Basic Science Methods For Clinical Researchers


Basic Science Methods For Clinical Researchers
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Basic Science Methods For Clinical Researchers


Basic Science Methods For Clinical Researchers
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Author : Morteza Jalali
language : en
Publisher: Academic Press
Release Date : 2017-03-31

Basic Science Methods For Clinical Researchers written by Morteza Jalali and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-31 with Science categories.


Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)



Basic Science Techniques In Clinical Practice


Basic Science Techniques In Clinical Practice
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Author : Hitendra R.H. Patel
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-25

Basic Science Techniques In Clinical Practice written by Hitendra R.H. Patel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-25 with Medical categories.


A complete guide to implementing research projects for anyone in the medical professions. This book covers all the main areas, allowing anyone to set up and complete research projects. The techniques outlined here can easily be adapted to clinical projects. Written by international authors to provide a flavor from many institutions, the book’s appeal is cross-sectional, both at hospital and primary care levels worldwide. Providing cutting-edge information in an accessible manner, and containing diagrams and easy-to-follow step-by-step guides, this is the first guide of its kind. It contains a complete section on setting up and funding research projects.



Principles Of Research Methodology


Principles Of Research Methodology
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Author : Phyllis G. Supino
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-22

Principles Of Research Methodology written by Phyllis G. Supino and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-22 with Medical categories.


Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.



Social Science Methods In Health Research


Social Science Methods In Health Research
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Author : Abraham Rudnick
language : en
Publisher: SAGE Publications Pvt. Limited
Release Date : 2017-04-13

Social Science Methods In Health Research written by Abraham Rudnick and has been published by SAGE Publications Pvt. Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-13 with Medical categories.


The six-volume Social Science Methods in Health Research set comprehensively addresses research methods used in social science for the health sector. The six volumes are illustrative and indicative of the range of social science methods in health research. It is ordered in large part according to the scope of the research questions covering the micro-, meso-, and mega-levels of health research. The first three volumes, Foundations, Basic Science and Clinical Research focuses mainly on micro- and meso-level studies. Volume 1 centres on the foundations of social science research, including history, ethics, and more. Volume 2 addresses the use of social science methods in basic biomedical studies involving humans and other animals, while Volume 3, the last volume provides insight into the importance of using social science methods in clinical research. Volumes 4-6, cover Organizations, Systems and Public Health Research, and address research methods that can be used to study health related issues in broad contexts, mainly at the mega-level. Volume 4 addresses methodological issues particular to studying health care organizations and how those organizations can be studied using methods from the social sciences including case studies, leadership research, and more. Volume 5 explores how social science methods can be used to study health care systems (across and beyond health care organizations), including policy studies, systems research, and more. Volume 6, the final volume focuses on social science methods in public health research, including population research, social determinants studies, and more.



Clinical Research Computing


Clinical Research Computing
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Author : Prakash Nadkarni
language : en
Publisher: Academic Press
Release Date : 2016-04-29

Clinical Research Computing written by Prakash Nadkarni and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-29 with Medical categories.


Clinical Research Computing: A Practitioner’s Handbook deals with the nuts-and-bolts of providing informatics and computing support for clinical research. The subjects that the practitioner must be aware of are not only technological and scientific, but also organizational and managerial. Therefore, the author offers case studies based on real life experiences in order to prepare the readers for the challenges they may face during their experiences either supporting clinical research or supporting electronic record systems. Clinical research computing is the application of computational methods to the broad field of clinical research. With the advent of modern digital computing, and the powerful data collection, storage, and analysis that is possible with it, it becomes more relevant to understand the technical details in order to fully seize its opportunities. Offers case studies, based on real-life examples where possible, to engage the readers with more complex examples Provides studies backed by technical details, e.g., schema diagrams, code snippets or algorithms illustrating particular techniques, to give the readers confidence to employ the techniques described in their own settings Offers didactic content organization and an increasing complexity through the chapters



Clinical Epidemiology


Clinical Epidemiology
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Author : David L. Sackett
language : en
Publisher: Little, Brown Medical Division
Release Date : 1985

Clinical Epidemiology written by David L. Sackett and has been published by Little, Brown Medical Division this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Clinical epidemiology categories.




Essentials Of Clinical Research


Essentials Of Clinical Research
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Author : Stephen P. Glasser
language : en
Publisher: Springer
Release Date : 2014-06-02

Essentials Of Clinical Research written by Stephen P. Glasser and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-02 with Medical categories.


In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations. Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.



Fundamentals Of Research Methodology For Health Care Professionals


Fundamentals Of Research Methodology For Health Care Professionals
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Author : Hilla Brink
language : en
Publisher: Juta and Company Ltd
Release Date : 2006

Fundamentals Of Research Methodology For Health Care Professionals written by Hilla Brink and has been published by Juta and Company Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical care categories.


An introduction to research methodology, this textbook contains conceptual and nontechnical descriptions of the methods used by researchers in medical experimentation. Each step of the research process is explained and illustrated with examples from practice. This revised second edition also has expanded sections on clinical research methods, action research, Web resources, and current scenarios.



Principles Of Research Methodology


Principles Of Research Methodology
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Author : Phyllis G. Supino
language : en
Publisher: Springer
Release Date : 2012-06-23

Principles Of Research Methodology written by Phyllis G. Supino and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-23 with Medical categories.


Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.



Essential Concepts In Clinical Research


Essential Concepts In Clinical Research
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Author : Kenneth Schulz
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-07-19

Essential Concepts In Clinical Research written by Kenneth Schulz and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-19 with Medical categories.


This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials. Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods. Written by leaders in the field of clinical research who have published extensively with authorship of hundreds of articles in medical journals. The authorship includes one of the three authors of the CONSORT guidelines for the reporting of randomized controlled trials. The book presents the essential concepts to a wide array of topics including randomized control trials, descriptive studies, cohort studies, case-control studies, bias, and screening tests. The book utilises a readable and humorous prose style, lightening what can be a difficult area for clinical readers. Derived from decades of teaching clinical research in seminar settings the book will empower clinicians to make sense of, and critically appraise, current medical research and will enable researchers to enrich the quality of their work. The updated new edition includes six new chapters: Surrogate endpoints Limitations of observational epidemiology Participant recruitment Practicalities of double-blinding Randomized trials in the context of a prospective meta-analysis Reporting studies in medical journals: CONSORT