Autoimmunity Pathogenesis Clinical Aspects And Therapy Of Specific Autoimmune Diseases
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Autoimmunity
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Author : Katerina Chatzidionysiou
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-06-17
Autoimmunity written by Katerina Chatzidionysiou and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-17 with Medical categories.
Autoimmunity is defined as an immune response against a self-antigen. This abnormal immune response can lead to tissue damage and to the development of autoimmune disease. From organ-specific autoimmune diseases, such as myasthenia gravis, to non-organ-specific, such as systemic lupus erythematosus, autoimmune diseases represent a heterogeneous group of disorders which affect approximately 6% of the population. The pathogenesis of many autoimmune diseases is complex and remains not completely understood. The aim of this book is to present current knowledge regarding pathogenic mechanisms of autoimmune diseases, clinical aspects of specific autoimmune diseases, like vitiligo, celiac disease and autoimmune liver disease, as well as insights regarding specific therapies.
Autoimmunity Pathogenesis Clinical Aspects And Therapy Of Specific Autoimmune Diseases
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Author :
language : en
Publisher:
Release Date : 2015
Autoimmunity Pathogenesis Clinical Aspects And Therapy Of Specific Autoimmune Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Translational Autoimmunity Volume 3
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Author : Nima Rezaei
language : en
Publisher: Academic Press
Release Date : 2022-04-01
Translational Autoimmunity Volume 3 written by Nima Rezaei and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-01 with Medical categories.
Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Covers clinical aspects of autoimmunity and translational immunology studies in autoimmunity in different clinical settings Meets the needs of basic scientists, clinicians, translational scientists and industry partners Supported by a systematic appraisal of the most recent evidence
Infection And Autoimmunity
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Author : Yehuda Shoenfeld
language : en
Publisher: Elsevier
Release Date : 2004-09-18
Infection And Autoimmunity written by Yehuda Shoenfeld and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-18 with Science categories.
Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity. The only book directed at the interactions between infectious agents and autoimmunity Describes the prevalence and incidence of the global issues and current therapeutic approaches Presents the measures for infection control Completely updated, with new chapters One-stop reference with easy access to topics
Autoimmunity
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Author : M. Eric Gershwin
language : en
Publisher: Wiley-Blackwell
Release Date : 2005-06-24
Autoimmunity written by M. Eric Gershwin and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-24 with Medical categories.
Only 40 years ago, the first textbook on autoimmunity was published, and at that time many scientists and clinicians were unconvinced that a process such as autoimmunity even existed. Today, the field is exploding with advances in our understanding of the major histocompatibility complexes, the production of monoclonal antibodies and the resulting identification of distinct cell phenotypes and demonstration of accessory and secondary molecules and messengers, including complement, cytokines, chemokines, and the cognate receptors, to name a few. Both novel scientific (basic immunology) and clinical aspects of autoimmunity and autoimmune diseases are presented in this volume and in Volume 1051 (Autoimmune Disease and Treatment: Organ-Specific and Systemic Disorders) in papers written by the world's leading autoimmunologists. Topics covered in this volumes include etiology and pathogenesis, genetics, mechanisms, tolerance, diagnostics, the role of hormones, infection, animal models, individual autoimmune diseases, therapy, and the art and science of predicting autoimmunity. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Genes And Genetics Of Autoimmunity
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Author : A. N. Theofilopoulos
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 1999
Genes And Genetics Of Autoimmunity written by A. N. Theofilopoulos and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Science categories.
Autoimmunity is one of the most highly investigated areas of immunologic research. The principle of immune system discrimination between self and foreign molecules is fundamental to the survival of the species, and the failure to establish or maintain this discrimination can lead to a wide spectrum of diseases. As a consequence of intensive studies, much has been learned with regard to the normal functioning of the immune system and the editing processes by which self-tolerance is established. Moreover, many theories and experimental models have been developed to explore the mechanisms of autoimmune disease pathogenesis. This book is the first volume of the new series 'Current Directions in Autoimmunity', which aims to consolidate current knowledge of autoimmunity focusing on both basic and clinical aspects. Given that these diseases have a strong genetic basis, it seems appropriate that the first volume addresses this topic. It reviews the most recent findings on genes affecting autoimmunity and genome-wide studies defining the multiple loci predisposing to prominent autoimmune diseases, such as lupus, arthritis, diabetes and multiple sclerosis. For each of these entities, studies in experimental models as well as humans are covered. The authoritative and timely material will be of interest to investigators in the fields of immunology and genetics, to clinicians with interest in rheumatology, endocrinology and neurology, and to those working to devise gene-specific therapies for a variety of inflammatory conditions.
