The Chemistry Of Lactams
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The Chemistry Of Lactams
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Author : M.I. Page
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Chemistry Of Lactams written by M.I. Page and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
The Organic Chemistry Of B Beta Lactams
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Author : Gunda I. Georg
language : en
Publisher:
Release Date : 1992
The Organic Chemistry Of B Beta Lactams written by Gunda I. Georg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Beta lactam antibiotics categories.
Synthesis Of Lactam Antibiotics
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Author : Alle Bruggink
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-27
Synthesis Of Lactam Antibiotics written by Alle Bruggink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-27 with Science categories.
Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
The Chemistry Of Beta Lactams
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Author : Michael I. Page
language : en
Publisher:
Release Date : 1992
The Chemistry Of Beta Lactams written by Michael I. Page and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Beta lactam antibiotics categories.
The Chemistry And Biology Of Beta Lactams
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Author : Daniel Zerong Wang
language : en
Publisher:
Release Date : 2023
The Chemistry And Biology Of Beta Lactams written by Daniel Zerong Wang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Beta lactamases categories.
"This new volume, The Chemistry and Biology of Beta-Lactams, provides the most updated information about beta-lactams relating to both the pharmaceutical industry and synthetic chemistry. It provides valuable information regarding antibiotic activities as well as chemical reactivities of beta-lactams, which are important because they are commonly applied as antibiotics in the treatment of bacterial infections. Presenting the most up-to-date literature information on beta-lactams, the volume provides comprehensive coverage of most of the known beta-lactam antibiotics with both structural and biological information, antibiotic mechanisms, self-defense mechanisms of bacteria, nearly all known synthetic methods for the preparation of beta-lactams, and possible reactions in which beta-lactams can participate. Key features: • Provides the most comprehensive collection of beta-lactam antibiotics (up to 269 molecules) with chemical structures, CAS number, IUPAC names and associated biological activities • Offers a comprehensive collection of beta-lactamase databases, where the features of each database have been described • Explains the self-defense mechanisms of bacteria for surviving, including the formation of biofilm and conversion into L-form, as well as secretion of beta-lactamase to deactivate the beta-lactam antibiotics • Provides a comprehensive survey on the synthetic methods to make beta-lactams • Gives all of the possible reactions involving beta-lactams as the starting materials • Surveys over 1000 research works and includes all available DOI information The important information provided here will be a valuable resource on the antibiotic activities as well as chemical reactivities of beta-lactams for researchers and scientists, faculty, and advanced students, as well as for industry professionals working in medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, proteins and peptides."--
Beta Lactams
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Author : Bimal K. Banik
language : en
Publisher: Springer
Release Date : 2017-05-11
Beta Lactams written by Bimal K. Banik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-11 with Science categories.
This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Lactams Unique Structures Of Distinction For Novel Molecules
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Author : Bimal K. Banik
language : en
Publisher: Springer
Release Date : 2012-09-28
Lactams Unique Structures Of Distinction For Novel Molecules written by Bimal K. Banik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-28 with Science categories.
I. Ojima • E. S. Zuniga • J. D. Seitz: Advances in the Use of Enantiopure β-Lactams for the Synthesis of Biologically Active Compounds of Medicinal Interests.- I. Fernández • Miguel A. Sierra: β -Lactams from Fischer Carbene Complexes: Scope, Limitations, and Reaction Mechanism.- Bablee Mandal • Basudeb Basu: Synthesis of β-Lactams Through Alkyne–Nitrone Cycloadditions.- T. T. Tidwell: Preparation of Bis-β-Lactams by Ketene–Imine Cycloadditions.- Edward Turos: The Chemistry and Biology of N-Thiolated β-Lactams.- Indrani Banik • Bimal K. Banik: Synthesis of β-Lactams and Their Chemical Manipulations Via Microwave-Induced Reactions.
Recent Advances In The Chemistry Of Lactam Antibiotics
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Author : Royal Society of Chemistry (Great Britain). Fine Chemicals and Medicinals Group
language : en
Publisher: CRC Press
Release Date : 1981
Recent Advances In The Chemistry Of Lactam Antibiotics written by Royal Society of Chemistry (Great Britain). Fine Chemicals and Medicinals Group and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.
Chemistry And Biology Of Beta Lactam Antibiotics
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Author : Robert B. Morin
language : en
Publisher:
Release Date : 1982
Chemistry And Biology Of Beta Lactam Antibiotics written by Robert B. Morin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
Beta Lactams Natural And Synthetic
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Author : Maghar S. Manhas
language : en
Publisher: John Wiley & Sons
Release Date : 1971
Beta Lactams Natural And Synthetic written by Maghar S. Manhas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.