Beta Lactam Antibiotics
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Beta Lactam Antibiotics
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Author : Susumu Mitsuhashi
language : en
Publisher: Springer
Release Date : 1981
Beta Lactam Antibiotics written by Susumu Mitsuhashi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.
The Chemistry Of Lactams
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Author : M.I. Page
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Chemistry Of Lactams written by M.I. Page and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Beta Lactam Antibiotics For Clinical Use
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Author : Stephen Queener
language : en
Publisher: CRC Press
Release Date : 1986-05-29
Beta Lactam Antibiotics For Clinical Use written by Stephen Queener and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-05-29 with Medical categories.
Presenting authoritative reviews of the sources of beta-lactam antibiotics, their mechanisms of action, manufacture, clinical utility, and pharmacology, this important volume gathers together the work of 33 distinguished experts to provide the most complete coverage of these drugs available in a single source. Beta-Lactam Antibiotics for Clinical Use organizes information from microbiology, fermentation science, organic chemistry, clinical medicine, pharmacokinetics, and pharmacodynamics in a unified, interdisciplinary approach ... focuses on the beta-lactams that are, or will shortly be, clinically significant ... identifies both present and projected markets for each antibiotic ... and examines general manufacturing methods for preparing each antibiotic, including the fermentation of intermediates. Containing over 2,300 bibliographic citations of the literature and numerous tables, drawings, and photographs, this book comprises a unique reference for microbiologists and cell biologists; pharmacologists; R & D personnel and research supervisors in the pharmaceutical industry; chemotherapists; toxicologists; industrial and medicinal chemists and biochemists; graduate students in microbiology and pharmacology; and continuing education and staff training programs in microbiology and pharmacology. Book jacket.
Chemistry And Biology Of Beta Lactam Antibiotics
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Author : Robert B. Morin
language : en
Publisher:
Release Date : 1982
Chemistry And Biology Of Beta Lactam Antibiotics written by Robert B. Morin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
The Biology Of B Lactam Antibiotics
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Author : Robert B. Morin
language : en
Publisher: Elsevier
Release Date : 2014-05-10
The Biology Of B Lactam Antibiotics written by Robert B. Morin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Medical categories.
The Biology of ß-Lactam Antibiotics
Synthesis Of Lactam Antibiotics
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Author : Alle Bruggink
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-27
Synthesis Of Lactam Antibiotics written by Alle Bruggink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-27 with Science categories.
Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Antibiotics
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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Antibiotics written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Antibiotic Drug Resistance
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Author : José-Luis Capelo-Martínez
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-24
Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-24 with Medical categories.
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Beta Lactam Antibiotics In Pregnancy
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Author : Anne Heikkilä
language : en
Publisher:
Release Date : 1992
Beta Lactam Antibiotics In Pregnancy written by Anne Heikkilä and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Antibiotics categories.
Penicillins And Cephalosporins
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Author : Robert B. Morin
language : en
Publisher: Academic Press
Release Date : 2014-05-10
Penicillins And Cephalosporins written by Robert B. Morin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Medical categories.
Chemistry and Biology of ?-Lactam Antibiotics, Volume 1: Penicillins and Cephalosporins provides information pertinent to the study of antibiotics containing the ?-lactam moiety. This book discusses the occurrence of a group of ?-lactam antibiotics structurally related to cephalosporin C. Organized into five chapters, this volume begins with an overview of the mechanism of action of ?-lactam antibiotics that caused many microbiologists to develop screening tools for the detection of the ?-lactam moiety. This text then discusses the discovery of the nocardicins, the thienamycins, and olivanic acids. Other chapters provide a summary of the essential penicillin sulfoxide chemistry that gave rise to many compounds. This book discusses as well the ability of chemists to predict the level of biological activity of a compound from knowledge of its structure through theoretical and physicochemical studies. The final chapter deals with quantitative structure–activity relationships. This book is a valuable resource for microbiologists, chemists, and scientists.