B Cell Development
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Molecular Biology Of B Cells
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Author : Tasuku Honjo
language : en
Publisher: Academic Press
Release Date : 2014-12-22
Molecular Biology Of B Cells written by Tasuku Honjo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-22 with Science categories.
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Molecular Biology Of B Cells
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Author : Tasuku Honjo
language : en
Publisher: Elsevier
Release Date : 2014-10-09
Molecular Biology Of B Cells written by Tasuku Honjo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-09 with Science categories.
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response
Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22
Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
B Cell Receptor Signaling
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Author : Tomohiro Kurosaki
language : en
Publisher: Springer
Release Date : 2015-12-26
B Cell Receptor Signaling written by Tomohiro Kurosaki and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-26 with Medical categories.
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
B Cell Protocols
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Author : Hua Gu
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
B Cell Protocols written by Hua Gu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
B-lymphocyte development and function remains an exciting area of research for those interested in the physiology and pathology of the immune system in higher animals. While recent advances in genetics and cellular and molecular biology have provided a large spectrum of powerful new experimental tools in this field, it is both time consuming and often very difficult for a student or just any bench-side worker to identify a reliable experimental protocol in the ocean of the literature. The aim of B Cell Protocols is to provide a collection of diverse protocols ranging from the latest inventions and applications to some classic, but still frequently used methods in B-cell biology. The authors of the various chapters are all highly qualified scientists who are either the inventors or expert users of these methods. Their extensive experience in mastering a particular method provides not only the step-by-step details of a reproducible protocol, but also useful troubleshooting tips that readers will appreciate in their daily work. We hope that this book will be helpful for both beginning and experienced researchers in the field in designing or modifying an experimental approach, and exploring a biological question from multiple angles.
Normal And Malignant B Cell
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Author : Mourad Aribi
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-02-26
Normal And Malignant B Cell written by Mourad Aribi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-26 with Medical categories.
Normal and Malignant B-Cell is a collection of harmonious chapters contributed by different authors. This book sets out to describe the B-cell during different stages of ontogeny and the molecular mechanisms of its antigen receptor diversity. It also discusses the main clinical and etiopathogenic aspects when it is transformed into a malignant cell. The book will be interesting and useful for clinicians, biologists, researchers, teachers, and graduate students of both doctoral and master's degrees in the field of immunology.
B Cell Development
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Author : Owen N. Witte
language : en
Publisher: Wiley-Liss
Release Date : 1988-10-15
B Cell Development written by Owen N. Witte and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-10-15 with Science categories.
Describes the molecular biology and regulation of B cell repertoire expression, B cell triggering and tolerance induction, and the role of defined interleukins in B cell development, differentiation, and isotope expression. Also covers in vivo development in neonates and adults and the role of defined in vivo systems for B cell development. Discusses B cell subpopulations, autoimmunity, and immunodeficient states, and gives details on the use of transgenic mice for analyzing B cell development and regulation.
B Cells In Immunity And Tolerance
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Author : Ji-Yang Wang
language : en
Publisher: Springer Nature
Release Date : 2020-04-22
B Cells In Immunity And Tolerance written by Ji-Yang Wang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-22 with Medical categories.
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
Antibodies
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Author : A. Szentivanyi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
Antibodies written by A. Szentivanyi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
This publication is based on a Symposium that has been held in Clearwater, Florida on February 19-21, 1986, on antibodies, their structure, synthesis, function, and clinical applicability in disease. Organization of this symposium by the University of South Florida College of Medicine was prompted by the unparalleled current expansion of information on these topics in general, and in the field of antibody diver sity, in particular. The issues that surround the last named dimension of this field, began to surface in the late 1950's with the first conclusive genetic studies having been answered, and a new set of concepts has been de fined. As we see it from the material presented in this volume, now new and different questions are being raised and answered by studies in progress, and it may be expected that there will be other questions that will be with us for a considerably longer time. We believe that the symposium brought together many prominent investi gators with different backgrounds and training experiences such as immunolo gists, microbiologists, biochemists, molecular biologists, and clinical sci entists, thus providing an excellent example of the interdisciplinary value of modern immunology and modern biomedical science in general. We believe, therefore, that bringing these complex topics to a wide audience of bio medical scientists through this symposium as well as this volume is of value to the scientific and to the medical community.
Mechanisms Of Lymphocyte Activation And Immune Regulation Xi
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-21
Mechanisms Of Lymphocyte Activation And Immune Regulation Xi written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-21 with Medical categories.
In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.