Behavioral Neurogenomics
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Behavioral Neurogenomics
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Author : Elisabeth B. Binder
language : en
Publisher: Springer Nature
Release Date : 2019-12-12
Behavioral Neurogenomics written by Elisabeth B. Binder and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-12 with Medical categories.
This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint and the effort to establish functional connection between genetic variants and behavioral phenotypes. Particular attention is given to the broad spectrum of epigenetic mechanisms and behavior. The chapter 'Role of MicoRNAs in Anxiety and Anxiety-Related Disorders' is available open access under a CC BY 4.0 license at link.springer.com
Behavioral Neurogenetics
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Author : John F. Cryan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-05-04
Behavioral Neurogenetics written by John F. Cryan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-04 with Medical categories.
This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.
Behavioral Neurogenetics
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Author : John F. Cryan
language : en
Publisher: Springer
Release Date : 2012-05-09
Behavioral Neurogenetics written by John F. Cryan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-09 with Medical categories.
This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.
Neurobehavioral Genetics
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Author : Byron C. Jones
language : en
Publisher: CRC Press
Release Date : 2006-08-30
Neurobehavioral Genetics written by Byron C. Jones and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-30 with Medical categories.
A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De
Our Genes Our Choices
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Author : David Goldman
language : en
Publisher: Elsevier
Release Date : 2023-09-04
Our Genes Our Choices written by David Goldman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-04 with Science categories.
Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior, Second Edition explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes, which direct neurodevelopmental sequences. Are people free to make choices, or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. Here, author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures, a combination of factors that we choose and do not choose. Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces the topics of epigenetics and the predictive power of behavioral genetics. In the decade since the first edition published, knowledge of genetic influences on the neurogenetic underpinnings of behavior has been transformed by genomic technologies. Genome-Wide Association studies, for example, have revealed that hundreds of genes influence vulnerability to psychiatric disease and innate predisposition to risk-taking behaviors. This new edition has been thoroughly revised to focus on free will and its neurogenetic origins. In addition, the use of polygenic scores for behavioral prediction are discussed in-depth, reflecting the GWAS (Genome-Wide Association Study) revolution and combined use of genetic predictors in polygenic scores. Sections on epigenetics are also substantially expanded throughout, better defined, and tied to neuroplasticity and gene-environment interaction. Figures and illustrations have been added or improved throughout, and disease nosology and terminology has been updated. Updates on the previous edition which was the First Prize winner of the 2013 BMA Medical Book Award for Basic and Clinical Sciences Poses and resolves challenges to moral responsibility raised by modern genetics and neuroscience Analyzes the neurogenetic origins of human behavior and free will Features expanded sections on the neurogenetic basis of free will, polygenic risk scores, and epigenetic influence over behavior, as well as improved figures and updated terminology
Neurogenetics
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-01-09
Neurogenetics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-09 with Medical categories.
Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Genetic Neurobiology
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Author : Jeffrey C. Hall
language : en
Publisher: MIT Press (MA)
Release Date : 1982
Genetic Neurobiology written by Jeffrey C. Hall and has been published by MIT Press (MA) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Behavior genetics categories.
The neurogenetic approach to understanding the development, structure, and functioning of excitable cells and systems is a relatively new one. The results of this approach as described in this book, demonstrate that neurogenetics is already taking its place along side the traditional tools of physiology and biochemistry in the study of the nervous system.The book opens with a discussion of the basic cellular functions that underlie a variety of seemingly simple behaviors. It then proceeds to more complex phenomena, involving far more than one or a pair of excitable cells. Rather than developing the neurogenetic features of each experimental organism in isolation, topical features of the various organisms are discussed at appropriate points throughout.The subject is developed under three major headings: "Physiological and Neurochemical Genetics" sensory mechanisms, nerve impulses and ionic channels, and neurotransmission; "Behavioral Neurogenetics: "general motor mutants, visual behavior, circadian rhythms, learning and memory, reproductive behavior, and the neurochemistry of higher behavior, and "Developmental Neurogenetics" fate mapping of presumptive neural tissues, histogenesis and differentiation of excitable cells, inductive tissue interactions, neurospecificity, and physiological activity in development.Jeffrey C. Hall is affiliated with the Department of Biology, Brandeis University; Ralph J. Greenspan with the Department of Physiology, University of California Medical Center, San Francisco; and William A. Harris with the Department of Biology, University of California, San Diego. The book is another in a series that has evolved from a Work Session organized by MIT's Neurosciences Research Program.
Neurogenetics Of Psychiatric Disorders
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Author : Akira Sawa
language : en
Publisher: CRC Press
Release Date : 2007-05-11
Neurogenetics Of Psychiatric Disorders written by Akira Sawa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-11 with Medical categories.
Translating bench-based research into effective clinical practice, this source provides a clear understanding of the neurobiology and neurogenetics of psychiatric disorders, the genes responsible for specific psychiatric disorders, and the implications of genetic roots and underlying biology on the development of new diagnostic approaches and treat
Genetics And Genomics Of Neurobehavioral Disorders
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Author : Gene S. Fisch
language : en
Publisher: Humana
Release Date : 2010-11-09
Genetics And Genomics Of Neurobehavioral Disorders written by Gene S. Fisch and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-09 with Medical categories.
A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation. Comprehensive and up-to-date, Genetics and Genomics of Neurobehavioral Disorders integrates the molecular, genomic, neuropsychological, and neurobehavioral factors that produce learning disabilities and mental retardation into a coherent framework for the understanding and assessment of neurobehavioral disorders.
Foundations Of Behavior Genetics
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Author : Scott F. Stoltenberg
language : en
Publisher: Cambridge University Press
Release Date : 2022-07-07
Foundations Of Behavior Genetics written by Scott F. Stoltenberg and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-07 with Psychology categories.
Foundations of Behavior Genetics provides a forward-looking introduction to this fascinating field. Written by an experienced teacher and researcher, this text focuses on concepts, methods, and findings that inform our understanding of heredity–behavior relations. The book's neuroscience perspective asks students to think about potential neural mechanisms involved in pathways from genes to behavior. While the text is primarily focused on human behavior genetics, it also emphasizes the importance of non-human animal models in experimental studies, as well as their evolutionary connections to humans. Part I covers the history of behavior genetics and the basics of non-molecular genetics; Part II discusses molecular genetics and neurogenetics; Part III addresses various behavioral disorders; and Part IV explores health, social behavior, and ethical implications. The text includes detailed chapter summaries, several “Check-up” questions after major sections that test student understanding, and recommended readings. Instructors are provided with a test bank of multiple-choice items and hi-res JPEGs of the many illustrations created for the book.