Bayesian Methods For Measures Of Agreement


Bayesian Methods For Measures Of Agreement
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Bayesian Methods For Measures Of Agreement


Bayesian Methods For Measures Of Agreement
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2009-01-12

Bayesian Methods For Measures Of Agreement written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-12 with Mathematics categories.


Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process. The author employs a Bayesian approach to provide statistical inferences based on various models of intra- and interrater agreement. He presents many examples that illustrate the Bayesian mode of reasoning and explains elements of a Bayesian application, including prior information, experimental information, the likelihood function, posterior distribution, and predictive distribution. The appendices provide the necessary theoretical foundation to understand Bayesian methods as well as introduce the fundamentals of programming and executing the WinBUGS software. Taking a Bayesian approach to inference, this hands-on book explores numerous measures of agreement, including the Kappa coefficient, the G coefficient, and intraclass correlation. With examples throughout and end-of-chapter exercises, it discusses how to successfully design and analyze an agreement study.



Bayesian Methods For Repeated Measures


Bayesian Methods For Repeated Measures
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2015-08-04

Bayesian Methods For Repeated Measures written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-04 with Mathematics categories.


Analyze Repeated Measures Studies Using Bayesian TechniquesGoing beyond standard non-Bayesian books, Bayesian Methods for Repeated Measures presents the main ideas for the analysis of repeated measures and associated designs from a Bayesian viewpoint. It describes many inferential methods for analyzing repeated measures in various scientific areas,



Advanced Bayesian Methods For Medical Test Accuracy


Advanced Bayesian Methods For Medical Test Accuracy
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Advanced Bayesian Methods For Medical Test Accuracy written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.


Useful in many areas of medicine and biology, Bayesian methods are particularly attractive tools for the design of clinical trials and diagnostic tests, which are based on established information, usually from related previous studies. Advanced Bayesian Methods for Medical Test Accuracy begins with a review of the usual measures such as specificity, sensitivity, positive and negative predictive value, and the area under the ROC curve. Then the scope expands to cover the more advanced topics of verification bias, diagnostic tests with imperfect gold standards, and those for which no gold standard is available. Promoting accuracy and efficiency of clinical trials, tests, and the diagnostic process, this book: Enables the user to efficiently apply prior information via a WinBUGS package Presents many ideas for the first time and goes far beyond the two standard references Integrates reader agreement with different modalities—X-ray, CT Scanners, and more—to study their effect on medical test accuracy Provides practical chapter-end problems Useful for graduate students and consulting statisticians working in the various areas of diagnostic medicine and study design, this practical resource introduces the fundamentals of programming and executing BUGS, giving readers the tools and experience to successfully analyze studies for medical test accuracy.



Bayesian Inference For Stochastic Processes


Bayesian Inference For Stochastic Processes
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2017-12-12

Bayesian Inference For Stochastic Processes written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-12 with Mathematics categories.


This is the first book designed to introduce Bayesian inference procedures for stochastic processes. There are clear advantages to the Bayesian approach (including the optimal use of prior information). Initially, the book begins with a brief review of Bayesian inference and uses many examples relevant to the analysis of stochastic processes, including the four major types, namely those with discrete time and discrete state space and continuous time and continuous state space. The elements necessary to understanding stochastic processes are then introduced, followed by chapters devoted to the Bayesian analysis of such processes. It is important that a chapter devoted to the fundamental concepts in stochastic processes is included. Bayesian inference (estimation, testing hypotheses, and prediction) for discrete time Markov chains, for Markov jump processes, for normal processes (e.g. Brownian motion and the Ornstein–Uhlenbeck process), for traditional time series, and, lastly, for point and spatial processes are described in detail. Heavy emphasis is placed on many examples taken from biology and other scientific disciplines. In order analyses of stochastic processes, it will use R and WinBUGS. Features: Uses the Bayesian approach to make statistical Inferences about stochastic processes The R package is used to simulate realizations from different types of processes Based on realizations from stochastic processes, the WinBUGS package will provide the Bayesian analysis (estimation, testing hypotheses, and prediction) for the unknown parameters of stochastic processes To illustrate the Bayesian inference, many examples taken from biology, economics, and astronomy will reinforce the basic concepts of the subject A practical approach is implemented by considering realistic examples of interest to the scientific community WinBUGS and R code are provided in the text, allowing the reader to easily verify the results of the inferential procedures found in the many examples of the book Readers with a good background in two areas, probability theory and statistical inference, should be able to master the essential ideas of this book.



