Batch Effects And Noise In Microarray Experiments

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Batch Effects And Noise In Microarray Experiments
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Author : Andreas Scherer
language : en
Publisher: John Wiley & Sons
Release Date : 2009-11-03
Batch Effects And Noise In Microarray Experiments written by Andreas Scherer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-03 with Science categories.
Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.
Batch Effects And Noise In Microarray Experiments
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Author : Andreas Scherer
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-14
Batch Effects And Noise In Microarray Experiments written by Andreas Scherer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-14 with Science categories.
Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.
The Analysis Of Gene Expression Data
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Author : Giovanni Parmigiani
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
The Analysis Of Gene Expression Data written by Giovanni Parmigiani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
This book presents practical approaches for the analysis of data from gene expression micro-arrays. It describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools. The materials presented cover a range of software tools designed for varied audiences.
Causality
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Author : Carlo Berzuini
language : en
Publisher: John Wiley & Sons
Release Date : 2012-06-04
Causality written by Carlo Berzuini and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-04 with Mathematics categories.
A state of the art volume on statistical causality Causality: Statistical Perspectives and Applications presents a wide-ranging collection of seminal contributions by renowned experts in the field, providing a thorough treatment of all aspects of statistical causality. It covers the various formalisms in current use, methods for applying them to specific problems, and the special requirements of a range of examples from medicine, biology and economics to political science. This book: Provides a clear account and comparison of formal languages, concepts and models for statistical causality. Addresses examples from medicine, biology, economics and political science to aid the reader's understanding. Is authored by leading experts in their field. Is written in an accessible style. Postgraduates, professional statisticians and researchers in academia and industry will benefit from this book.
Introduction To Time Series Analysis And Forecasting
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Author : Douglas C. Montgomery
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-27
Introduction To Time Series Analysis And Forecasting written by Douglas C. Montgomery and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-27 with Mathematics categories.
Praise for the First Edition "...[t]he book is great for readers who need to apply the methods and models presented but have little background in mathematics and statistics." -MAA Reviews Thoroughly updated throughout, Introduction to Time Series Analysis and Forecasting, Second Edition presents the underlying theories of time series analysis that are needed to analyze time-oriented data and construct real-world short- to medium-term statistical forecasts. Authored by highly-experienced academics and professionals in engineering statistics, the Second Edition features discussions on both popular and modern time series methodologies as well as an introduction to Bayesian methods in forecasting. Introduction to Time Series Analysis and Forecasting, Second Edition also includes: Over 300 exercises from diverse disciplines including health care, environmental studies, engineering, and finance More than 50 programming algorithms using JMP®, SAS®, and R that illustrate the theory and practicality of forecasting techniques in the context of time-oriented data New material on frequency domain and spatial temporal data analysis Expanded coverage of the variogram and spectrum with applications as well as transfer and intervention model functions A supplementary website featuring PowerPoint® slides, data sets, and select solutions to the problems Introduction to Time Series Analysis and Forecasting, Second Edition is an ideal textbook upper-undergraduate and graduate-levels courses in forecasting and time series. The book is also an excellent reference for practitioners and researchers who need to model and analyze time series data to generate forecasts.
Research In Computational Molecular Biology
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Author : Martin Vingron
language : en
Publisher: Springer
Release Date : 2008-04-03
Research In Computational Molecular Biology written by Martin Vingron and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-03 with Computers categories.
This book constitutes the refereed proceedings of the 12th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2008. It presents current issues in algorithmic, theoretical, and experimental bioinformatics.
Handbook Of Regression Analysis With Applications In R
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Author : Samprit Chatterjee
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-30
Handbook Of Regression Analysis With Applications In R written by Samprit Chatterjee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-30 with Mathematics categories.
Handbook and reference guide for students and practitioners of statistical regression-based analyses in R Handbook of Regression Analysis with Applications in R, Second Edition is a comprehensive and up-to-date guide to conducting complex regressions in the R statistical programming language. The authors' thorough treatment of "classical" regression analysis in the first edition is complemented here by their discussion of more advanced topics including time-to-event survival data and longitudinal and clustered data. The book further pays particular attention to methods that have become prominent in the last few decades as increasingly large data sets have made new techniques and applications possible. These include: Regularization methods Smoothing methods Tree-based methods In the new edition of the Handbook, the data analyst's toolkit is explored and expanded. Examples are drawn from a wide variety of real-life applications and data sets. All the utilized R code and data are available via an author-maintained website. Of interest to undergraduate and graduate students taking courses in statistics and regression, the Handbook of Regression Analysis will also be invaluable to practicing data scientists and statisticians.
