Autoimmune Thrombocytopenia
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Autoimmune Thrombocytopenia
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Author : Yoji Ishida
language : en
Publisher: Springer
Release Date : 2017-06-05
Autoimmune Thrombocytopenia written by Yoji Ishida and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-05 with Medical categories.
This book provides a concise yet comprehensive summary of the current state of knowledge concerning the pathophysiology, differential diagnosis and treatment options that support day-to-day patient management. It reviews a variety of treatments including TOP-R antagonists, along with Syk inhibitor, which has recently proven to be effective, enabling readers to update and broaden their knowledge of the disease. Covering topics ranging from basic science to clinical practice, Autoimmune Thrombocytopenia will appeal to a wide readership, from medical interns and residents to clinicians and hematologists, offering them a thought-provoking, instructive and informative collection of cutting-edge works. Accordingly, readers will gain an overview of the autoimmune and other causes of the disease, and the book will serve as a foundation for new research directions that further our understanding of the pathophysiology and development of diagnosis and treatment options.p>
Immune Hematology
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Author : Jenny M. Despotovic
language : en
Publisher: Springer
Release Date : 2018-05-14
Immune Hematology written by Jenny M. Despotovic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-14 with Medical categories.
This text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children. The book is divided into four sections, each of which focuses on a major autoimmune cytopenia. The first section features background, pathophysiology, presentation, evaluation, and treatment strategies for immune thrombocytopenia (ITP), the most common cause of antibody-mediated platelet destruction. The second section reviews common forms and treatment strategies for autoimmune hemolytic anemia (AIHA), including a chapter dedicated specifically to Evans Syndrome. The third section comprehensively reviews the pathophysiology, diagnosis and current management approaches to thrombotic thrombocytopenic purpura (TTP), a potentially life-threatening autoimmune syndrome. The book concludes with a final section on autoimmune neutropenia. Each section includes a review of common underlying systemic autoimmune conditions and immune deficiency syndromes that can accompany or cause autoimmune cytopenias. Written by experts in each content area, Immune Hematology: Diagnosis and Management of Autoimmune Cytopenias is a valuable resource for clinicians and professionals who treat patients afflicted with autoimmune cytopenias, including primary care providers, hematologist/oncologists, immunologists, among others.
Fast Facts Thrombotic Thrombocytopenic Purpura
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Author : Marie A. Scully
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2020-02-26
Fast Facts Thrombotic Thrombocytopenic Purpura written by Marie A. Scully and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-26 with Medical categories.
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital – mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type – the acquired form – predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives. 'Fast Facts: Thrombotic Thrombocytopenic Purpura' sets out, in a clear and accessible format, the steps to suspecting, diagnosing and treating this potentially devastating disease. These steps are complemented by clear descriptions of the disease mechanism and epidemiology. Differential diagnosis, which is of the utmost importance for this disease, is explored in detail. Contents: • Disease overview • Clinical presentation • Differential diagnosis • Laboratory findings and diagnosis • Management
Heartaches And Miracles
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Author : Greta Burroughs
language : en
Publisher: CreateSpace
Release Date : 2011-08-10
Heartaches And Miracles written by Greta Burroughs and has been published by CreateSpace this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-10 with Self-Help categories.
"But I don't feel sick. Why do I have to stay here in the hospital?" I stubbornly asked the emergency room doctor, and he replied in an exasperated voice, "Because you are one sick chick. Your platelets are down to 2000. You are going upstairs to PCU and you are going to stay there until I say you can go home." I (Greta Burroughs) was diagnosed with an autoimmune disorder called ITP (Idiopathic or Immune Thrombocytopenia Purpura) in April 2005. At that time, I knew very little about platelets, CBC's, corticosteroids and other factors that would play a significant role in my well-being for the rest of my life. Since that time, I have researched autoimmune disorders and ITP and have spoken with a number people who also suffer from this chronic blood disease. I kept a journal describing my relapses, treatments, successes and failures and wrote up all this information so that I could share it with others who are also fighting this illness. Heartaches and Miracles is a combination biography, research information and pep talk for anyone suffering with ITP or for family members and friends who want to understand what this disease is all about. There are excerpts from other ITPers who have been on or are still on the never ending roller coaster ride of steroids, surgery and other types of medications and treatments. There are no cures for ITP or for any autoimmune disorder for that matter. The treatments and medications can have terrible side effects, but the disease can be controlled in most people. It can be a hard road filled with relapses and disappointments but with a positive attitude and support from friends and family, there is hope. Heartaches and Miracles was written as a form of chicken soup for the ITP soul to give encouragement and strength to those affected by this blood disorder. Reading how others have coped, hopefully will give those newly diagnosed a glimpse of what to expect and give everyone with ITP a new hope for tomorrow.