Immunopathogenesis And Immune Based Therapy For Selected Autoimmune Disorders
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Author : Mourad Aribi
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-03-22
Immunopathogenesis And Immune Based Therapy For Selected Autoimmune Disorders written by Mourad Aribi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-22 with Medical categories.
The book Immunopathogenesis and Immune-Based Therapy for Selected Autoimmune Disorders is a synthesis work that discusses two main aspects of autoimmunity: Immunopathogenesis and therapeutic approaches essentially based on the immunotherapies. This book deals with different topics on a number of autoimmune disorders, including type 1 diabetes, autoimmune cardiomyopathy, autoimmunity of gastrointestinal tract, systemic sclerosis, and myasthenia gravis. This book will be useful to clinicians, biologists, researchers, teachers, and students who are interested in immunology and immunopathology.
The Epigenetics Of Autoimmune Diseases
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Author : Moncef Zouali
language : en
Publisher: John Wiley & Sons
Release Date : 2009-04-01
The Epigenetics Of Autoimmune Diseases written by Moncef Zouali and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-01 with Medical categories.
The role of epigenetic mechanisms in autoimmune disease is only now starting to become clear. Understanding these mechanisms, their effect on cellular function and the role of environmental factors is vital to determining how to manage these often debilitating and fatal diseases. Drawing on the research of leading experts, this book provides a valuable insight into this important new area of autoimmunity research and a clear, up-to-date view on the major advances in the field. Specific coverage includes: How highly developed epigenetic mechanisms are involved in several aspects of normal immune regulation, in addition to maintaining immune tolerance to self-determinants. Specific epigenetic aspects of human autoimmune diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, autoimmune diabetes, thyroid autoimmunity, inflammatory bowel disease and autoimmune hepatitis. How understanding epigenetic mechanisms can lead to therapeutic strategies based on manipulation of this previously unexploited facet of immune regulation. Discussion of the novel approaches that are being investigated to prevent or treat autoimmune diseases. This book is an essential resource for those actively involved in the field. It is also of interest to basic researchers interested in understanding the origin of autoimmunity and clinical specialists interested in gaining in-depth understanding of the pathogenesis of autoimmune diseases and their treatment.
Role Of Microorganisms In Pathogenesis And Management Of Autoimmune Diseases
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Author : Mitesh Kumar Dwivedi
language : en
Publisher: Springer Nature
Release Date : 2022-08-10
Role Of Microorganisms In Pathogenesis And Management Of Autoimmune Diseases written by Mitesh Kumar Dwivedi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-10 with Medical categories.
This book in the two volume set provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting into autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases. Contributions in the book focuses on the role of microbiota/probiotics and their distinct mechanisms exerted in management of autoimmune liver, skin, thyroid, rheumatic and myopathic diseases. This could help in better understanding to design therapeutic strategies that can be deployed to prevent these autoimmune diseases. The book has an interdisciplinary appeal and scholars with an interest immunology, medical microbiology and nutritional sciences will value its contribution. Overall, the book gives a new dimensions and insight in the aspects of microbial role in autoimmune disease pathogenesis and therapeutic aspects.
Sjogren S Syndrome
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Author : Alessia Alunno
language : en
Publisher: Academic Press
Release Date : 2016-06-07
Sjogren S Syndrome written by Alessia Alunno and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-07 with Medical categories.
Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus. Discusses heterogeneity of topics and audience, from basic immunology to clinical aspects and therapeutics Provides novel lines of investigation and supports the management of patients requiring novel therapeutic approaches Presents a deeper knowledge on SS clinical management as well as on immunological aspects possibly leading to new lines of investigation Offers a bridge between the clinician and the scientist, and vice versa Provides the reader with most recent and relevant updates due to the novelty of topics