Basic Mechanisms Of The Epilepsies
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The Causes Of Epilepsy
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Author : Simon D. Shorvon
language : en
Publisher: Cambridge University Press
Release Date : 2011-04-14
The Causes Of Epilepsy written by Simon D. Shorvon and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-14 with Medical categories.
Causation is an aspect of epilepsy neglected in the scientific literature and in the conceptualization of epilepsy at a clinical and experimental level. It was to remedy this deficiency that this book was conceived. The book opens with a draft etiological classification that goes some way to filling the nosological void. The book is divided into four etiological categories: idiopathic, symptomatic, cryptogenic, and provoked epilepsies. Each chapter considers topics in a consistent fashion, dealing with the phenomenon of epilepsy in each etiology, including its epidemiology, clinical features and prognosis, and any specific aspects of treatment. The book is a comprehensive reference work, a catalogue of all important causes of epilepsy, and a clinical tool for all clinicians dealing with patients who have epilepsy. It is aimed at epileptologists and neurologists and provides a distillation of knowledge in a form that is helpful in the clinical setting.
Introduction To Epilepsy
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Author : Gonzalo Alarcón
language : en
Publisher: Cambridge University Press
Release Date : 2012-04-26
Introduction To Epilepsy written by Gonzalo Alarcón and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-26 with Medical categories.
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
Jasper S Basic Mechanisms Of The Epilepsies
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Author : Jeffrey Noebels
language : en
Publisher: OUP USA
Release Date : 2012-06-29
Jasper S Basic Mechanisms Of The Epilepsies written by Jeffrey Noebels and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-29 with Medical categories.
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Astrocytes And Epilepsy
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Author : Jacqueline A. Hubbard
language : en
Publisher: Academic Press
Release Date : 2016-07-05
Astrocytes And Epilepsy written by Jacqueline A. Hubbard and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-05 with Medical categories.
Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. - Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume - Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions - Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation
Epilepsy
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Author : Jong Rho
language : en
Publisher: CRC Press
Release Date : 2010-06-18
Epilepsy written by Jong Rho and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-18 with Medical categories.
Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo
Pediatric Epilepsy
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Author : Blaise F. Bourgeois
language : en
Publisher: Demos Medical Publishing
Release Date : 2007-12-16
Pediatric Epilepsy written by Blaise F. Bourgeois and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-16 with Medical categories.
The extensively updated third edition of Pediatric Epilepsy: Diagnosis and Therapy continues to be the definitive volume on the diagnosis, treatment, classification, and management of the childhood epilepsies. Written by nearly 100 international leaders in the field, this new edition progresses logically with major sections on the basic mechanisms of the disease, classification, epidemiology, etiology, diagnosis, and age-related syndromes of epilepsy. The core of the new third edition is its completely updated section on antiepileptic drugs, including an in-depth discussion of dosage considerations, drug toxicity, teratogenicity, and drug interactions, with recommendations for optimal combinations when multiple drug therapy is required. Features unique to the third edition include: Expanded section on the basic science and mechanism of epilepsy Completely updated drug chapters, including newly released drugs and those in development Expanded chapters on vagus nerve stimulation and surgical treatment Expanded section on co-morbidities The third edition includes 21 new chapters, including discussions of: epileptic channelopathies; epileptogenic cerebral cortical malformation; epilepsy genes; etiologies and workup; evidence-based medicine issues related to drug selection; Levetiracetam; Sulthiame; Pregabalin; herbal medications; basic and advanced imaging; immunotherapy issues; vagus nerve stimulation therapy; cognitive and psychiatric co-morbidities and educational placement; and psychosocial aspects of epilepsy.
Epilepsy And Brain Tumors
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Author : Herbert B. Newton
language : en
Publisher: Elsevier
Release Date : 2015-03-06
Epilepsy And Brain Tumors written by Herbert B. Newton and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-06 with Medical categories.
Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. - Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors - Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more - Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available
Epilepsy Bibliography 1950 1975
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Author : J. Kiffin Penry
language : en
Publisher:
Release Date : 1976
Epilepsy Bibliography 1950 1975 written by J. Kiffin Penry and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Epilepsy categories.
1771 entries to worldwide literature (mostly journal articles). Intended as source of current published works on epilepsy; also serves as cumulative index to Epilepsy abstracts, v. 1-9, 1967-1976. Classified arrangement under 9 broad headings, e.g., Seizures, Etiology, and Treatment. Entries include bibliographical information, with foreign-language titles also in English, and Epilepsy abstracts citations. Keyword, subject indexes.
Neuronal Substrates Of Sleep And Epilepsy
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Author : Mircea Steriade
language : en
Publisher: Cambridge University Press
Release Date : 2003-05-08
Neuronal Substrates Of Sleep And Epilepsy written by Mircea Steriade and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-08 with Medical categories.
Conventional wisdom assumes that sleep is a resting state of the brain, with negligible activity of cortical neurons. Here, the author brings new evidence favoring the idea that during sleep, memory traces acquired while awake are consolidated. Mircea Steriade focuses on the coalescence of different sleep rhythms in interacting corticothalamic networks and on three types of paroxysmal disorders: spike-wave seizures as in absence epilepsy, Lennox-Gastaut seizures, and temporal-lobe epilepsy. Many physiological correlates of waking and sleep states as well as diverse types of epileptic seizures are also discussed.
Indexes To The Epilepsy Accessions Of The Epilepsy Information System
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Author : J. Kiffin Penry
language : en
Publisher:
Release Date : 1978
Indexes To The Epilepsy Accessions Of The Epilepsy Information System written by J. Kiffin Penry and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Epilepsy categories.