Case Studies In Bayesian Statistical Modelling And Analysis


Case Studies In Bayesian Statistical Modelling And Analysis
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Author : Clair L. Alston
language : en
Publisher: John Wiley & Sons
Release Date : 2012-10-10

Case Studies In Bayesian Statistical Modelling And Analysis written by Clair L. Alston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-10 with Mathematics categories.


Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.



Quantitative Methods For Hiv Aids Research


Quantitative Methods For Hiv Aids Research
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Author : Cliburn Chan
language : en
Publisher: CRC Press
Release Date : 2017-08-07

Quantitative Methods For Hiv Aids Research written by Cliburn Chan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-07 with Mathematics categories.


Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors’ hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.



Applied Surrogate Endpoint Evaluation Methods With Sas And R


Applied Surrogate Endpoint Evaluation Methods With Sas And R
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Author : Ariel Alonso
language : en
Publisher: CRC Press
Release Date : 2016-11-30

Applied Surrogate Endpoint Evaluation Methods With Sas And R written by Ariel Alonso and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-30 with Mathematics categories.


An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.



Statistical Methods For Healthcare Performance Monitoring


Statistical Methods For Healthcare Performance Monitoring
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Author : Alex Bottle
language : en
Publisher: CRC Press
Release Date : 2016-08-05

Statistical Methods For Healthcare Performance Monitoring written by Alex Bottle and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-05 with Mathematics categories.


Healthcare is important to everyone, yet large variations in its quality have been well documented both between and within many countries. With demand and expenditure rising, it’s more crucial than ever to know how well the healthcare system and all its components – from staff member to regional network – are performing. This requires data, which inevitably differ in form and quality. It also requires statistical methods, the output of which needs to be presented so that it can be understood by whoever needs it to make decisions. Statistical Methods for Healthcare Performance Monitoring covers measuring quality, types of data, risk adjustment, defining good and bad performance, statistical monitoring, presenting the results to different audiences and evaluating the monitoring system itself. Using examples from around the world, it brings all the issues and perspectives together in a largely non-technical way for clinicians, managers and methodologists. Statistical Methods for Healthcare Performance Monitoring is aimed at statisticians and researchers who need to know how to measure and compare performance, health service regulators, health service managers with responsibilities for monitoring performance, and quality improvement scientists, including those involved in clinical audits.



Statistical Tools For Measuring Agreement


Statistical Tools For Measuring Agreement
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Author : Lawrence Lin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-30

Statistical Tools For Measuring Agreement written by Lawrence Lin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-30 with Mathematics categories.


Agreement assessment techniques are widely used in examining the acceptability of a new or generic process, methodology and/or formulation in areas of lab performance, instrument/assay validation or method comparisons, statistical process control, goodness-of-fit, and individual bioequivalence. Successful applications in these situations require a sound understanding of both the underlying theory and methodological advances in handling real-life problems. This book seeks to effectively blend theory and applications while presenting readers with many practical examples. For instance, in the medical device environment, it is important to know if the newly established lab can reproduce the instrument/assay results from the established but outdating lab. When there is a disagreement, it is important to differentiate the sources of disagreement. In addition to agreement coefficients, accuracy and precision coefficients are introduced and utilized to characterize these sources. This book will appeal to a broad range of statisticians, researchers, practitioners and students, in areas of biomedical devices, psychology, medical research, and others, in which agreement assessment are needed. Many practical illustrative examples will be presented throughout the book in a wide variety of situations for continuous and categorical data.



Methods In Comparative Effectiveness Research


Methods In Comparative Effectiveness Research
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Author : Constantine Gatsonis
language : en
Publisher: CRC Press
Release Date : 2017-02-24

Methods In Comparative Effectiveness Research written by Constantine Gatsonis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-24 with Mathematics categories.


Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009). CER is conducted to develop evidence that will aid patients, clinicians, purchasers, and health policy makers in making informed decisions at both the individual and population levels. CER encompasses a very broad range of types of studies—experimental, observational, prospective, retrospective, and research synthesis. This volume covers the main areas of quantitative methodology for the design and analysis of CER studies. The volume has four major sections—causal inference; clinical trials; research synthesis; and specialized topics. The audience includes CER methodologists, quantitative-trained researchers interested in CER, and graduate students in statistics, epidemiology, and health services and outcomes research. The book assumes a masters-level course in regression analysis and familiarity with clinical research.