Immune Cytopenias
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Author : Robert McMillan
language : en
Publisher: Churchill Livingstone
Release Date : 1983
Immune Cytopenias written by Robert McMillan and has been published by Churchill Livingstone this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
Immune Thrombocytopenia In Pregnancy
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Author : Patrick Kimuyu
language : en
Publisher: GRIN Verlag
Release Date : 2017-11-22
Immune Thrombocytopenia In Pregnancy written by Patrick Kimuyu and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Essay from the year 2016 in the subject Medicine - Gynecology, Andrology, grade: 2, Egerton University, language: English, abstract: Thrombocytopenia occurs mostly in pregnant women, in which immune thrombocytopenia is believed to be one of the least prevalent forms of thrombocytopenia. Clinical studies indicate that immune thrombocytopenia occurs at a low rate of 11% compared to gestational thrombocytopenia, which occurs at a rate of 59%. However, it is characterized with moderate and severe thrombocytopenia with platelet counts decreasing below 100x109/L. Ordinarily, immune thrombocytopenia is caused by auto-immune reactions against platelets by anti-platelet antibodies, which destroy glycoprotein membranes forming platelet membranes. Immune thrombocytopenia in pregnancy causes several risks to women and newborns. ITP pregnant women experience high risks of maternal hemorrhage compared to those suffering from other forms of thrombocytopenia. Despite the low percentage of ITP rates in pregnant women, extensive monitoring and management are required, primarily during prenatal care to reduce the risks associated with the disorder. On the other hand, immune thrombocytopenia in pregnancy presents numerous neonatal concerns. The notion that, immune thrombocytopenia influences delivery alternatives has been disapproved by the recent clinical reports, which are based on randomized clinical trials. In the past, cesarean delivery was considered as a significant obstetric indication in ITP pregnant women. Currently, vaginal birth has been found to reduce trauma in newborns born of ITP mothers. Moreover, treatment provided to immune thrombocytopenic women prior or during pregnancy causes neonatal concerns. For instance, splenectomy treatment prior to pregnancy has been found to increase free anti-platelet antibodies in maternal circulation, causing a significant risk of anti-platelet reactions in the fetus. It has also been confirmed that IgG anti-platelet antibodies are transferred from maternal circulation into the fetal body, and this may predispose the fetus to neonatal alloimmune thrombocytopenia (NAIT), leading to neonatal hemorrhage. In conclusion, maternal and neonatal concerns associated with ITP can be reduced through platelet count monitoring during prenatal care.
How To Heal A Bruise
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Author : Meghan Brewster
language : en
Publisher:
Release Date : 2015-09-14
How To Heal A Bruise written by Meghan Brewster and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-14 with categories.
Meg was diagnosed with immune thrombocytopenia when she was 22 years old. She struggled to read dense medical journals and scholarly articles to learn more about her ITP. What was missing from the ITP conversation was information from other patients, about what immune thrombocytopenia was really like. In 2012, Meg set up ITPANDME. Three years later, it's one of the largest ITP blogs in the world. Meg has been writing about ITP for more than 6 years, has heard hundreds of patient stories and answered many questions about ITP life from patients and parents.HOW TO HEAL A BRUISE is an honest account of her journey with ITP, as well as practical advice for living with ITP and information from some of her most popular articles.This book takes you through the stages of ITP from coming to terms with your diagnosis to finally accepting and thriving with ITP, what to expect while living with ITP and how to make sure it doesn't take over your life. An honest and informative account of living with an autoimmune disease.
Thrombocytopenic Purpura New Insights For The Healthcare Professional 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Thrombocytopenic Purpura New Insights For The Healthcare Professional 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Thrombocytopenic Purpura: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Thrombocytopenic Purpura in a compact format. The editors have built Thrombocytopenic Purpura: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Thrombocytopenic Purpura in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Thrombocytopenic Purpura: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Immunomodulation By Intravenous Immunoglobulin
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Author : A. Morell
language : en
Publisher: CRC Press
Release Date : 1993-07-15
Immunomodulation By Intravenous Immunoglobulin written by A. Morell and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07-15 with Medical categories.
This work provides a comprehensive review of the role of intravenous immunoglobulins in a wide range of immune-related diseases. Over 20 research workers from America and Europe together examine many important aspects of this subject and, in particular, assess the role of immunoglobulins in the treatment of asthma and allergy, autoimmune disorders, juvenile arthritis and recurrent pregnancy loss.
Thrombotic Thrombocytopenic Purpura
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Author : Mason Hillam
language : en
Publisher:
Release Date : 2019-04-30
Thrombotic Thrombocytopenic Purpura written by Mason Hillam and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with categories.
Thrombotic thrombocytopenic purpura is a life-threatening occlusive disorder of the microcirculation that is characterized by systemic platelet agglutination, organ ischaemia, severe thrombocytopenia and fragmentation of red blood cells. In the opening study included in Thrombotic Thrombocytopenic Purpura: Causes, Diagnosis and Treatment, the authors analyze the principal risk factors and causes of this disorder.Thrombotic thrombocytopenic purpura is diagnosed using standard laboratory tests: in addition to microangi-opathic hemolytic anemia and consumption thrombocytopenia, classical parameters for hemolysis show an elevated reticulocyte count, an undetectable serum haptoglobin concentration, and a markedly elevated lactate dehydrogenase level as well as the presence of schistocytes on the blood smear.The authors propose that there are other pathologies with moderate thrombocytopenia that we should consider, such as: hereditary thrombotic thrombocytopenic purpura, hereditary hemolytic uremic syndrome, and thrombotic microangiopathies associated with some medications, transplantation or hidden malignancies.The closing chapter aims to revise the management of thrombotic thrombocytopenic purpura in pregnant women. To effectively manage this disorder, it is crucial to obtain a prompt diagnosis, in conjunction with further monitoring and treatment, to avoid fetal loss and maternal complications.