Autoimmune Diseases A Pathophysiological Approach
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Autoimmune Diseases A Pathophysiological Approach
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Author : Dallas Lynch
language : en
Publisher: Hayle Medical
Release Date : 2019-06-19
Autoimmune Diseases A Pathophysiological Approach written by Dallas Lynch and has been published by Hayle Medical this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-19 with Medical categories.
Autoimmune disease is the clinical condition that arises due to an abnormal immune response to a body part. There are around 80 different kinds of autoimmune diseases. Certain common autoimmune diseases are diabetes mellitus type 1, psoriasis, rheumatoid arthritis, multiple sclerosis, etc. The diagnosis of an autoimmune disease can be difficult to determine and depends on the type of the condition or its severity. Autoimmune diseases may have certain pathological effects such as damage or destruction of tissues and altered organ function or organ growth. They may evolve into chronic, debilitating and even life-threatening conditions in some cases. The treatment of an autoimmune disease generally targets the symptoms rather than the disease itself as the causative factor is still not defined. Immunosuppressants, nonsteroidal anti-inflammatory drugs (NSAIDs) and intravenous immunoglobulin are commonly used for treatment. This book explores all the important aspects of autoimmune diseases in modern day healthcare. It strives to provide a fair idea about the diagnosis and treatment of autoimmune diseases and to help develop a better understanding of the latest advances in this area. This book will serve as a reference to a broad spectrum of readers.
Autoimmune Diseases Of The Skin
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Author : Michael Hertl
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Autoimmune Diseases Of The Skin written by Michael Hertl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
Cutaneous autoimmune diseases are often chronic and severe conditions which remain an enigma for many clinicians. Experts in the field here provide a practical guide to identifying and handling these conditions. Unique in its attention to the pathophysiology, clinical diagnosis, and management of these disorders, this book is illustrated with many tables, illustrative figures and clinical color photographs. The chief aim is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and manage these conditions.
The Heart In Rheumatic Autoimmune And Inflammatory Diseases
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Author : Udi Nussinovitch
language : en
Publisher: Academic Press
Release Date : 2017-02-10
The Heart In Rheumatic Autoimmune And Inflammatory Diseases written by Udi Nussinovitch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-10 with Medical categories.
The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
B Cell Receptor Signaling
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Author : Tomohiro Kurosaki
language : en
Publisher: Springer
Release Date : 2015-12-26
B Cell Receptor Signaling written by Tomohiro Kurosaki and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-26 with Medical categories.
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Multi Systemic Auto Immune Diseases
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Author : Louis Kater
language : en
Publisher: Elsevier Science & Technology
Release Date : 1995
Multi Systemic Auto Immune Diseases written by Louis Kater and has been published by Elsevier Science & Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
The views of a group of specialists on multi-systemic auto-immune diseases are brought together in this book, which describes a selection of the diseases according to what has been called an integrated approach. The volume includes descriptions of the clinical picture, histology, laboratory work-up necessary for diagnosis, differential diagnosis, clarification of the mechanisms operative in pathophysiology, specific guidelines for application of immunological laboratory investigations, and practical approaches and advice for therapy. It also gives personal views of the contributors as to which regimen to recommend in a certain situation. internal medicine, dermatology, rheumatology, neurology or immunology.
Autoimmune Diseases Diagnosis Pathophysiology And Treatment
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Author : Marcy Ward
language : en
Publisher:
Release Date : 2023-09-19
Autoimmune Diseases Diagnosis Pathophysiology And Treatment written by Marcy Ward and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.
An autoimmune disease refers to a type of medical condition caused by an abnormal immune response to a healthy body part. The most common types of autoimmune diseases include rheumatoid arthritis (RA), multiple sclerosis, celiac disease, type 1 diabetes, systemic lupus erythematosus (SLE), myasthenia gravis, and inflammatory bowel disease. Majority of the autoimmune diseases share similar signs and symptoms, such as sore muscles, low-grade fever, skin rashes and exhaustion. There are many risk factors associated with autoimmune diseases, such as family history, obesity, smoking and exposure to pollutants. Autoimmune diseases can be diagnosed by performing some blood tests, such as the erythrocyte sedimentation rate (ESR), antinuclear antibody test (ANA) and complete blood count (CBC). Treatment of these diseases is determined by the nature and severity of the condition. Immunosuppressants and nonsteroidal anti-inflammatory medications (NSAIDs) are frequently utilized for the treatment of autoimmune diseases. This book elucidates the innovative models around prospective developments with respect to autoimmune diseases. It is compiled in such a manner, that it will provide in-depth knowledge about the diagnosis, pathophysiology and treatment of these diseases. This book will prove to be immensely beneficial to students and researchers studying these diseases.
Neuroimmunology
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Author : Amanda L. Piquet
language : en
Publisher: Springer
Release Date : 2021-03-09
Neuroimmunology written by Amanda L. Piquet and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-09 with Medical categories.
This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader’s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.
Idiotypes In Medicine Autoimmunity Infection And Cancer
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Author : R.C. Kennedy
language : en
Publisher: Elsevier
Release Date : 1997-11-19
Idiotypes In Medicine Autoimmunity Infection And Cancer written by R.C. Kennedy and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-11-19 with Medical categories.
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Raynaud S Phenomenon
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Author : Fredrick M. Wigley
language : en
Publisher: Springer
Release Date : 2016-09-24
Raynaud S Phenomenon written by Fredrick M. Wigley and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-24 with Medical categories.
Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike. In the last decade, there have been important advances not only in understanding the pathophysiology of Raynaud’s Phenomenon (RP), but also in developing diagnostic methods and effective drug and non-drug therapies. Thoroughly discussing the various manifestations of RP, including childhood RP, RP secondary to connective tissue disease, and a variety of other associated disorders that include vascular perturbation that mimics RP, this title provides a wealth of new information available on normal and abnormal thermoregulation and helps physicians identify the best therapeutic approaches to treating RP. The work offers differential diagnosis options, reviews potential causes such as autoimmune disease, industrial trauma, drugs, and metabolic causes and provides clear recommendations for therapy. Engaging readers with case vignettes and a plethora of visual aids, Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to physicians, patients, and individuals dealing with these disease processes.
Textbook Of The Autoimmune Diseases
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Author : Robert George Lahita
language : en
Publisher:
Release Date : 2000
Textbook Of The Autoimmune Diseases written by Robert George Lahita and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
The Textbook of the Autoimmune Diseases is the definitive reference work about the mechanisms autoimmune diseases employ against the body and the conditions in which they thrive. Whether it's where and how autoimmune diseases disable organs from functioning, or the first symptoms of disease, this book blends both the clinical and the scientific to explain autoimmune diseases' phenomena. The only source for information on heavy metals' and silicone implants' effects on autoimmunity, this book compiles contributions from world-renowned faculty to cut across all fields of medicine, from surgery to internal medicine.