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The Organic Chemistry Of B Beta Lactams


The Organic Chemistry Of B Beta Lactams
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The Organic Chemistry Of B Beta Lactams


The Organic Chemistry Of B Beta Lactams
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Author : Gunda I. Georg
language : en
Publisher:
Release Date : 1992

The Organic Chemistry Of B Beta Lactams written by Gunda I. Georg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Beta lactam antibiotics categories.




Synthesis Of Lactam Antibiotics


Synthesis Of Lactam Antibiotics
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Author : Alle Bruggink
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-27

Synthesis Of Lactam Antibiotics written by Alle Bruggink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-27 with Science categories.


Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.



Beta Lactams


Beta Lactams
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Author : Bimal K. Banik
language : en
Publisher: Springer
Release Date : 2017-05-11

Beta Lactams written by Bimal K. Banik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-11 with Science categories.


This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.



The Chemistry Of Lactams


The Chemistry Of Lactams
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Author : M.I. Page
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Chemistry Of Lactams written by M.I. Page and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)



Lactams Unique Structures Of Distinction For Novel Molecules


 Lactams Unique Structures Of Distinction For Novel Molecules
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Author : Bimal K. Banik
language : en
Publisher: Springer
Release Date : 2012-09-28

Lactams Unique Structures Of Distinction For Novel Molecules written by Bimal K. Banik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-28 with Science categories.


I. Ojima • E. S. Zuniga • J. D. Seitz: Advances in the Use of Enantiopure β-Lactams for the Synthesis of Biologically Active Compounds of Medicinal Interests.- I. Fernández • Miguel A. Sierra: β -Lactams from Fischer Carbene Complexes: Scope, Limitations, and Reaction Mechanism.- Bablee Mandal • Basudeb Basu: Synthesis of β-Lactams Through Alkyne–Nitrone Cycloadditions.- T. T. Tidwell: Preparation of Bis-β-Lactams by Ketene–Imine Cycloadditions.- Edward Turos: The Chemistry and Biology of N-Thiolated β-Lactams.- Indrani Banik • Bimal K. Banik: Synthesis of β-Lactams and Their Chemical Manipulations Via Microwave-Induced Reactions.



Heterocyclic Scaffolds I


Heterocyclic Scaffolds I
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Author : Bimal K. Banik
language : en
Publisher: Springer
Release Date : 2010-06-01

Heterocyclic Scaffolds I written by Bimal K. Banik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-01 with Science categories.


Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams



The Chemistry And Biology Of Beta Lactams


The Chemistry And Biology Of Beta Lactams
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Author : Zerong Wang
language : en
Publisher: CRC Press
Release Date : 2023-05-12

The Chemistry And Biology Of Beta Lactams written by Zerong Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-12 with Science categories.


Provides the most comprehensive collection of beta-lactam antibiotics (up to 269 molecules) with chemical structures, CAS number, IUPAC names and associated biological activities Offers a comprehensive collection of beta-lactamase databases, where the features of each database have been described Explains the self-defense mechanisms of bacteria for surviving, including the formation of biofilm and conversion into L-form, as well as secretion of beta-lactamase to deactivate the beta-lactam antibiotics Provides a comprehensive survey on the synthetic methods to make beta-lactams Gives all of the possible reactions involving beta-lactams as the starting materials Surveys over 1000 research works and includes all available DOI information



Houben Weyl Methods Of Organic Chemistry Vol E 16b 4th Edition Supplement


Houben Weyl Methods Of Organic Chemistry Vol E 16b 4th Edition Supplement
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Author :
language : de
Publisher: Georg Thieme Verlag
Release Date : 2014-05-14

Houben Weyl Methods Of Organic Chemistry Vol E 16b 4th Edition Supplement written by and has been published by Georg Thieme Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Science categories.


Houben-Weyl is the acclaimed reference series for preparative methods in organic chemistry, in which all methods are organized accor ding to the class of compound or functional group to be synthesized. The Houben-Weyl volumes contain 146 000 product-specific experi mental procedures, 580 000 structures, and 700 000 references. The preparative significance of the methods for all classes of compou nds is critically evaluated. The series includes data from as far back as the early 1800s to 2003. // The content of this e-book was originally published in 1991.



Enantioselective Synthesis Of Beta Amino Acids


Enantioselective Synthesis Of Beta Amino Acids
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Author : Eusebio Juaristi
language : en
Publisher: John Wiley & Sons
Release Date : 2005-05-06

Enantioselective Synthesis Of Beta Amino Acids written by Eusebio Juaristi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-06 with Science categories.


Covers all facets of the synthesis of ß-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ß-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ß-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ß-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ß-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ß-amino acid targets and salient ß-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ß-amino acids * Includes general and practical procedures for the preparation of ß-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ß-amino acids * Includes a report on the preparation of libraries of enantiopure ß-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ß-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.



Amino Acids Peptides And Proteins In Organic Chemistry Building Blocks Catalysis And Coupling Chemistry


Amino Acids Peptides And Proteins In Organic Chemistry Building Blocks Catalysis And Coupling Chemistry
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Author : Andrew B. Hughes
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-08

Amino Acids Peptides And Proteins In Organic Chemistry Building Blocks Catalysis And Coupling Chemistry written by Andrew B. Hughes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-08 with Science categories.


This is the third of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides This third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purification and automation. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.