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Bioactive Ceramides In Health And Disease


Bioactive Ceramides In Health And Disease
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Bioactive Ceramides In Health And Disease


Bioactive Ceramides In Health And Disease
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Author : Johnny Stiban
language : en
Publisher:
Release Date : 2019

Bioactive Ceramides In Health And Disease written by Johnny Stiban and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Biomedical engineering categories.


This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.



Bioactive Ceramides In Health And Disease


Bioactive Ceramides In Health And Disease
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Author : Johnny Stiban
language : en
Publisher: Springer Nature
Release Date : 2019-09-09

Bioactive Ceramides In Health And Disease written by Johnny Stiban and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-09 with Science categories.


This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.



Handbook Of Neurochemistry


Handbook Of Neurochemistry
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Author : Abel Lajtha
language : en
Publisher:
Release Date : 1982

Handbook Of Neurochemistry written by Abel Lajtha and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Neurochemistry categories.




Lipids In Health And Disease


Lipids In Health And Disease
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Author : Peter Quinn
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-27

Lipids In Health And Disease written by Peter Quinn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-27 with Medical categories.


Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.



The Role Of Bioactive Lipids In Cancer Inflammation And Related Diseases


The Role Of Bioactive Lipids In Cancer Inflammation And Related Diseases
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Author : Kenneth V. Honn
language : en
Publisher: Springer Nature
Release Date : 2019-09-27

The Role Of Bioactive Lipids In Cancer Inflammation And Related Diseases written by Kenneth V. Honn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-27 with Medical categories.


The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.



Sphingolipids As Signaling And Regulatory Molecules


Sphingolipids As Signaling And Regulatory Molecules
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Author : Charles Chalfant
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-12

Sphingolipids As Signaling And Regulatory Molecules written by Charles Chalfant and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-12 with Science categories.


This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases.



Sphingolipid Biology


Sphingolipid Biology
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Author : Y. Hirabayashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-31

Sphingolipid Biology written by Y. Hirabayashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-31 with Science categories.


Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids, as well as simpler sphingoid bases and derivatives, are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book reviews exciting new developments in sphingolipid biology/sphingolipidology that challenge our understanding of how multicellular organisms grow, develop, function, age, and die.



Sphingolipids Basic Science And Drug Development


Sphingolipids Basic Science And Drug Development
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Author : Erich Gulbins
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-11

Sphingolipids Basic Science And Drug Development written by Erich Gulbins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-11 with Medical categories.


Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids’ basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.



A Treatise On The Chemical Constitution Of The Brain


A Treatise On The Chemical Constitution Of The Brain
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Author : Johann Ludwig Wilhelm Thudichum
language : en
Publisher:
Release Date : 1962

A Treatise On The Chemical Constitution Of The Brain written by Johann Ludwig Wilhelm Thudichum and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1962 with Brain categories.




Inborn Disorders Of Sphingolipid Metabolism


Inborn Disorders Of Sphingolipid Metabolism
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Author : Stanley M. Aronson
language : en
Publisher: Elsevier
Release Date : 2017-01-31

Inborn Disorders Of Sphingolipid Metabolism written by Stanley M. Aronson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-31 with Health & Fitness categories.


Inborn Disorders of Sphingolipid Metabolism is a collection of papers presented at the Third International Symposium on the Cerebral Sphingolipidoses and Allied Diseases, held at the Isaac Albert Research Institute of the Jewish Chronic Disease Hospital and at the State University of New York, Downstate Medical Center, on October 25 and 26, 1965. This book is organized into three parts encompassing 35 chapters. Part I deals first with electron microscopic, histochemical, and morphological investigations of certain sphingolipid metabolism disorders. This part also examines several case reports on the features and symptoms of spongy degeneration of the central nervous system, familial leukodystrophy, adrenal insufficiency, and cutaneous melanosis. Part II surveys the metabolism, biosynthesis, and structure of gangliosides and sialic acids. This part also considers the nature of the lipophilic portions of the brain gangliosides. This part particularly looks into the features and clinical manifestation of Tay-Sachs disease. The third part covers the genetic and clinical aspects of the Tay-Sachs disease. This part also evaluates the genetics of the Hurler-Hunter syndrome, Batten-Spielmeyer-Vogt disease, and lipogranulomatosis syndrome. This book is of value to biochemists, histochemists, geneticists, and researchers in the allied fields of lipidosis.