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Biochemical And Biophysical Aspects Of Apoptin A Tumour Specific Apoptosis Inducing Protein


Biochemical And Biophysical Aspects Of Apoptin A Tumour Specific Apoptosis Inducing Protein
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Biochemical And Biophysical Aspects Of Apoptin A Tumour Specific Apoptosis Inducing Protein


Biochemical And Biophysical Aspects Of Apoptin A Tumour Specific Apoptosis Inducing Protein
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Author : Sirik Rutger Leliveld
language : en
Publisher:
Release Date : 2003

Biochemical And Biophysical Aspects Of Apoptin A Tumour Specific Apoptosis Inducing Protein written by Sirik Rutger Leliveld and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.




Biochemical And Biophysical Aspects Of Apoptin A Tumor Specific Apoptosis Inducing Protein


Biochemical And Biophysical Aspects Of Apoptin A Tumor Specific Apoptosis Inducing Protein
DOWNLOAD
Author : Sirik Rutger Leliveld
language : en
Publisher:
Release Date : 2003

Biochemical And Biophysical Aspects Of Apoptin A Tumor Specific Apoptosis Inducing Protein written by Sirik Rutger Leliveld and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.




Apoptin


Apoptin
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Author : Astrid Adriana Anna Maria Danen-van Oorschot
language : en
Publisher:
Release Date : 2001

Apoptin written by Astrid Adriana Anna Maria Danen-van Oorschot and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.




Tt Viruses


Tt Viruses
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Author : Ethel-Michele de Villiers
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-27

Tt Viruses written by Ethel-Michele de Villiers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-27 with Medical categories.


Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A –E hepatitis, subsequent studies failed to support this notion. Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept.



Nanopharmaceuticals Principles And Applications Vol 3


Nanopharmaceuticals Principles And Applications Vol 3
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Author : Vinod Kumar Yata
language : en
Publisher: Springer Nature
Release Date : 2020-08-19

Nanopharmaceuticals Principles And Applications Vol 3 written by Vinod Kumar Yata and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Technology & Engineering categories.


This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.



Intracellular Delivery


Intracellular Delivery
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Author : Aleš Prokop
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-26

Intracellular Delivery written by Aleš Prokop and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-26 with Science categories.


This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly upon existing conservative practices. This volume is a collection of authoritative reviews. In the introductory section we define the field (intracellular delivery). Then, the fundamental routes of nanodelivery devices, cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; at the academic and applied levels, are covered. The following section is dedicated to enhancing delivery via special targeting motifs followed by the introduction of different types of intracellular nanodelivery devices (e.g. a brief description of their chemistry) and ways of producing these different devices. Finally, we put special emphasis on particular disease states and on other biomedical applications, whilst diagnostic and sensing issues are also included. Intracellular delivery / therapy is a highly topical which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is great potential for targeted delivery with improved localized delivery and efficacy.



Advances In Breast Cancer Management 2nd Edition


Advances In Breast Cancer Management 2nd Edition
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Author : William J. Gradishar
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-08-31

Advances In Breast Cancer Management 2nd Edition written by William J. Gradishar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-31 with Medical categories.


The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh discusses the consequences of estrogen deprivation and the ways of ameliorating secondary symptoms and the potential long-term morbidity. Drs. Haigh and Guiliano review the sentinel lymph node biopsy technique including results from their extensive experience. Dr. Abram Recht places into perspective the potential benefit of post-mastectomy radiotherapy and reviews recent trials that address this issue. Dr. Dennis Slamon takes from us from the laboratory to the clinic in explaining the development of Herceptin as a paradigm for therapy targeted to specific molecular characteristics of breast cancer tumor cells. Drs. Nieto, Shpall, Crump and Pritchard offer different perspectives on the future of high-dose chemotherapy with stem cell transplantation as a treatment for breast cancer patients. Drs.



Necrotic Cell Death


Necrotic Cell Death
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Author : Han-Ming Shen
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-29

Necrotic Cell Death written by Han-Ming Shen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-29 with Science categories.


Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. ​In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.



Cpp Cell Penetrating Peptides


Cpp Cell Penetrating Peptides
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Author : Ülo Langel
language : en
Publisher: Springer Nature
Release Date : 2023-10-18

Cpp Cell Penetrating Peptides written by Ülo Langel and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-18 with Science categories.


In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo, is discussed. Therapeutic potential of CPPs and commercial developments are discussed. The present, second edition of this book is the updated and expanded version of the first edition, published in 2019. The development of the field of cell-penetrating peptides in these five years has been obvious and exciting. This second edition of the book has been partly reorganized and comprehensively expanded with the exciting research in 2019-2023. Around 2500 novel scientific articles have become available, most of them are reviewed in the second edition. Additional rapidly growing areas of high impact presented in this second edition are therapeutic developments (Chapter 16) and delivery of oligonucleotides and proteins/peptides (Chapters 5 and 6) including novel reports on genome editing with CPP assistance. Also, several additional examples are available now on clinical trials using CPPs (Chapter 15). The book is written for researchers and students in the field.



Cumulated Index Medicus


Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1996

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medicine categories.