book are explained in a simple clear manner, making this book an informative reference for non-experts, students and professionals in the field of biology and medicine.
Asymmetric Cell Division
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Author : Alvaro Macieira-Coelho
language : en
Publisher: Springer
Release Date : 2007-04-03
Asymmetric Cell Division written by Alvaro Macieira-Coelho and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-03 with Science categories.
Cell biologists have recently come to understand that asymmetry of division is an important regulatory phenomenon in the fate of a cell. In adult organisms asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to aging. This book describes the phenomenon in different organisms and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Stem Cells From Basic Research To Therapy
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Author : Federico Calegari
language : en
Publisher: CRC Press
Release Date : 2014-02-07
Stem Cells From Basic Research To Therapy written by Federico Calegari and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-07 with Medical categories.
The first volume of Stem Cells deals with the fundamental principles that govern embryonic and somatic stem cell biology. Historically, the identification and characterization of such pathways and general rules of stemness occurred during embryonic development and Volume I reflects this with topics spanning cell cycle regulation, epigenetics, and asymmetric cell division in a number of organ systems from planarian to human. Three specific sections discuss i) Basic Stem Cell Biology, ii) Tissue Formation During Development, and iii) Model Organisms with particular emphasis on those more relevant for biomedical research and, thus, leading to the topics addressed in Volume II.
The Growth And Development Of Specialized Cells Tissues And Organs
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Author : Craig C. Freudenrich
language : en
Publisher: The Rosen Publishing Group
Release Date : 2006
The Growth And Development Of Specialized Cells Tissues And Organs written by Craig C. Freudenrich and has been published by The Rosen Publishing Group this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.
Collects articles discussing the specialization of cells, the processes of differentiation that occur in plant and animal cells, and how artificial differentiation can be used and the ethical questions it raises.
Prominin 1 Cd133 New Insights On Stem Cancer Stem Cell Biology
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Author : Denis Corbeil
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-19
Prominin 1 Cd133 New Insights On Stem Cancer Stem Cell Biology written by Denis Corbeil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-19 with Medical categories.
Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.
Germline Stem Cells
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Author : Steven X. Hou
language : en
Publisher: Humana Press
Release Date : 2014-10-15
Germline Stem Cells written by Steven X. Hou and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-15 with Science categories.
In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.
Stem Cell Biology
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Author : Daniel R. Marshak
language : en
Publisher: CSHL Press
Release Date : 2001
Stem Cell Biology written by Daniel R. Marshak and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
Stem cells are the focus of intense interest from a growing, multidisciplinary community of investigators with new tools for isolating and characterizing these elusive cell types. This volume, which features contributions from many of the world's leading laboratories, provides a uniquely broad and authoritative basis for understanding the biology of stem cells and the current excitement about their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their collaborators in the emerging field of regenerative medicine.
Differentiation And Neoplasia
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Author : R. G. McKinnell
language : en
Publisher:
Release Date : 2014-01-15
Differentiation And Neoplasia written by R. G. McKinnell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.