Multivariate Time Series Analysis
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Author : Ruey S. Tsay
language : en
Publisher: John Wiley & Sons
Release Date : 2013-11-11
Multivariate Time Series Analysis written by Ruey S. Tsay and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Mathematics categories.
An accessible guide to the multivariate time series tools used in numerous real-world applications Multivariate Time Series Analysis: With R and Financial Applications is the much anticipated sequel coming from one of the most influential and prominent experts on the topic of time series. Through a fundamental balance of theory and methodology, the book supplies readers with a comprehensible approach to financial econometric models and their applications to real-world empirical research. Differing from the traditional approach to multivariate time series, the book focuses on reader comprehension by emphasizing structural specification, which results in simplified parsimonious VAR MA modeling. Multivariate Time Series Analysis: With R and Financial Applications utilizes the freely available R software package to explore complex data and illustrate related computation and analyses. Featuring the techniques and methodology of multivariate linear time series, stationary VAR models, VAR MA time series and models, unitroot process, factor models, and factor-augmented VAR models, the book includes: • Over 300 examples and exercises to reinforce the presented content • User-friendly R subroutines and research presented throughout to demonstrate modern applications • Numerous datasets and subroutines to provide readers with a deeper understanding of the material Multivariate Time Series Analysis is an ideal textbook for graduate-level courses on time series and quantitative finance and upper-undergraduate level statistics courses in time series. The book is also an indispensable reference for researchers and practitioners in business, finance, and econometrics.
Extremes In Random Fields
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Author : Benjamin Yakir
language : en
Publisher: John Wiley & Sons
Release Date : 2013-08-01
Extremes In Random Fields written by Benjamin Yakir and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-01 with Mathematics categories.
Presents a useful new technique for analyzing the extreme-value behaviour of random fields Modern science typically involves the analysis of increasingly complex data. The extreme values that emerge in the statistical analysis of complex data are often of particular interest. This book focuses on the analytical approximations of the statistical significance of extreme values. Several relatively complex applications of the technique to problems that emerge in practical situations are presented. All the examples are difficult to analyze using classical methods, and as a result, the author presents a novel technique, designed to be more accessible to the user. Extreme value analysis is widely applied in areas such as operational research, bioinformatics, computer science, finance and many other disciplines. This book will be useful for scientists, engineers and advanced graduate students who need to develop their own statistical tools for the analysis of their data. Whilst this book may not provide the reader with the specific answer it will inspire them to rethink their problem in the context of random fields, apply the method, and produce a solution.
Structural Equation Modeling
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Author : Jichuan Wang
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-05
Structural Equation Modeling written by Jichuan Wang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-05 with Mathematics categories.
Presents a useful guide for applications of SEM whilst systematically demonstrating various SEM models using Mplus Focusing on the conceptual and practical aspects of Structural Equation Modeling (SEM), this book demonstrates basic concepts and examples of various SEM models, along with updates on many advanced methods, including confirmatory factor analysis (CFA) with categorical items, bifactor model, Bayesian CFA model, item response theory (IRT) model, graded response model (GRM), multiple imputation (MI) of missing values, plausible values of latent variables, moderated mediation model, Bayesian SEM, latent growth modeling (LGM) with individually varying times of observations, dynamic structural equation modeling (DSEM), residual dynamic structural equation modeling (RDSEM), testing measurement invariance of instrument with categorical variables, longitudinal latent class analysis (LLCA), latent transition analysis (LTA), growth mixture modeling (GMM) with covariates and distal outcome, manual implementation of the BCH method and the three-step method for mixture modeling, Monte Carlo simulation power analysis for various SEM models, and estimate sample size for latent class analysis (LCA) model. The statistical modeling program Mplus Version 8.2 is featured with all models updated. It provides researchers with a flexible tool that allows them to analyze data with an easy-to-use interface and graphical displays of data and analysis results. Intended as both a teaching resource and a reference guide, and written in non-mathematical terms, Structural Equation Modeling: Applications Using Mplus, 2nd edition provides step-by-step instructions of model specification, estimation, evaluation, and modification. Chapters cover: Confirmatory Factor Analysis (CFA); Structural Equation Models (SEM); SEM for Longitudinal Data; Multi-Group Models; Mixture Models; and Power Analysis and Sample Size Estimate for SEM. Presents a useful reference guide for applications of SEM while systematically demonstrating various advanced SEM models Discusses and demonstrates various SEM models using both cross-sectional and longitudinal data with both continuous and categorical outcomes Provides step-by-step instructions of model specification and estimation, as well as detailed interpretation of Mplus results using real data sets Introduces different methods for sample size estimate and statistical power analysis for SEM Structural Equation Modeling is an excellent book for researchers and graduate students of SEM who want to understand the theory and learn how to build their own SEM models using Mplus.